2. Gene
  3. Cdc37 - cell division cycle 37 Gene

Cdc37 - cell division cycle 37 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p50; p50Cdc37

基因 ID: 12539 | 基因类型: protein coding

关于 Cdc37

功能概要

Enables HSP90 protein binding activity and kinase binding activity. Contributes to protein kinase regulator activity. Involved in positive regulation of Mitophagy in response to mitochondrial depolarization; posttranscriptional regulation of gene expression; and regulation of protein kinase activity. Located in cytosol. Part of HSP90-CDC37 chaperone complex. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Orthologous to human CDC37 (cell division cycle 37, HSP90 cochaperone). [provided by Alliance of Genome Resources, Apr 2022]

Cdc37 基因产物(2)

mRNA Protein Name
NM_001378796.1 NP_001365725.1 hsp90 co-chaperone Cdc37 isoform 1
NM_016742.5 NP_058022.1 hsp90 co-chaperone Cdc37 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp90 protein binding IDA
IDA: 通过直接分析推断
17189825 MGI
enables kinase binding IPI
IPI: 通过物理相互作用推断
21855797 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23428871 MGI
contributes to protein kinase regulator activity IDA
IDA: 通过直接分析推断
21855797 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of type 2 mitophagy IDA
IDA: 通过直接分析推断
21855797 MGI
involved in post-transcriptional regulation of gene expression IDA
IDA: 通过直接分析推断
21855797 MGI
involved in regulation of protein kinase activity IDA
IDA: 通过直接分析推断
21855797 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of HSP90-CDC37 chaperone complex IDA
IDA: 通过直接分析推断
21855797 MGI
located in cytosol IDA
IDA: 通过直接分析推断
17189825 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hsp90 co-chaperone Cdc37

cell division cycle 37 homolog

hsp90 chaperone protein kinase-targeting subunit

重组 Cdc37 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75362 CDC37 Protein, Mouse (sf9, His-GST) Q61081 (M1-A379) ≥95%
HY-P75363 CDC37 Protein, Mouse (sf9) Q61081 (N-G&P, M1-A379) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N1986 Cucurbitacin D 99.91% 否
HY-139301 DDO-5936 Inhibitor 99.20% 否
HY-144650 Hsp90-Cdc37-IN-3 98.09% 否
HY-N3417 Kongensin A ≥98.0% 否
HY-111414 Hsp90-Cdc37-IN-1 Inhibitor 99.66% 否
HY-119906 Conglobatin 95.48% 否
HY-130624 Hsp90-Cdc37-IN-2 / 否
HY-RS02297 CDC37 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS02298 CDC37L1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdc37 NCBI NCBI:11140
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