Dyrk2 - dual specificity tyrosine phosphorylation regulated kinase 2 Gene

中文名称：双特异性酪氨酸磷酸化调节激酶 2

种属: Rattus norvegicus

关于 Dyrk2

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动；金属离子结合活性；和蛋白激酶活性。预计参与多个过程，包括响应 p53 类介质对 DNA 损伤的内在凋亡信号通路；钙调磷酸酶-NFAT 信号级联的负调节；和蛋白质磷酸化。预计位于胞质溶胶和核质中。预测是核糖核蛋白复合物和泛素连接酶复合物的一部分。预计在细胞质中有活性；细胞骨架；和核。与人类 DYRK2（双重特异性酪氨酸磷酸化调节激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of calcineurin-NFAT signaling cascade; and protein phosphorylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of ribonucleoprotein complex and ubiquitin Ligase complex. Predicted to be active in cytoplasm; cytoskeleton; and nucleus. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2). [provided by Alliance of Genome Resources, Apr 2022]