FCRL5 - Fc receptor like 5 Gene

中文名称：Fc 受体样 5

种属: Homo sapiens

同用名: CD307; FCRH5; IRTA2; BXMAS1; CD307e; PRO820

基因 ID: 83416 | 基因类型: protein coding

关于 FCRL5

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:157,513,377-157,552,515 (from NCBI)

This gene has 8 transcripts (splice variants), 83 orthologues and 17 paralogues. Biased expression in lymph node (RPKM 14.3), spleen (RPKM 11.3) and 8 other tissues.

功能概要

该基因编码免疫球蛋白受体超家族和 Fc 受体样家族的成员。该基因和其他几个 Fc 受体样基因成员聚集在 1 号染色体的长臂上。编码的蛋白质是一种单程 I 型膜蛋白，包含 8 个免疫球蛋白样 C2 型结构域。该基因与 B 细胞发育和淋巴瘤形成有关。已经鉴定出编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2010 年 9 月]

This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

FCRL5 基因产物(2)

mRNA	Protein	Name
NM_001195388.2	NP_001182317.1	Fc receptor-like protein 5 isoform 2 precursor
NM_031281.3	NP_112571.2	Fc receptor-like protein 5 isoform 1 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables coreceptor activity	IDA IDA: 通过直接分析推断	30107486	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in B cell activation	IDA IDA: 通过直接分析推断	30107486	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cell surface	IDA IDA: 通过直接分析推断	16849395	GOA
is active in plasma membrane	IDA IDA: 通过直接分析推断	16849395	GOA
part of receptor complex	IDA IDA: 通过直接分析推断	23382219	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FCRL5 蛋白结构

Ig_2

Ig_3

Ig_2

0
200
400
600
800
977 a.a.

蛋白主名

其他名称

Fc receptor-like protein 5

fc receptor homolog 5

重组 FCRL5 蛋白

目录号	产品名	蛋白编号	纯度
HY-P77651	FcRH5/FcRL5 Protein, Human (HEK293, His-Avi)	Q96RD9-1 (Q16-G851)	≥95%
HY-P700302	FcRH5/FcRL5 Protein, Human (HEK293, His)	Q96RD9-1 (Q16-G851)	> 95% as determined by Tris-Bis PAGE.

关联疾病

疾病名称

别名

Hairy Cell Leukemia

Hcl-V	Hairy Cell Leukemia Variant
Hairy Cell Leukaemia Variant	Hcl
Leukemic Reticuloendotheliosis	Leukemic Reticuloendotheliosis Variant
Prolymphocytic Variant Of Hcl	Prolymphocytic Variant Of Hairy Cell Leukemia
Leukemia Hairy Cell	Leukemia, Hairy Cell
Leukaemic Reticuloendotheliosis	Lre - [Leukemic Reticuloendotheliosis]
Hairy-Cell Leukaemia, Nos	Hcl - [Hairy Cell Leukaemia]
Hairy-Cell Leukaemia Without Mention Of Remission

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Burkitt Lymphoma

Burkitt'S Lymphoma	BL
Burkitt Lymphoma, Somatic	Burkitt Lymphoma/Leukaemia
Burkitt'S Tumor	Burkitt'S Tumor Or Lymphoma
Malignant Lymphoma, Burkitt'S Type	Small Non-Cleaved Cell Lymphoma, Burkitt'S Type
Small Non-Cleaved Cell Lymphoma	Burkitt Tumor
Burkitts Lymphoma	Lymphoma, Small Noncleaved-Cell
Burkitt Tumour	Diffuse Small Noncleaved Malignant Burkitt Lymphoma
Malignant Burkitt Lymphoma	“Burkitt-Like” Lymphoma
Undifferentiated Burkitt Lymphoma	Small Noncleaved Cell Burkitt Lymphoma

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-160799	HA-9104	Inducer	98.06%	否
HY-RS04846	FCRL5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	FCRL5	RGD	RGD:1589379
Bos taurus	FCRL5	VGNC	VGNC:59181
Canis familiaris	FCRL5	VGNC	VGNC:49722
Felis catus	FCRL5	VGNC	VGNC:62216
Macaca mulatta	FCRL5	VGNC	VGNC:99950
Mus musculus	FCRL5	MGD	MGI:3053558
Macaca fascicularis	FCRL5	NCBI	NCBI:102119391
Others	FCRL5	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

FCRL5 - Fc receptor like 5 Gene

关于 FCRL5

功能概要

FCRL5 基因产物(2)

FCRL5 蛋白结构

重组 FCRL5 蛋白

关联疾病

直系同源

热门区域

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FCRL5 - Fc receptor like 5 Gene

关于 FCRL5

功能概要

FCRL5 基因产物(2)

FCRL5 蛋白结构

重组 FCRL5 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z