1. Immunology/Inflammation
  2. CD47 Interleukin Related
  3. CC-90002

CC-90002 

目录号: HY-P99172 纯度: 97.97%
COA

CC-90002 是一种人源化抗 CD47 单克隆抗体 (mAb)。CC-90002 与 CD47 具有高亲和力,具有亚纳摩尔 Kd 值。CC-90002 可用于血液系统恶性肿瘤和实体瘤的研究。

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CC-90002 Chemical Structure

CC-90002 Chemical Structure

CAS No. : 2085844-54-6

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥7500
In-stock
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar Kd value. CC-90002 can be used for the research of hematologic malignancies and solid tumors[1][2].

种属

Humanized

体外研究
(In Vitro)

CC-90002 has a high affinity for binding to CD47 with a subnanomolar dissociation constant (Kd) value[1].
CC-90002 can block the CD47-SIRPa interaction with IC50 value in the subnanomolar range[1].
CC-90002 has inhibitory effect in concentration-dependent in the ALL and AML cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

CC-90002 shows significant dose-dependent antitumor activity and significant tumor regression in tumor xenografts models[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-P99172
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