2. Gene
  3. Ido2 - indoleamine 2,3-dioxygenase 2 Gene

Ido2 - indoleamine 2,3-dioxygenase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：吲哚胺 2 ,3-双加氧酶 2

种属: Rattus norvegicus

同用名: IDO-2; Indol1

基因 ID: 681319 | 基因类型: protein coding

关于 Ido2

Primary_assembly 16: 67,459,190-67,496,324 forward strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 91 orthologues and is associated with 3 phenotypes. Restricted expression toward (RPKM 55.6).

功能概要

预测该基因编码的蛋白编码的蛋白可启动吲哚胺 2,3-双加氧酶活性和色氨酸 2,3-双加氧酶活性。预计参与从色氨酸和色氨酸分解代谢过程到犬尿氨酸的“从头”NAD 生物合成过程。预计在细胞质中有活性。与人类 IDO2（吲哚胺 2,3-双加氧酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable indoleamine 2,3-dioxygenase activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and tryptophan catabolic process to kynurenine. Predicted to be active in cytoplasm. Orthologous to human IDO2 (indoleamine 2,3-dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ido2 基因产物(8)

mRNA Protein Name
XM_039095218.1 XP_038951146.1 indoleamine 2,3-dioxygenase 2 isoform X4
XM_008771375.2 XP_008769597.2 indoleamine 2,3-dioxygenase 2 isoform X1
XM_039095217.1 XP_038951145.1 indoleamine 2,3-dioxygenase 2 isoform X3
XM_039095215.1 XP_038951143.1 indoleamine 2,3-dioxygenase 2 isoform X2
XM_039095215.1 XP_038951143.1 indoleamine 2,3-dioxygenase 2 isoform X2
XM_008771375.2 XP_008769597.2 indoleamine 2,3-dioxygenase 2 isoform X1
XM_039095218.1 XP_038951146.1 indoleamine 2,3-dioxygenase 2 isoform X4
XM_039095217.1 XP_038951145.1 indoleamine 2,3-dioxygenase 2 isoform X3

Ido2 蛋白结构

IDO

IDO: pfam01231 (14 - 398)

  • 0
  • 100
  • 200
  • 300
  • 405 a.a.
蛋白主名 其他名称

indoleamine 2,3-dioxygenase 2

indoleamine 2,3-dioxygenase-like protein 1

indoleamine-pyrrole 2,3 dioxygenase-like 1

indoleamine-pyrrole 2,3-dioxygenase-like protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100687 GNF-PF-3777 Inhibitor 98.03% 否
HY-151093 IDO2-IN-1 Inhibitor 98.86% 否
HY-145280 IDO1/2-IN-1 Inhibitor 98.06% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ido2 NCBI NCBI:169355
Mus musculus Ido2 NCBI NCBI:209176
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