LTA - lymphotoxin alpha Gene

中文名称：淋巴毒素 α

种属: Rattus norvegicus

同用名: Tnfb

关于 LTA

功能概要

预测该基因编码的蛋白编码的蛋白可启动细胞因子活性和肿瘤坏死因子受体结合活性。参与多个过程，包括成纤维细胞增殖的负调节；神经胶质细胞增殖的正向调节；和对脂多糖的反应。位于细胞外空间。膀胱炎的生物标志物。该基因的人类直系同源物与多种疾病有关，包括动脉疾病（多种）；自身免疫性疾病（多种）；糖代谢疾病（多种）；利什曼病（多发）；和肺部疾病（多种）。与人类 LTA（淋巴毒素 α）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cytokine activity and tumor necrosis factor receptor binding activity. Involved in several processes, including negative regulation of fibroblast proliferation; positive regulation of glial cell proliferation; and response to lipopolysaccharide. Located in extracellular space. Biomarker of cystitis. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha). [provided by Alliance of Genome Resources, Apr 2022]