1. 重组蛋白
  2. Enzymes & Regulators Biotinylated Proteins
  3. Protein Tyrosine Kinases
  4. NTRK3 蛋白, Human (Biotinylated, sf9, His, Avi)

NTRK3 蛋白, Human (Biotinylated, sf9, His, Avi)

目录号: HY-P702700
产品使用指南

TrkC 蛋白是一种受体酪氨酸激酶,对神经系统和潜在的心脏发育至关重要。NTF3/neurotropin-3 结合后,TrkC 发生自磷酸化,激活磷脂酰肌醇 3-激酶/AKT 和 MAPK 等途径。这些途径调节细胞存活和分化,强调 TrkC 在发育过程中重要细胞过程中的关键作用。NTRK3 蛋白, Human (Biotinylated, sf9, His, Avi) 是重组的 NTRK3 蛋白,由 Sf9 insect cells 表达,带有 Avi, His 标签。NTRK3 蛋白, Human (Biotinylated, sf9, His, Avi)

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描述

TrkC Protein, a receptor tyrosine kinase, crucially contributes to nervous system and potential heart development. Upon NTF3/neurotrophin-3 binding, TrkC undergoes autophosphorylation, activating pathways like phosphatidylinositol 3-kinase/AKT and MAPK. These pathways regulate cell survival and differentiation, emphasizing TrkC's pivotal role in essential cellular processes during development. NTRK3 Protein, Human (Biotinylated, sf9, His, Avi) is the recombinant human-derived NTRK3, expressed by Sf9 insect cells , with Avi, His labeled tag. ,

研究背景

TrkC 蛋白是一种受体酪氨酸激酶,在神经系统和潜在心脏发育中发挥着至关重要的作用。与其配体 NTF3/neurotropin-3 结合后,TrkC 发生自磷酸化,启动各种信号传导途径,例如磷脂酰肌醇 3-激酶/AKT 和 MAPK 途径。这些途径有助于调节细胞存活和分化,凸显了 TrkC 在协调发育过程中重要细胞过程中的关键作用。

种属

Human

表达系统

Sf9 insect cells

标签

Avi;His

蛋白编号

Q16288-1 (Y456-G825)

基因 ID

4916

同用名
TRKC; GP145-TrkC; gp145(trkC)
纯度

Greater than 80 % as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

NTRK3 Protein, Human (Biotinylated, sf9, His, Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
NTRK3 Protein, Human (Biotinylated, sf9, His, Avi)
目录号:
HY-P702700
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