Tryptophan Hydroxylase 1/TPH-1 蛋白, Human (His)

The tryptophan hydroxylase 1 (TPH-1) protein is key to serotonin biosynthesis, catalyzing the rate-limiting step: the oxidation of L-tryptophan to 5-hydroxy-L-tryptophan. This enzyme activity is critical for the synthesis of serotonin, a neurotransmitter that affects mood, sleep, and appetite. Tryptophan Hydroxylase 1/TPH-1 Protein, Human (His) is the recombinant human-derived Tryptophan Hydroxylase 1/TPH-1 protein, expressed by E. coli , with N-His labeled tag. The total length of Tryptophan Hydroxylase 1/TPH-1 Protein, Human (His) is 443 a.a., with molecular weight of ~48 kDa.

色氨酸羟化酶 1 (TPH-1) 蛋白通过催化限速步骤（涉及 L-色氨酸氧化为 5-羟基-L-色氨酸），在血清素生物合成中发挥关键作用。这种酶活性对于血清素的合成至关重要，血清素是一种神经递质，在情绪调节、睡眠和食欲等各种生理过程中发挥重要作用。TPH-1 将 L-色氨酸转化为 5-羟基-L-色氨酸的能力是血清素途径中的关键调节步骤，凸显了其在神经递质产生和神经传递中的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-His

P17752 (I2-I444)

7166  [NCBI]

Approximately 48 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, 10% glycerol, pH 8.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.