TECTB 蛋白, Human (HEK293, His)

TECTB protein is a key noncollagenous component of the tegmental membrane of the inner ear that interacts with the stereocilia bundles of sensory hair cells. In response to sound stimulation, the movement of stereocilia relative to the tectorial membrane causes fluctuations in the hair cell membrane potential, converting sound into electrical signals. TECTB Protein, Human (HEK293, His) is the recombinant human-derived TECTB protein, expressed by HEK293 , with C-His labeled tag. The total length of TECTB Protein, Human (HEK293, His) is 287 a.a., with molecular weight of ~33.9 KDa.

TECTB 蛋白是盖膜内的主要非胶原成分之一，盖膜是一种位于内耳的细胞外基质，包裹耳蜗的神经上皮并与专门的感觉毛细胞的静纤毛束接触。响应声音刺激，导致这些毛细胞相对于盖膜运动，静纤毛偏转，导致毛细胞膜电位波动。该过程充当将声音转换为电信号的机制。TECTB 可以通过自缔合形成同聚丝，或者当与 α-tectorin 结合时形成异聚丝。此外，它与 CEACAM16 相互作用，进一步促进其在盖膜复杂结构和感觉功能中的功能作用。

Human

HEK293

C-His

Q96PL2/NP_478129.1 (K18-R304)

6975  [NCBI]

Approximately 33.9 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.