1. Gene
  2. Asph - aspartate-beta-hydroxylase Gene

Asph - aspartate-beta-hydroxylase Gene

种属: Mus musculus

同用名: BAH; cI-37; 2310005F16Rik; 3110001L23Rik

基因 ID: 65973 | 基因类型: protein coding

关于 Asph

功能概要

Predicted to enable calcium ion binding activity and peptidyl-aspartic acid 3-dioxygenase activity. Involved in regulation of protein depolymerization and regulation of protein stability. Acts upstream of or within several processes, including face morphogenesis; limb morphogenesis; and peptidyl-aspartic acid hydroxylation. Located in cytoplasm. Is expressed in several structures, including eye; face; heart; limb; and trunk. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Orthologous to human ASPH (aspartate beta-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Asph 基因产物(11)

mRNA Protein Name
NM_001177849.1 NP_001171320.1 aspartyl/asparaginyl beta-hydroxylase isoform 3
NM_001177850.1 NP_001171321.1 aspartyl/asparaginyl beta-hydroxylase isoform 4
NM_001177851.1 NP_001171322.1 aspartyl/asparaginyl beta-hydroxylase isoform 5
NM_001177852.1 NP_001171323.1 aspartyl/asparaginyl beta-hydroxylase isoform 6
NM_001177853.1 NP_001171324.1 aspartyl/asparaginyl beta-hydroxylase isoform 7
NM_001177854.1 NP_001171325.1 aspartyl/asparaginyl beta-hydroxylase isoform 9
NM_001177855.1 NP_001171326.1 aspartyl/asparaginyl beta-hydroxylase isoform 8
NM_001177856.1 NP_001171327.1 aspartyl/asparaginyl beta-hydroxylase isoform 10
NM_001290367.1 NP_001277296.1 aspartyl/asparaginyl beta-hydroxylase isoform 11 precursor
NM_023066.3 NP_075553.2 aspartyl/asparaginyl beta-hydroxylase isoform 1
NM_133723.2 NP_598484.2 aspartyl/asparaginyl beta-hydroxylase isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22123818 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell population proliferation IGI
IGI: 通过遗传相互作用推断
11773073 MGI
acts upstream of or within face morphogenesis IMP
IMP: 通过突变表型推断
11773073 MGI
acts upstream of or within limb morphogenesis IMP
IMP: 通过突变表型推断
11773073 MGI
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
11773073 MGI
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
11773073 MGI
acts upstream of or within peptidyl-aspartic acid hydroxylation IDA
IDA: 通过直接分析推断
11773073 MGI
involved in regulation of protein depolymerization IDA
IDA: 通过直接分析推断
22123818 MGI
involved in regulation of protein stability IDA
IDA: 通过直接分析推断
22123818 MGI
acts upstream of or within roof of mouth development IMP
IMP: 通过突变表型推断
11773073 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22123818 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aspartyl/asparaginyl beta-hydroxylase

ASP beta-hydroxylase

aspartly beta-hydroxylase

aspartyl beta-hydroxylase Humbug

calsequestrin-binding protein

jumbug

junctate

junctin

peptide-aspartate beta-dioxygenase

重组 Asph 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77565 ASPH Protein, Mouse (His) Q8BSY0-1 (I324-I741) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asph NCBI NCBI:444