1. Gene
  2. IFNA21 - interferon alpha 21 Gene

IFNA21 - interferon alpha 21 Gene

中文名称:干扰素α21

种属: Homo sapiens

同用名: LeIF F; leIF-F; IFN-alphaI

基因 ID: 3452 | 基因类型: protein coding

关于 IFNA21

Cytogenetic location: 9p21.3 Genomic coordinates (GRCh38): 9:21,165,637-21,166,660 (from NCBI)

This gene has 1 transcript (splice variant), 588 orthologues and 16 paralogues.

功能概要

该基因是位于 9 号染色体短臂上的 α 干扰素基因簇的成员。干扰素是响应病毒感染而产生的细胞因子,可介导免疫反应并干扰病毒复制。编码的蛋白质是一种 I 型干扰素,可能在对风疹病毒的抗病毒反应中发挥特定作用。[RefSeq 提供,2011 年 9 月]

This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral Infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the Antiviral response to rubella virus. [provided by RefSeq, Sep 2011]

IFNA21 基因产物(1)

mRNA Protein Name
NM_002175.2 NP_002166.2 interferon alpha-21 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IFNA21 蛋白结构

Interferon

Interferon: Interferon alpha/beta domain (26 - 187)

  • 0
  • 100
  • 189 a.a.
蛋白主名 其他名称

interferon alpha-21

IFN-alpha-21

关联疾病

疾病名称 别名
Rubella

German Measles

Three Day Measles

Rubella Nos

Multisystem Inflammatory Syndrome In Children

Mis-C

Multisystem Inflammatory Disorder In Children And Adolescents

Paediatric Inflammatory Multisystemic Syndrome

Mic

Melanoma, Cutaneous Malignant 1

Familial Melanoma

Melanoma, Cutaneous Malignant, Susceptibility To, 1

Melanoma, Malignant

CMM1

Melanoma, Cutaneous Malignant

Cmm

Familial Atypical Mole-Malignant Melanoma Syndrome

Fammm

Melanoma, Familial

Mlm

Dysplastic Nevus Syndrome, Hereditary

Dns

B-K Mole Syndrome

Melanoma, Cutaneous Malignant, 1

Malignant Melanoma, Cutaneous

Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

Dysplastic Nevus Syndrome

Cutaneous Melanoma

Familial Atypical Mole Melanoma Syndrome

Hereditary Melanoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma