2. 重组蛋白
  3. CD Antigens Receptor Proteins
  4. NK Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Platelet CD Proteins Erythrocyte CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  5. ICAM-2/CD102 Immunoglobulin-like Cell Adhesion Molecules
  6. ICAM-2/CD102 蛋白, Mouse (HEK293, Fc)

ICAM-2/CD102 蛋白, Mouse (HEK293, Fc)

目录号: HY-P72620
产品使用指南

ICAM-2/CD102 蛋白是细胞相互作用的关键参与者，充当白细胞粘附蛋白 LFA-1 的配体。它抑制 LFA-1 依赖性细胞粘附并有助于淋巴细胞回收。ICAM-2/CD102 蛋白, Human (HEK293, His, solution) 是重组的 ICAM-2/CD102 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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100 μg   询价  

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描述

The ICAM-2/CD102 protein is a key player in cellular interactions, acting as a ligand for the leukocyte adhesion protein LFA-1. It inhibits LFA-1-dependent cell adhesion and contributes to lymphocyte recycling. ICAM-2/CD102 Protein, Human (HEK293, His, solution) is the recombinant mouse-derived ICAM-2/CD102 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

ICAM-2/CD102 蛋白作为细胞相互作用的重要参与者而出现，充当白细胞粘附蛋白 LFA-1（整合素 α-L/β-2）的配体。值得注意的是，ICAM-2 可能通过抑制 LFA-1 依赖性细胞粘附来促进淋巴细胞再循环。它的参与延伸到介导对各种免疫过程至关重要的粘附相互作用，包括抗原特异性免疫反应、NK 细胞介导的清除、淋巴细胞再循环以及对免疫反应和监视至关重要的其他细胞相互作用。该蛋白进一步与 RDX、EZR 和 MSN 相互作用，强调了其在免疫调节和监视基础的细胞机制中的复杂关联。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

P35330 (K23-Q222)
基因 ID
同用名
Intercellular adhesion molecule 2; ICAM-2; CD102
氨基酸序列

KAFEVYIWSEKQIVEATESWKINCSTNCAAPDMGGLETPTNKIMLEEHPQGKWKQFLVSNVSKDTVFFCHFTCSGKQHSESLNIRVYQPPAQVTLKLQPPRVFVGEDFTIECTVSPVQPLERLTLSLLRGRETLKNQTFGGAETVPQEATATFNSTALKKDGLNFSCQAELDLRPHGGYIIRSISEYQILEVYEPMQDNQ

分子量

70-90 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

ICAM-2/CD102 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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