5-Fluorouracil (Synonyms: 5-氟脲嘧啶; 5-FU)

目录号: HY-90006 纯度: 99.99%: FAQs
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摩尔计算器

5-Fluorouracil (5-FU) 是一种尿嘧啶的类似物 (nucleoside antimetabolite/analog)，是一种有效的抗肿瘤药。5-Fluorouracil 通过抑制胸苷酸合成酶影响嘧啶的合成，从而耗尽细胞内dTTP 池。5-Fluorouracil 诱导细胞凋亡 (apoptosis)，可用作化学敏化剂。5-Fluorouracil 还可抑制 HIV 病毒。5-Fluorouracil (5-FU) 可破坏外泌体特异性的 rRNA。

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5-Fluorouracil Chemical Structure

CAS No. : 51-21-8

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规格	价格	是否有货
10 mM * 1 mL in DMSO	￥500	In-stock
50 mg	￥140	In-stock
200 mg	￥350	In-stock
1 g	￥450	In-stock
5 g	￥840	In-stock
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Other Forms of 5-Fluorouracil:

MCE 顾客使用本产品发表的 203 篇科研文献

Proliferation Assay

IHC

RT-PCR

: 5-Fluorouracil purchased from MCE. Usage Cited in: Adv Sci (Weinh). 2022 Oct;9(30):e2200717. [Abstract]; A transient upregulation and subsequent downregulation of RSK2 phosphorylation at Thr577 by 5-Fluorouracil (5-FU), which is accompanied by the accumulation of γ‐H2AX phosphorylation in a time‐dependent manner.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Adv Sci (Weinh). 2022 Oct;9(30):e2200717. [Abstract]; In Hct116 cells, the inhibitory effects of 5-Fluorouracil (5-FU on cell growth at 2-10 μM are significantly enhanced by RSK2 or PAK4 inhibitors in short‐term and long‐term assays.

: 5-Fluorouracil purchased from MCE. Usage Cited in: J Immunother Cancer. 2022 Aug;10(8):e004006. [Abstract]; Hep3B and Huh7 cells are treated with 5-Fluorouracil for 24 h, then the cellular protein expression of p-IRF3 and pP65 is detected by immunoblotting.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Int J Biol Sci. 2022 Apr 11;18(7):2882-2897. [Abstract]; Representative immunoblots assessing apoptosis induced by 5-Fluorouracil (5-FU) in immortalized human ventricular myocytes (AC16).

: 5-Fluorouracil purchased from MCE. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; The combination of SR140333 or aprepitant and 5-Fluorouracil (5-FU; mg/kg) decreases the expression levels of ABCC1, ABCG2, p-ERK1/2, and c-Myc and increased those of p-PERK, ATF4, and CHOP compared with 5-FU treatment alone.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; Cell viability upon treatment with 5-Fluorouracil (5-FU; 60 μM), SR140333, or Aprepitant either as single agents or in combination at 24 h in HCT116 cells.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; ER stress pathways in HCT116/5-FU cells treated with 5-Fluorouracil (5-FU; 60 μM) with SR140333 or Aprepitant either as single agents or in combination at 24 h.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; Western blotting of drug-resistant proteins in HCT116/5-FU cells treated with 5-Fluorouracil (5-FU; 80 μM) at 48 h.

: 5-Fluorouracil purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2021 Apr 30;40(1):150. [Abstract]; Inhibition rate of proliferation in pcDNA3.1 or ZBTB28 transfected cells treated with gradient concentration of 5-FU for 72 hours.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026813118. [Abstract]; Overexpression of RMRP impairs 5-FU–induced p53 activation determined by RT-qPCR.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026813118. [Abstract]; Overexpression of RMRP impairs 5-FU-induced p53 activation determined by IB.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Cell Death Dis. 2021 Apr 1;12(4):338. [Abstract]; SW620, CACO2, and HCT15 cells are treated with different concentrations of UTD1 and 5-Fluorouracil (5-FU), and cell viability is measured by CCK-8.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Int J Biochem Cell Biol. 2018 Mar;96:9-19. [Abstract]; Hep3B cells are treated with 2 μmol Shikonin, 5-FU, BSNQ or OSNQ for different times (3, 6, 12 and 24 h), and stained with Annexin V and PI. The apoptotic cells are detected by fluorescence microscopy and quantified as percentages.

: 5-Fluorouracil purchased from MCE. Usage Cited in: J Cell Biochem. 2018 Nov 28. [Abstract]; MKN45 and MKN28 cells transfected with empty and DEC2 vectors are incubated in control medium or 5-Fu of 10 μM for 48 hours, then proliferation ratio of these cells is figured by EdU incorporation assay.

: 5-Fluorouracil purchased from MCE. Usage Cited in: J Cell Biochem. 2018 Nov 28. [Abstract]; The expressions of apoptotic-related proteins, cleaved-PARP, caspase-3-active are detected in control, STAT5A, STAT5A+5-Fu, DEC2+5-Fu, DEC2/STAT5A+5-Fu of MKN45 and MKN28 cell lines using Western blot analysis.

: 5-Fluorouracil purchased from MCE. Usage Cited in: J Cell Biochem. 2018 Nov 28. [Abstract]; The expressions of apoptotic-related proteins, cleaved-PARP, caspase-3-active and survivin are detected in MKN45, MKN45+5-Fu, MKN45-EV, MKN45-DEC2, MKN45-DEC2+5-Fu, MKN28, MKN28+5-Fu, MKN28-EV, MKN28-DEC2, MKN28-DEC2+5-Fu cells using Western blot analysis.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Med Sci Monit. 2018 Sep 21;24:6666-6672. [Abstract]; Expression of protein of OPA1, Mfn1, Mfn2, Drp1 and Fis1 in heart mitochondria of rats treated with different 5-FU concentrations. The control group is intraperitonealled injection with same amount of physiological saline.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Biochem Biophys Res Commun. 2018 Jun 27;501(3):636-642. [Abstract]; Immunoblot analysis of the expression levels of BCL-2 and BAX after treatment of HCT116 TP53^-/- cells with 20 μM 5-FU and 1.25 μM DHA alone or in combination for 48 h. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) served as a loading control.

: 5-Fluorouracil purchased from MCE. Usage Cited in: Tumour Biol. 2016 Jul;37(7):8811-24. [Abstract]; Assays for autophagy activity. Immunoblot analysis for LC3B. Compared with the Lenti-NC cells, the Lenti-CD44v6 cells display a higher intensity of autophagy flux but not steady-state levels when treated with 5-FU (*P<0.001).

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生物活性
实验参考方法
纯度 & 产品资料
参考文献

生物活性

5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer^[1]^[2]. 5-Fluorouracil also inhibits HIV^[3].

IC₅₀ & Target^[1]^[6]

HIV

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
143B	IC₅₀	13.01 μM Compound: FUra	Cytotoxicity against human 143B cells after 72 hrs by SRB assay Cytotoxicity against human 143B cells after 72 hrs by SRB assay	[PMID: 27073055]
143B	IC₅₀	16.31 μM Compound: FUra	Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay	[PMID: 27073055]
143B	IC₅₀	25.216 μM Compound: 5-FU	Antiproliferative activity against human 143B cells after 48 hrs by MTT assay Antiproliferative activity against human 143B cells after 48 hrs by MTT assay	[PMID: 29223717]
2008	IC₅₀	4.2 μM Compound: 1, 5-FU	Growth inhibition of human 2008 cells by crystal violet assay Growth inhibition of human 2008 cells by crystal violet assay	[PMID: 23075414]
4T1	IC₅₀	23 μM Compound: 5 Fluorouracil	Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
4T1	IC₅₀	28.12 μM Compound: 5-Fu	Anticancer activity against mouse 4T1 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against mouse 4T1 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
786-0	IC₅₀	> 10 μM Compound: 5-fluorouracil	Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
786-0	GI₅₀	0.72 μM Compound: 5-FU	Anticancer activity against human 786-0 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human 786-0 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
786-0	GI₅₀	0.72 μM Compound: 5-FU	Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
A2780	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human A2780 after 24 hrs by MTT assay Cytotoxicity against human A2780 after 24 hrs by MTT assay	[PMID: 19338315]
A2780	IC₅₀	0.65 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 18205316]
A2780	IC₅₀	14 μM Compound: 5-FU	Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
A2780	GI₅₀	3.5 μM Compound: 5FU	Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
A2780	GI₅₀	4.4 μM Compound: 5-FU	Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
A2780	IC₅₀	5 μM Compound: 5-Fu	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 16499317]
A2780	IC₅₀	5.1 μM Compound: 1, 5-FU	Growth inhibition of human A2780 cells by crystal violet assay Growth inhibition of human A2780 cells by crystal violet assay	[PMID: 23075414]
A2780	IC₅₀	5.4 μM Compound: 5-Fu	Cytotoxicity against human A2780 cells by MTT method Cytotoxicity against human A2780 cells by MTT method	[PMID: 23164710]
A2780	IC₅₀	7.21 μM Compound: 5-FU	Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
A-375	IC₅₀	21.09 μM Compound: 5-Fu	Anticancer activity against human A375 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against human A375 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
A-375	IC₅₀	3.52 μM Compound: 5-FU	Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
A-375	IC₅₀	46.55 μM Compound: 5-FU	Cytotoxicity against human A375 cells after 48 hrs by MTT assay Cytotoxicity against human A375 cells after 48 hrs by MTT assay	[PMID: 22483608]
A-375	IC₅₀	5.98 μM Compound: 5-Fu	Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
A-431	IC₅₀	0.018 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A431 cells after 48 hrs by MTT assay Antiproliferative activity against human A431 cells after 48 hrs by MTT assay	[PMID: 19423198]
A-431	IC₅₀	2.17 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human A431 cells after 48 hrs by MTT assay Cytotoxicity against human A431 cells after 48 hrs by MTT assay	[PMID: 20800480]
A-431	ED₅₀	44 μM Compound: 5-fluorouracil	Cytotoxicity against human A431 cells by MTT assay Cytotoxicity against human A431 cells by MTT assay	[PMID: 12027771]
A498	GI₅₀	0.35 μM Compound: 5-FU	Anticancer activity against human A498 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human A498 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
A498	GI₅₀	0.35 μM Compound: 5-FU	Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
A498	IC₅₀	8.83 μM Compound: 5-fluorouracil	Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
A549	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
A549	IC₅₀	> 100 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 31057737]
A549	IC₅₀	> 100 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) A549 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) A549 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
A549	IC₅₀	> 20 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
A549	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
A549	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
A549	IC₅₀	> 50 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
A549	IC₅₀	0.01 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 25259515]
A549	IC₅₀	0.18 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 18205316]
A549	GI₅₀	0.18 μM Compound: 5-FU	Anticancer activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
A549	GI₅₀	0.18 μM Compound: 5-FU	Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
A549	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human A549 after 24 hrs by MTT assay Cytotoxicity against human A549 after 24 hrs by MTT assay	[PMID: 19338315]
A549	ED₅₀	0.4 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 16309328]
A549	IC₅₀	0.42 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 22000925]
A549	IC₅₀	0.43 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 29254641]
A549	IC₅₀	0.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay	10.1039/C5MD00289C
A549	IC₅₀	0.69 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 32485532]
A549	IC₅₀	0.98 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay	[PMID: 24727462]
A549	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 24060486]
A549	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
A549	IC₅₀	1.16 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 27987485]
A549	IC₅₀	1.2 μM Compound: 5-F	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 28254697]
A549	IC₅₀	1.3 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 24835633]
A549	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26854375]
A549	IC₅₀	1.4 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 16499317]
A549	IC₅₀	1.54 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT method Cytotoxicity against human A549 cells by MTT method	[PMID: 23164710]
A549	IC₅₀	1.6 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 28431881]
A549	IC₅₀	1.65 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as reduction in cell growth by CCK8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell growth by CCK8 assay	[PMID: 33964443]
A549	IC₅₀	1.65 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay	[PMID: 24996138]
A549	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
A549	IC₅₀	1.9 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
A549	IC₅₀	10.32 μM Compound: 5-FU	Antiproliferative activity in human A549 cells after 72 hrs by MTT assay Antiproliferative activity in human A549 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
A549	IC₅₀	10.5 μg/mL Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
A549	IC₅₀	10.5 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28073676]
A549	IC₅₀	10.55 μM Compound: 5-FU	Cytotoxicity against human A549 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
A549	IC₅₀	10.65 μM Compound: 5-FU	Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
A549	GI₅₀	10.7 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay	[PMID: 32832031]
A549	IC₅₀	10.85 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 18644718]
A549	EC₅₀	100 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 20409617]
A549	IC₅₀	100.02 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
A549	IC₅₀	104.5 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human A549 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
A549	IC₅₀	108.7 μM Compound: 5-FU	Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
A549	IC₅₀	11.2 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
A549	IC₅₀	11.3 μM Compound: 5-fluorouracil	Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
A549	IC₅₀	11.4 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
A549	IC₅₀	11.42 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
A549	IC₅₀	12.8 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 22840493]
A549	IC₅₀	12.92 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28863355]
A549	IC₅₀	13.18 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
A549	IC₅₀	13.18 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 29635165]
A549	IC₅₀	13.95 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
A549	IC₅₀	14.15 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 26227777]
A549	IC₅₀	14.53 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay	[PMID: 32992255]
A549	IC₅₀	14.96 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
A549	IC₅₀	15.1 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28400238]
A549	IC₅₀	15.14 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
A549	IC₅₀	15.3 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
A549	IC₅₀	15.93 μM Compound: 2; 5-FU	Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
A549	IC₅₀	16.1 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28117202]
A549	IC₅₀	16.63 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 27913179]
A549	IC₅₀	16.96 μM Compound: 2; 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27322756]
A549	IC₅₀	17.02 μM Compound: 2; 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29202398]
A549	IC₅₀	17.3 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
A549	IC₅₀	19.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29486954]
A549	GI₅₀	19.76 μM Compound: 4; 5-FU	Antiproliferative activity against human A549 cells measured after 48 hrs by SRB assay Antiproliferative activity against human A549 cells measured after 48 hrs by SRB assay	[PMID: 32683166]
A549	IC₅₀	2 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 19700322]
A549	IC₅₀	2.05 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
A549	IC₅₀	2.05 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 30243153]
A549	GI₅₀	2.09 μM Compound: 5-FU	Growth inhibition of human A549 cells after 48 hrs by SRB assay Growth inhibition of human A549 cells after 48 hrs by SRB assay	[PMID: 28400235]
A549	IC₅₀	2.13 μM Compound: 5-Fluorouracil	Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
A549	IC₅₀	2.33 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
A549	IC₅₀	2.36 μM Compound: 5-Fluorouracil	Cytotoxicity activity against human A549 cells incubated for 48 hrs by SRB assay Cytotoxicity activity against human A549 cells incubated for 48 hrs by SRB assay	[PMID: 34119830]
A549	IC₅₀	2.4 μM Compound: 5-fluorouracil	Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
A549	GI₅₀	2.4 μM Compound: 5FU	Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
A549	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
A549	IC₅₀	2.53 μM Compound: 5-Fu	Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
A549	IC₅₀	2.65 μM Compound: 5-FU	Antitumor activity against human A549 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human A549 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
A549	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 29133046]
A549	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 27875779]
A549	IC₅₀	2.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay	[PMID: 25919052]
A549	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay	[PMID: 27311895]
A549	IC₅₀	2.9 mM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27847140]
A549	IC₅₀	20.13 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 24211021]
A549	IC₅₀	20.8 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells by SRB method Cytotoxicity against human A549 cells by SRB method	[PMID: 19422203]
A549	IC₅₀	21.58 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 27133593]
A549	IC₅₀	22.28 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26363869]
A549	IC₅₀	22.5 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
A549	IC₅₀	22.62 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
A549	IC₅₀	23.5 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 30108895]
A549	IC₅₀	23.57 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
A549	IC₅₀	24.66 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
A549	IC₅₀	24.87 μg/mL Compound: 5-F	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 24342667]
A549	IC₅₀	25.3 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
A549	IC₅₀	26 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	10.1039/C6MD00234J
A549	IC₅₀	27.08 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
A549	IC₅₀	28.64 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 30677614]
A549	IC₅₀	29.17 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
A549	IC₅₀	3.1 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells after 4 days by MTT assay Cytotoxicity against human A549 cells after 4 days by MTT assay	[PMID: 24359303]
A549	IC₅₀	3.1 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 18606546]
A549	IC₅₀	3.1 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT microassay Cytotoxicity against human A549 cells by MTT microassay	[PMID: 17320246]
A549	IC₅₀	3.2 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 22011319]
A549	IC₅₀	3.47 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26735909]
A549	IC₅₀	3.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTS assay Antiproliferative activity against human A549 cells after 72 hrs by MTS assay	[PMID: 27575478]
A549	IC₅₀	3.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTS assay Antiproliferative activity against human A549 cells after 72 hrs by MTS assay	[PMID: 26703795]
A549	IC₅₀	3.52 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTS assay Cytotoxicity against human A549 cells by MTS assay	[PMID: 29843103]
A549	IC₅₀	3.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 23665106]
A549	GI₅₀	3.6 μM Compound: fluorouracil	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 23964677]
A549	EC₅₀	3.61 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 12027739]
A549	IC₅₀	3.85 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
A549	IC₅₀	3.98 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27092413]
A549	IC₅₀	30.47 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
A549	IC₅₀	31.33 μM Compound: 5-FU	Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
A549	IC₅₀	31.52 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 22801644]
A549	IC₅₀	32.15 μM Compound: 5-Fu	Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 28011223]
A549	IC₅₀	32.4 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human A549 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
A549	IC₅₀	33.68 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 31945642]
A549	IC₅₀	34.27 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26883148]
A549	IC₅₀	34.27 μM Compound: 5FU	Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
A549	IC₅₀	34.33 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 24095745]
A549	IC₅₀	34.33 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23988357]
A549	IC₅₀	34.34 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 24953029]
A549	IC₅₀	34.47 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 28754470]
A549	IC₅₀	34.47 μM Compound: 5-FU	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 33109400]
A549	IC₅₀	35.05 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22483608]
A549	IC₅₀	35.41 μM Compound: Fluorouracil	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27128180]
A549	IC₅₀	35.41 μM Compound: Fluorouracil	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 25016234]
A549	IC₅₀	35.41 μM Compound: Fluorouracil	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22809558]
A549	IC₅₀	36.34 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
A549	IC₅₀	36.8 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay	[PMID: 29489361]
A549	IC₅₀	38.2 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 28371676]
A549	IC₅₀	38.23 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 2 days by MTT assay Cytotoxicity against human A549 cells after 2 days by MTT assay	[PMID: 25841196]
A549	IC₅₀	38.7 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 30737134]
A549	IC₅₀	39.86 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
A549	IC₅₀	39.86 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
A549	IC₅₀	4.1 μg/mL Compound: 5-Fu	Anticancer activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
A549	GI₅₀	4.2 μM Compound: 5-Fluorouracil	Growth inhibition of human A549 cells after 48 hrs by SRB assay Growth inhibition of human A549 cells after 48 hrs by SRB assay	[PMID: 28898082]
A549	IC₅₀	4.21 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay	[PMID: 23044370]
A549	IC₅₀	4.21 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 24956552]
A549	IC₅₀	4.3 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 30318440]
A549	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 31546197]
A549	IC₅₀	4.52 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
A549	GI₅₀	4.55 μM Compound: 5-fluorouracil	Growth inhibition of human A549 cells after 48 hrs by SRB assay Growth inhibition of human A549 cells after 48 hrs by SRB assay	[PMID: 24797798]
A549	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
A549	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
A549	IC₅₀	4.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 26222449]
A549	IC₅₀	40.38 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 2 days by MTT assay Cytotoxicity against human A549 cells after 2 days by MTT assay	[PMID: 24767839]
A549	IC₅₀	44.05 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Growth inhibition against human A549 cells after 48 hrs by MTT assay Growth inhibition against human A549 cells after 48 hrs by MTT assay	[PMID: 23999046]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23558238]
A549	IC₅₀	5.4 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
A549	IC₅₀	5.6 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 21515044]
A549	IC₅₀	5.62 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23920246]
A549	IC₅₀	5.64 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 22182926]
A549	IC₅₀	5.64 μM Compound: 5-Fu	Growth inhibition of human A549 cells after 48 hrs by MTT assay Growth inhibition of human A549 cells after 48 hrs by MTT assay	[PMID: 23353737]
A549	IC₅₀	5.64 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by after 48 hrs by MTT assay Cytotoxicity against human A549 cells by after 48 hrs by MTT assay	[PMID: 22579780]
A549	IC₅₀	5.91 μM Compound: 5-Fluoro uracil	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 19689125]
A549	IC₅₀	50.43 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
A549	IC₅₀	50.5 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by SRB method Cytotoxicity against human A549 cells after 72 hrs by SRB method	[PMID: 19324555]
A549	IC₅₀	50.5 μM Compound: 5-FU	In vitro inhibitory concentration required against human lung carcinoma A-549 cell line was determined after 72 hrs of drug exposure using SRB method In vitro inhibitory concentration required against human lung carcinoma A-549 cell line was determined after 72 hrs of drug exposure using SRB method	[PMID: 15380199]
A549	IC₅₀	51.64 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 25164762]
A549	IC₅₀	54.8 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22244588]
A549	IC₅₀	54.82 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
A549	IC₅₀	55.7 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29305189]
A549	IC₅₀	55.73 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 30007564]
A549	IC₅₀	56 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23356786]
A549	IC₅₀	6.6 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 34883453]
A549	IC₅₀	6.69 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
A549	IC₅₀	6.76 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 26595184]
A549	IC₅₀	6.8 μM Compound: 5-FU	Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 27537924]
A549	IC₅₀	6.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs	[PMID: 31945642]
A549	IC₅₀	66 μg/mL Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
A549	IC₅₀	69.07 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29958763]
A549	IC₅₀	7.1 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in viability after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as reduction in viability after 48 hrs by SRB assay	[PMID: 31103402]
A549	IC₅₀	7.1 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay	[PMID: 30248657]
A549	IC₅₀	7.244 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 26301558]
A549	IC₅₀	7.51 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 25870131]
A549	IC₅₀	7.62 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
A549	IC₅₀	71.09 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 30142612]
A549	IC₅₀	78 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by XTT method Cytotoxicity against human A549 cells after 48 hrs by XTT method	[PMID: 20151671]
A549	IC₅₀	8.12 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 35609396]
A549	IC₅₀	8.13 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay	[PMID: 27542307]
A549	IC₅₀	8.13 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay	[PMID: 26786698]
A549	IC₅₀	8.13 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay	[PMID: 25442303]
A549	IC₅₀	8.48 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29133051]
A549	IC₅₀	8.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
A549	IC₅₀	8.71 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 23685571]
A549	IC₅₀	8.83 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 22687745]
A549	IC₅₀	8.9 μM Compound: 5-Fu	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
A549	IC₅₀	8.92 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 24095094]
A549	IC₅₀	88.9 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23067549]
A549	IC₅₀	9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
A549	IC₅₀	9.19 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 18440233]
A549	IC₅₀	9.2 μM Compound: 5-FU	Cytotoxicity against A549 cells after 48 hrs by MTT assay Cytotoxicity against A549 cells after 48 hrs by MTT assay	[PMID: 17604394]
A549/TR	IC₅₀	112.23 μM Compound: 5-FU	Cytotoxicity against human A549/TAX cells after 72 hrs by MTT assay Cytotoxicity against human A549/TAX cells after 72 hrs by MTT assay	[PMID: 30677614]
A549/TR	IC₅₀	84.28 μM Compound: 5-FU	Cytotoxicity against human A549/T cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549/T cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
ACHN	GI₅₀	0.27 μM Compound: 5-FU	Anticancer activity against human ACHN cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human ACHN cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
ACHN	GI₅₀	0.29 μM Compound: 5-FU	Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
ACHN	IC₅₀	2.73 μM Compound: 5-fluorouracil	Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
ACHN	IC₅₀	9.874 μg/mL Compound: 5-FU	Cytotoxicity against human ACHN cells after 24 hrs by MTT assay Cytotoxicity against human ACHN cells after 24 hrs by MTT assay	[PMID: 23548704]
AGS	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human AGS cells after 72 hrs by SRB method Cytotoxicity against human AGS cells after 72 hrs by SRB method	[PMID: 19324555]
AGS	IC₅₀	11.04 μM Compound: 5-FU	Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
AGS	IC₅₀	23.24 μM Compound: 5-Fu	Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
AGS	GI₅₀	24.6 μM Compound: 5-FU	Antiproliferative activity against human AGS cells after 48 hrs by MTT assay Antiproliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 29040954]
AGS	GI₅₀	25 μM Compound: 5-Fu	Antiproliferative activity against human AGS cells after 48 hrs by MTT assay Antiproliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 28763647]
AGS	IC₅₀	29.6 μM Compound: 5-FU	Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 28947149]
AGS	IC₅₀	370 μM Compound: 5-FU	Cytotoxicity against AGS cells after 48 hrs by MTT assay Cytotoxicity against AGS cells after 48 hrs by MTT assay	[PMID: 17604394]
AGS	IC₅₀	58 μM Compound: 5-Fu	Cytotoxicity against human AGS cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human AGS cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 35191714]
AGS	EC₅₀	7.25 μM Compound: 5FU	Cytotoxicity against human AGS cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human AGS cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
ASPC1	IC₅₀	2.97 μM Compound: 5-FU	Cytotoxicity against human Aspc-1 cells by crystal violet staining Cytotoxicity against human Aspc-1 cells by crystal violet staining	[PMID: 20930123]
ASPC1	IC₅₀	98 μM Compound: 5-FU	Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
AZ-521 cell line	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
AZ-521 cell line	IC₅₀	> 20 μM Compound: 5-fluorouracil	Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
B16	IC₅₀	1.19 μM Compound: 5-Fu	Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
B16	IC₅₀	10.52 μM Compound: 5-FU	Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay	[PMID: 25529742]
B16	IC₅₀	12.62 μM Compound: 5-Fu	Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
B16	IC₅₀	17.85 μM Compound: 5-FU	Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay	[PMID: 25164762]
B16	IC₅₀	33 μM Compound: 5-fu	Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay	[PMID: 22304344]
B16	IC₅₀	4.2 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay	[PMID: 24332497]
B16	IC₅₀	7.64 μM Compound: 5-fluorouracil	Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25506718]
B16	IC₅₀	8.73 μM Compound: 5-FU	Cytotoxicity against mouse B16 cells by MTT assay Cytotoxicity against mouse B16 cells by MTT assay	[PMID: 18644718]
B16-BL6	IC₅₀	0.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 11575942]
B16-BL6	EC₅₀	1.23 μM Compound: 5-fluorouracil	Antiproliferative activity against mouse B16-BL6 cells after 72 hrs by MTT assay Antiproliferative activity against mouse B16-BL6 cells after 72 hrs by MTT assay	[PMID: 12027739]
B16-BL6	IC₅₀	5.78 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay	[PMID: 18440233]
B16-BL6	IC₅₀	7.39 μM Compound: 5-Fluoro uracil	Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay	[PMID: 19689125]
B16-F10	IC₅₀	0.87 μM Compound: 5-Fu	Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
B16-F10	IC₅₀	1.43 μM Compound: 5-Fu	Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
B16-F10	IC₅₀	21.41 μM Compound: 5-Fluorouracil	Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay	[PMID: 23312949]
B16-F10	IC₅₀	4 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse B16-F10 cells by MTT assay Cytotoxicity against mouse B16-F10 cells by MTT assay	[PMID: 29280630]
B16-F10	IC₅₀	6.29 μM Compound: 5-Fu	Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay	[PMID: 29254641]
BALB/3T3	IC₅₀	3.23 μM Compound: FUra	Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
Bcap37	IC₅₀	15.47 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 27133593]
Bcap37	IC₅₀	37.09 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
Bcap37	IC₅₀	47.09 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 26883148]
Bcap37	IC₅₀	47.1 μM Compound: 5FU	Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
Bcap37	IC₅₀	5.18 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
Bcap37	IC₅₀	5.18 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 25554922]
Bcap37	IC₅₀	5.33 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 22405648]
Bcap37	IC₅₀	5.58 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
Bcap37	IC₅₀	5.58 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 24119869]
Bel-7402	IC₅₀	> 500 μM Compound: 5-FU	Cytotoxicity against human Bel7402 cells assessed as growth inhibition by MTT assay Cytotoxicity against human Bel7402 cells assessed as growth inhibition by MTT assay	[PMID: 24684840]
Bel-7402	IC₅₀	> 700 μM Compound: 5-FU	Cytotoxicity against 5-fluorouracil-resistant human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against 5-fluorouracil-resistant human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26320625]
Bel-7402	IC₅₀	0.54 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human Bel 7402 cells by MTT assay Cytotoxicity against human Bel 7402 cells by MTT assay	[PMID: 18205316]
Bel-7402	IC₅₀	10.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 26227777]
Bel-7402	IC₅₀	11.12 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 24819956]
Bel-7402	IC₅₀	11.78 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 25529742]
Bel-7402	IC₅₀	14.41 μM Compound: 5-FU	Cytotoxicity against human BEL-7402 cells by MTT assay Cytotoxicity against human BEL-7402 cells by MTT assay	[PMID: 18644718]
Bel-7402	IC₅₀	14.91 μM Compound: 5-FU	Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
Bel-7402	IC₅₀	15.6 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay	[PMID: 30851694]
Bel-7402	IC₅₀	17.59 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
Bel-7402	IC₅₀	18.49 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 29524728]
Bel-7402	IC₅₀	18.49 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 29407983]
Bel-7402	IC₅₀	18.65 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
Bel-7402	IC₅₀	18.65 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 30243153]
Bel-7402	IC₅₀	18.97 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 29635169]
Bel-7402	IC₅₀	19.84 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
Bel-7402	IC₅₀	19.91 μM Compound: 5-Fluorouracil	Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
Bel-7402	IC₅₀	2.23 μM Compound: 5-FU	Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
Bel-7402	IC₅₀	2.25 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 28165738]
Bel-7402	IC₅₀	20.93 μM Compound: 5-Fu	Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay	[PMID: 29174813]
Bel-7402	IC₅₀	21.3 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
Bel-7402	IC₅₀	214.33 μM Compound: 5-FU	Antiproliferative activity in 5-FU resistant human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity in 5-FU resistant human Bel7402 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
Bel-7402	IC₅₀	23.21 μM Compound: fluorouracil	Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay	[PMID: 17291040]
Bel-7402	IC₅₀	4.2 μM Compound: 5-Fu	Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay	[PMID: 16499317]
Bel-7402	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bel7402 after 72 hrs by MTT assay Cytotoxicity against human Bel7402 after 72 hrs by MTT assay	[PMID: 19233650]
Bel-7402	IC₅₀	4.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay	[PMID: 19560842]
Bel-7402	IC₅₀	5.5 μM Compound: 5-fluorouracil	Cytotoxicity against human Bel7402 cells after 4 days by MTT assay Cytotoxicity against human Bel7402 cells after 4 days by MTT assay	[PMID: 24359303]
Bel-7402	IC₅₀	5.94 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay	[PMID: 28301815]
Bel-7402	IC₅₀	53.33 μM Compound: 5-FU	Cytotoxicity against human Bel7402 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Bel7402 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
Bel-7402	IC₅₀	7.36 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay	[PMID: 31553932]
Bel-7402	IC₅₀	7.57 μM Compound: 5-FU	Antiproliferative activity in human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity in human Bel7402 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
Bel-7402	IC₅₀	8.3 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells by MTT assay Antiproliferative activity against human Bel7402 cells by MTT assay	[PMID: 24095094]
Bel7402/5-FU	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay	[PMID: 28301815]
Bel7402/5-FU	IC₅₀	> 400 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay	[PMID: 31553932]
Bel7402/5-FU	IC₅₀	> 80 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay	[PMID: 29524728]
Bel7402/5-FU	IC₅₀	> 80 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay	[PMID: 29407983]
Bel7402/5-FU	IC₅₀	38.24 μM Compound: 5-FU	Cytotoxicity against human Bel7402/5-FU cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Bel7402/5-FU cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
Bel7402/5-FU	IC₅₀	61.7 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay	[PMID: 30851694]
Bel7402/5-FU	IC₅₀	935.78 μM Compound: 5-FU	Cytotoxicity against human Bel7402/5-FU cells after 72 hrs by MTT assay Cytotoxicity against human Bel7402/5-FU cells after 72 hrs by MTT assay	[PMID: 30677614]
BEL-7404 tumor cell line	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human Bel7404 after 24 hrs by MTT assay Cytotoxicity against human Bel7404 after 24 hrs by MTT assay	[PMID: 19338315]
BEL-7404 tumor cell line	IC₅₀	26.8 μM Compound: 5-FU	Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay	[PMID: 24565905]
BEL-7404 tumor cell line	IC₅₀	30.23 μM Compound: 5-FU	Cytotoxic activity against human Bel7404 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human Bel7404 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
BEL-7404 tumor cell line	IC₅₀	40.21 μM Compound: 5-FU	Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay	[PMID: 30092368]
BGC-823	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human BGC823 after 24 hrs by MTT assay Cytotoxicity against human BGC823 after 24 hrs by MTT assay	[PMID: 19338315]
BGC-823	IC₅₀	0.7 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human BGC 823 cells by MTT assay Cytotoxicity against human BGC 823 cells by MTT assay	[PMID: 18205316]
BGC-823	IC₅₀	1.52 μM Compound: 5-Fluorouracil	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method	[PMID: 23018096]
BGC-823	IC₅₀	100.02 μM Compound: 5-FU	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 21962523]
BGC-823	IC₅₀	14.02 μM Compound: 5-Fu	Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
BGC-823	IC₅₀	15.4 μM Compound: 5-fluorouracil	Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
BGC-823	IC₅₀	15.65 μM Compound: 5-Fu	Cytotoxicity against human BGC823 cells by MTT assay Cytotoxicity against human BGC823 cells by MTT assay	[PMID: 22801644]
BGC-823	EC₅₀	17.37 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 21889345]
BGC-823	IC₅₀	17.37 μM Compound: 5-Fluorouracil	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 28363444]
BGC-823	IC₅₀	24.8 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 30527868]
BGC-823	IC₅₀	3.84 μM Compound: 5-Fu	Cytotoxicity against human BGC823 cells by MTT method Cytotoxicity against human BGC823 cells by MTT method	[PMID: 23164710]
BGC-823	IC₅₀	31.16 μM Compound: fluorouracil	Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 17291040]
BGC-823	IC₅₀	34.8 μM Compound: 5-FU	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 30108895]
BGC-823	IC₅₀	34.8 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 28073676]
BGC-823	IC₅₀	35.6 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
BGC-823	IC₅₀	37 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
BGC-823	IC₅₀	4.5 μM Compound: 5-FU	Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay	[PMID: 22727445]
BGC-823	IC₅₀	5.4 μM Compound: 5-Fu	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 16499317]
BGC-823	IC₅₀	5.89 μM Compound: 5-Fu	Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
BGC-823	IC₅₀	7.48 μM Compound: 5-FU	Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 24286761]
BGC-823	IC₅₀	8.2 μg/mL Compound: 5-FU	Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay	[PMID: 22647218]
BGC-823	IC₅₀	8.82 μM Compound: 5-FU	Cytotoxicity against human BGC823 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human BGC823 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
BT-20	IC₅₀	47.3 μM Compound: 5FU	Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
BT-474	IC₅₀	72.9 μM Compound: 5-Fu	Cytotoxicity against human BT474 cells after 3 days by MTT assay Cytotoxicity against human BT474 cells after 3 days by MTT assay	[PMID: 22000925]
BT-549	GI₅₀	10.6 μM Compound: 5-FU	Anticancer activity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
BT-549	GI₅₀	10.6 μM Compound: 5-FU	Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
BT-549	IC₅₀	19.82 μM Compound: 5-FU	Cytotoxicity against human BT549 cells after 48 hrs by MTT assay Cytotoxicity against human BT549 cells after 48 hrs by MTT assay	[PMID: 27397498]
BT-549	IC₅₀	19.82 μM Compound: 5-FU	Anticancer activity against human BT549 cells after 48 hrs by MTT assay Anticancer activity against human BT549 cells after 48 hrs by MTT assay	[PMID: 26413726]
BT-549	IC₅₀	98.24 μM Compound: Fluorouracil	Cytotoxicity against human BT549 cells after 48 hrs by MTT assay Cytotoxicity against human BT549 cells after 48 hrs by MTT assay	[PMID: 28789892]
BXPC-3	EC₅₀	0.14 μM Compound: 1; 5-FU	Antiproliferative activity against human BxPC-3 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay Antiproliferative activity against human BxPC-3 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay	[PMID: 34979089]
BXPC-3	GI₅₀	2.9 nM Compound: 5FU	Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay	[PMID: 23094992]
BXPC-3	GI₅₀	8.2 μM Compound: 5-Fu	Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay	[PMID: 22512908]
C13	IC₅₀	12.1 μM Compound: 5FU	Cytotoxicity against human C13 cells after 72 hrs Cytotoxicity against human C13 cells after 72 hrs	[PMID: 30035541]
C13	IC₅₀	8.5 μM Compound: 1, 5-FU	Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay	[PMID: 23075414]
C170	IC₅₀	0.3 μg/mL Compound: 5-FU	Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro	[PMID: 8496926]
C170	IC₅₀	2 μM Compound: 5-FU	Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro	[PMID: 8496926]
C-33-A	IC₅₀	4.61 μM Compound: 5-FU	Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
Ca9-22	CC₅₀	13 μM Compound: 5-FU	Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32795767]
Ca9-22	CC₅₀	262 μM Compound: 5-FU	Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31532650]
Caco-2	IC₅₀	1.5 μM Compound: 5-Fu	Growth inhibition of human Caco-2 cells after 10 days Growth inhibition of human Caco-2 cells after 10 days	[PMID: 18037195]
Caco-2	IC₅₀	1.5 μM Compound: 5FU	Growth inhibition of human Caco-2 cells after 10 days Growth inhibition of human Caco-2 cells after 10 days	[PMID: 17555969]
Caco-2	IC₅₀	1.5 μM Compound: 5-FU	Growth inhibition of human Caco-2 cells after 10 days Growth inhibition of human Caco-2 cells after 10 days	[PMID: 17337193]
Caco-2	GI₅₀	2.2 μM Compound: 5-FU	Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control	[PMID: 26539626]
Caco-2	IC₅₀	21 μM Compound: 5-Fluorouracil	Cytotoxicity against Homo sapiens (human) Caco2 cells after 48 hr by SRB assay Cytotoxicity against Homo sapiens (human) Caco2 cells after 48 hr by SRB assay	10.1007/s00044-012-0424-0
Caco-2	IC₅₀	21 μM Compound: 5-Fluorouracil	Cytotoxicity against human Caco2 cells assessed as inhibition of cell proliferation after 48 hrs by sulforhodamine-B assay Cytotoxicity against human Caco2 cells assessed as inhibition of cell proliferation after 48 hrs by sulforhodamine-B assay	10.1039/C3MD00055A
Caco-2	GI₅₀	3.3 μM Compound: 5-FU	Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay	[PMID: 27504537]
Caco-2	IC₅₀	31 μM Compound: 5-FU	Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 28463785]
Caco-2	IC₅₀	38.77 μM Compound: 5-FU	Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay	[PMID: 29635169]
Caco-2	CC₅₀	384.4 μM Compound: 5-Fu	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 18037195]
Caco-2	CC₅₀	384.4 μM Compound: 5FU	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 17555969]
Caco-2	CC₅₀	384.4 μM Compound: 5FU	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 17548129]
Caco-2	CC₅₀	384.4 μM Compound: 5-FU	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 17337193]
Caco-2	IC₅₀	60 μM Compound: 5-Fluorouracil	Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay	[PMID: 28793973]
Caco-2	IC₅₀	7.77 μM Compound: 5-FU	Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34170142]
Caco-2	IC₅₀	7.8 μM Compound: 5-fluorouracil	Cytotoxicity against human Caco2 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human Caco2 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
CAKI-1	GI₅₀	0.07 μM Compound: 5-FU	Anticancer activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
CAKI-1	GI₅₀	0.07 μM Compound: 5-FU	Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
CAL-27	IC₅₀	0.5 μg/mL Compound: 5-FU	Antiproliferative activity against human CAL-27 cells assessed as cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human CAL-27 cells assessed as cell viability measured after 72 hrs by MTT assay	[PMID: 34463097]
CAMA-1	IC₅₀	1.28 μM Compound: 5FU	Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human non-small cell lung cancer cells after 48 hrs by SRB assay Growth inhibition of human non-small cell lung cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by SRB assay Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-fu	Antitumor activity against human non small cell lung cancer cells after 48 hrs by SRB assay Antitumor activity against human non small cell lung cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells at 10 uM after 48 hrs Cytotoxicity against human non-small cell lung cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-fu	Antiproliferative activity against human non-small cell lung cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human non-small cell lung cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	IC₅₀	2.3 μM Compound: 5-Florouracil	Anticancer activity against Homo sapiens (human) NCI lung cancer cell assessed as inhibition of cell proliferation after 24 hr by MTT assay Anticancer activity against Homo sapiens (human) NCI lung cancer cell assessed as inhibition of cell proliferation after 24 hr by MTT assay	10.1007/s00044-012-0260-2
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-fu	Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-fu	Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Growth inhibition of human prostate cancer cells after 48 hrs Growth inhibition of human prostate cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	IC₅₀	3.6 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate TSU cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate TSU cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Growth inhibition of human renal cancer cells after 48 hrs by SRB assay Growth inhibition of human renal cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-fu	Antitumor activity against human renal cancer cells after 48 hrs by SRB assay Antitumor activity against human renal cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-fu	Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Growth inhibition of human renal cancer cells after 48 hrs Growth inhibition of human renal cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	IC₅₀	6.4 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate PPC-1 cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate PPC-1 cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Growth inhibition of human ovarian cancer cells after 48 hrs by coulter counter method Growth inhibition of human ovarian cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counting Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Growth inhibition of human ovarian cancer cells after 48 hrs by SRB assay Growth inhibition of human ovarian cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by SRB assay Cytotoxicity against human ovarian cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-fu	Antitumor activity against human ovarian cancer cells after 48 hrs by SRB assay Antitumor activity against human ovarian cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells at 10 uM after 48 hrs Cytotoxicity against human ovarian cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human ovarian cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-fu	Antiproliferative activity against human ovarian cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human ovarian cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Growth inhibition of human ovarian cancer cells after 48 hrs Growth inhibition of human ovarian cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	72.07 μM Compound: 5-FU	Growth inhibition of human CNS cancer cells after 48 hrs Growth inhibition of human CNS cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Growth inhibition of human CNS cancer cells after 48 hrs by coulter counter method Growth inhibition of human CNS cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counting Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Growth inhibition of human CNS cancer cells after 48 hrs by SRB assay Growth inhibition of human CNS cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by SRB assay Cytotoxicity against human CNS cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-fu	Antitumor activity against human CNS cancer cells after 48 hrs by SRB assay Antitumor activity against human CNS cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells at 10 uM after 48 hrs Cytotoxicity against human CNS cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human CNS cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-fu	Antiproliferative activity against human CNS cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human CNS cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human breast cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Growth inhibition of human breast cancer cells after 48 hrs by coulter counter method Growth inhibition of human breast cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by coulter counting Cytotoxicity against human breast cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Growth inhibition of human breast cancer cells after 48 hrs by SRB assay Growth inhibition of human breast cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by SRB assay Cytotoxicity against human breast cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-fu	Antitumor activity against human breast cancer cells after 48 hrs by SRB assay Antitumor activity against human breast cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells at 10 uM after 48 hrs Cytotoxicity against human breast cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human breast cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-fu	Antiproliferative activity against human breast cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human breast cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Growth inhibition of human breast cancer cells after 48 hrs Growth inhibition of human breast cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	8.37 μM Compound: 5-FU	Growth inhibition of human Colon cancer cells after 48 hrs Growth inhibition of human Colon cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Growth inhibition of human colon cancer cells after 48 hrs by SRB assay Growth inhibition of human colon cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-fu	Antitumor activity against human colon cancer cells after 48 hrs by SRB assay Antitumor activity against human colon cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-fu	Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
CAPAN-1	IC₅₀	0.47 μM Compound: 5-fluorouracil	Antiproliferative activity against human Capan-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay Antiproliferative activity against human Capan-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay	[PMID: 32007666]
Capan-2	IC₅₀	54.247 μM Compound: 5-Fluorouracil	Cytotoxicity against human Capan2 cells incubated for 24 hrs by MTT assay Cytotoxicity against human Capan2 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
CCD-18Co	IC₅₀	> 200 μM Compound: 5-FU	Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32203786]
CCD-18Co	IC₅₀	9.26 μM Compound: 5-Fu	Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay	[PMID: 24704691]
CCD-841CoN	IC₅₀	> 25 μM Compound: 5-FU	Antiproliferative activity against human CRL1790 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay Antiproliferative activity against human CRL1790 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay	[PMID: 23305919]
CCD-841CoN	GI₅₀	10.3 μM Compound: 5-FU	Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay	[PMID: 28716495]
CCD-841CoN	EC₅₀	218 μM Compound: 5FU	Cytotoxicity against human CCD-841CoN cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human CCD-841CoN cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
CCD-841CoN	IC₅₀	35.7 μM Compound: 5-FU	Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay	[PMID: 30037494]
CCRF-CEM	IC₅₀	12 μM Compound: 1, 5-FU	Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting	[PMID: 21892829]
CCRF-CEM	IC₅₀	125 μM Compound: 5-FU	Antiproliferative activity against human CEM cells after 72 hrs by MTT assay Antiproliferative activity against human CEM cells after 72 hrs by MTT assay	[PMID: 19743863]
CCRF-CEM	IC₅₀	14 μM Compound: 5-FU	Cytostatic activity against human CEM cells after 3 days by coulter counting analysis Cytostatic activity against human CEM cells after 3 days by coulter counting analysis	[PMID: 21330014]
CCRF-CEM	IC₅₀	14 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 3 days by coulter counter analysis Cytotoxicity against human CEM cells after 3 days by coulter counter analysis	[PMID: 21232828]
CCRF-CEM	IC₅₀	15 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Cytostatic activity against human CEM cells after 3 days by coulter counter analysis Cytostatic activity against human CEM cells after 3 days by coulter counter analysis	[PMID: 22405290]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method	[PMID: 27750154]
CCRF-CEM	IC₅₀	18 μM Compound: 5-FU	Cytostatic activity against human CEM cells after 72 hrs by Coulter counting Cytostatic activity against human CEM cells after 72 hrs by Coulter counting	[PMID: 25435471]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method	[PMID: 24906510]
CCRF-CEM	IC₅₀	18 μM Compound: 5FU	Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay	[PMID: 24631358]
CCRF-CEM	IC₅₀	18 μM Compound: 1, 5-FU	Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting	[PMID: 21892829]
CCRF-CEM	IC₅₀	30 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 72 hrs by MTT assay Cytotoxicity against human CEM cells after 72 hrs by MTT assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	32 μM Compound: 5-Fluorouracil	Cytotoxicity against human CEM cells after 72 hrs by MTT assay Cytotoxicity against human CEM cells after 72 hrs by MTT assay	[PMID: 23535322]
CCRF-CEM	IC₅₀	4 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human leukemia cell line CCRF CEM after 72 hr of incubation The compound was evaluated for antitumoral activity against human leukemia cell line CCRF CEM after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
CCRF-CEM	IC₅₀	40 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 48 hrs by MTT assay Cytotoxicity against human CEM cells after 48 hrs by MTT assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	8 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	9.23 μM Compound: 5-FU	Antiproliferative activity against human CEM cells after 3 days by MTT assay Antiproliferative activity against human CEM cells after 3 days by MTT assay	[PMID: 18424155]
CCRF-CEM	GI₅₀	9.79 μM Compound: 5-FU	Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
CCRF-CEM	GI₅₀	9.97 μM Compound: 5-FU	Anticancer activity against human CCRF-CEM cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human CCRF-CEM cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay	[PMID: 29133046]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay	[PMID: 28525845]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay	[PMID: 27875779]
CFPAC-1	IC₅₀	41.221 μM Compound: 5-Fluorouracil	Cytotoxicity against human CFPAC-1 cells incubated for 24 hrs by MTT assay Cytotoxicity against human CFPAC-1 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
CHO	IC₅₀	12 μg/mL Compound: 5-fluorouracil	Cytotoxicity against CHO cells by MTT assay Cytotoxicity against CHO cells by MTT assay	[PMID: 29280630]
CNE	IC₅₀	15.07 μM Compound: 5-Fu	Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
CNE	IC₅₀	40.21 μM Compound: 5-FU	Cytotoxicity against human CNE cells after 48 hrs by MTT assay Cytotoxicity against human CNE cells after 48 hrs by MTT assay	[PMID: 24378217]
CNE	IC₅₀	45.1 μM Compound: 5-Fu	Cytotoxicity against human CNE cells after 48 hrs by MTT assay Cytotoxicity against human CNE cells after 48 hrs by MTT assay	[PMID: 24953029]
CNE-2	IC₅₀	13.1 μM Compound: 5-FU	Cytotoxicity against human CNE2 cells after 3 days by MTT assay Cytotoxicity against human CNE2 cells after 3 days by MTT assay	[PMID: 21144621]
CNE-2	IC₅₀	13.5 μM Compound: Fluorouracil	Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay	[PMID: 22200404]
CNE-2	IC₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay	[PMID: 22749192]
CNE-2	IC₅₀	17.2 μM Compound: 5-FU	Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay	[PMID: 22079378]
COLO 205	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
COLO 205	GI₅₀	0.15 μM Compound: 5-FU	Anticancer activity against human COLO 205 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human COLO 205 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
COLO 205	GI₅₀	0.15 μM Compound: 5-FU	Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
COLO 205	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
COLO 205	IC₅₀	1.9 μM Compound: 5-F	Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 28254697]
COLO 205	IC₅₀	1.9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human COLO205 cells by MTT assay Antiproliferative activity against human COLO205 cells by MTT assay	[PMID: 29798826]
COLO 205	IC₅₀	11.63 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs	[PMID: 18469809]
COLO 205	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
COLO 205	GI₅₀	2.8 μM Compound: 5FU	Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
COLO 205	IC₅₀	2.9 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) COLO205 cells by SRB assay Cytotoxicity against Homo sapiens (human) COLO205 cells by SRB assay	10.1007/s00044-010-9500-5
COLO 205	IC₅₀	21 μM Compound: 5-FU	Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 19939522]
COLO 205	IC₅₀	27.7 μM Compound: 5-FU	Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 30 mins by SRB assay Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 30 mins by SRB assay	[PMID: 30114660]
COLO 205	IC₅₀	3.39 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
COLO 205	EC₅₀	38.06 μM Compound: 5-FU	Antiproliferative activity against human COLO205 cells after 24 hrs by MTT assay Antiproliferative activity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 25198997]
COLO 205	IC₅₀	4.03 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 23352638]
COLO 205	IC₅₀	4.562 μg/mL Compound: 5-FU	Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 23548704]
COLO 205	IC₅₀	5.29 μM Compound: 5-FU	Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34170142]
COLO 205	IC₅₀	90 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
COLO 320	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human COLO320 cells after 48 hrs Antiproliferative activity against human COLO320 cells after 48 hrs	[PMID: 21458113]
COLO 320	IC₅₀	12.5 μM Compound: 5-FU	Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay	[PMID: 22955095]
COLO 320	IC₅₀	8.7 μM Compound: 5-FU	Antiproliferative activity against human COLO320 cells after 72 hrs Antiproliferative activity against human COLO320 cells after 72 hrs	[PMID: 21458113]
COLO 320DM	IC₅₀	2 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay	[PMID: 23792352]
COLO357	IC₅₀	2.05 μM Compound: 5-FU	Cytotoxicity against human Colo-357 cells by crystal violet staining Cytotoxicity against human Colo-357 cells by crystal violet staining	[PMID: 20930123]
Colon 26	IC₅₀	3.87 μM Compound: 5-Fluorouracil	Dark toxicity against human Colon 26 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Dark toxicity against human Colon 26 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 36561065]
Colon 26	IC₅₀	4.1 μM Compound: 5-Fluorouracil	Phototoxicity against human Colon 26 cells assessed as inhibition of cell growth preincubated for 24 hrs followed by compound washout with replacement of fresh medium and irradiation with 50 W LED light by MTT assay Phototoxicity against human Colon 26 cells assessed as inhibition of cell growth preincubated for 24 hrs followed by compound washout with replacement of fresh medium and irradiation with 50 W LED light by MTT assay	[PMID: 36561065]
COS-1	IC₅₀	110 μM Compound: 5-FU	Cytotoxicity against african green monkey COS1 cells after 24 hrs by MTT assay Cytotoxicity against african green monkey COS1 cells after 24 hrs by MTT assay	[PMID: 23202484]
CT26.WT	IC₅₀	5 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse CT26.WT cells by MTT assay Cytotoxicity against mouse CT26.WT cells by MTT assay	[PMID: 29280630]
CWR22R	IC₅₀	18.31 μM Compound: 5-FU	Antiproliferative activity against human 22Rv1 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human 22Rv1 cells assessed as cell growth inhibition by MTT assay	[PMID: 34000484]
CWR22R	IC₅₀	3.83 μM Compound: 5-fluorouracil	Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
DAN-G	IC₅₀	4.38 μM Compound: 5-FU	Cytotoxicity against human DAN-G cells by crystal violet staining Cytotoxicity against human DAN-G cells by crystal violet staining	[PMID: 20930123]
DLD-1	IC₅₀	11.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
DLD-1	EC₅₀	16.3 μM Compound: 5-FU	Antiproliferative activity against human DLD1 cells after 24 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 24 hrs by MTT assay	[PMID: 25198997]
DLD-1	IC₅₀	29.14 μM Compound: 5-Fu	Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay	[PMID: 24583355]
DLD-1	IC₅₀	33 μM Compound: 5-FU	Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay	[PMID: 30429977]
DLD-1	IC₅₀	33 μM Compound: 5-FU	Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay	[PMID: 30037494]
DLD-1	IC₅₀	7.38 μM Compound: 5-FU	Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay	[PMID: 15387639]
DMS-114	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human DMS114 cells after 48 hrs by SRB assay Growth inhibition of human DMS114 cells after 48 hrs by SRB assay	[PMID: 22512908]
DU-145	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
DU-145	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 21689869]
DU-145	GI₅₀	0.36 μM Compound: 5-FU	Anticancer activity against human DU-145 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human DU-145 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
DU-145	GI₅₀	0.36 μM Compound: 5-FU	Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
DU-145	GI₅₀	1 μg/mL Compound: 5FU	Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
DU-145	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human DU145 cells after 24 hrs by MTT assay Cytotoxicity against human DU145 cells after 24 hrs by MTT assay	[PMID: 24060486]
DU-145	IC₅₀	1.5 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 24 hrs by MTT assay Cytotoxicity against human DU145 cells after 24 hrs by MTT assay	[PMID: 24835633]
DU-145	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
DU-145	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
DU-145	IC₅₀	1.9 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against prostate cancer DU-145 cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer DU-145 cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer DU-145 cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer DU-145 cell line by sulforhodamine B assay	[PMID: 16005217]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate DU-145 cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate DU-145 cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
DU-145	IC₅₀	12.32 μM Compound: 5-Fu	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 22687745]
DU-145	GI₅₀	15.4 μM Compound: 5FU	Cytotoxicity against human DU145 cells after 48 hrs Cytotoxicity against human DU145 cells after 48 hrs	[PMID: 18798609]
DU-145	IC₅₀	2.18 μM Compound: 5-FU	Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay	[PMID: 28923381]
DU-145	IC₅₀	2.18 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 28431881]
DU-145	IC₅₀	2.19 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 20494492]
DU-145	IC₅₀	2.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
DU-145	IC₅₀	2.95 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) DU145 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) DU145 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
DU-145	IC₅₀	2.95 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) DU145 cells by MTT assay Cytotoxicity against Homo sapiens (human) DU145 cells by MTT assay	10.1007/s00044-010-9395-1
DU-145	GI₅₀	20 nM Compound: 5FU	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 23094992]
DU-145	IC₅₀	24.2 μM Compound: 5 Fluorouracil	Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
DU-145	IC₅₀	25.3 μM Compound: 5-Fu	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	[PMID: 30527868]
DU-145	IC₅₀	26.1 μM Compound: 5-Fu	Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27561718]
DU-145	IC₅₀	38 μM Compound: 5-Fu	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
DU-145	IC₅₀	39.17 μM Compound: 5-FU	Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
DU-145	IC₅₀	39.17 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 27397498]
DU-145	IC₅₀	39.17 μM Compound: 5-FU	Anticancer activity against human DU145 cells after 48 hrs by MTT assay Anticancer activity against human DU145 cells after 48 hrs by MTT assay	[PMID: 26413726]
DU-145	IC₅₀	4.8 μM Compound: 5-fluorouracil	Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
DU-145	IC₅₀	40.58 μM Compound: 5-FU	Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
DU-145	GI₅₀	5.82 μM Compound: 5-FU	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 28400235]
DU-145	IC₅₀	6.072 μM Compound: 5-Fluorouracil	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	[PMID: 26301558]
DU-145	IC₅₀	6.37 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 25870131]
DU-145	GI₅₀	9.37 μM Compound: 5-Fu	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 22512908]
E0771	IC₅₀	0.28 μM Compound: 5-Fu	Cytotoxicity against mouse E0771 cells after 3 days by SRB assay Cytotoxicity against mouse E0771 cells after 3 days by SRB assay	[PMID: 24704691]
EC9706	IC₅₀	0.32 μM Compound: 5-Fu	Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 23644193]
EC9706	IC₅₀	15.67 μM Compound: 5-Fu	Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 25707012]
EC9706	IC₅₀	20.3 μM Compound: 5-Fu	Antitumor activity against human EC9706 cells after 72 hrs by MTT assay Antitumor activity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 21486694]
EC9706	IC₅₀	23.26 μM Compound: 5-Fluorouracil	Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay	[PMID: 28119200]
EC9706	IC₅₀	4.7 μM Compound: 5-Fu	Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
EC9706	IC₅₀	5.13 μM Compound: 5-Fu	Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 29475156]
EC9706	IC₅₀	8.07 μM Compound: 5-Fu	Anticancer activity against human EC9706 cells after 72 hrs by MTT assay Anticancer activity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 25001482]
EC9706	IC₅₀	9.45 μM Compound: 5-Fu	Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay	[PMID: 24835817]
ECa-109 cell line	IC₅₀	10.3 μM Compound: 5-FU	Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 28038329]
ECa-109 cell line	IC₅₀	10.3 μM Compound: 5-FU	Cytotoxicity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27423479]
ECa-109 cell line	IC₅₀	10.59 μM Compound: 5-Fu	Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay	[PMID: 27771599]
ECa-109 cell line	IC₅₀	10.61 μM Compound: 5-Fu	Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
ECa-109 cell line	IC₅₀	10.61 μM Compound: 5-Fu	Cytotoxicity against human EC109 cells after 72 hrs by MTT assay Cytotoxicity against human EC109 cells after 72 hrs by MTT assay	[PMID: 23792764]
ECa-109 cell line	IC₅₀	10.81 μM Compound: 5-Fu	Cytotoxicity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
ECa-109 cell line	IC₅₀	11.1 μM Compound: 5-Fu	Antiproliferative activity against human EC109 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human EC109 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34455358]
ECa-109 cell line	IC₅₀	11.37 μM Compound: 5-FU	Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
ECa-109 cell line	IC₅₀	11.61 μM Compound: 5-Fu	Anticancer activity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
ECa-109 cell line	IC₅₀	15.9 μM Compound: 5-Fu	Cytotoxicity against human EC109 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human EC109 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
ECa-109 cell line	IC₅₀	21.21 μM Compound: 5-FU	Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 31740251]
ECa-109 cell line	IC₅₀	24.14 μM Compound: 5-Fu	Cytotoxicity against human EC109 cells after 72 hrs by MTT assay Cytotoxicity against human EC109 cells after 72 hrs by MTT assay	[PMID: 24798098]
ECa-109 cell line	IC₅₀	25.99 μM Compound: 5-FU	Cytotoxicity against human EC109 cells assessed as growth inhibition by MTT assay Cytotoxicity against human EC109 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
ECa-109 cell line	IC₅₀	3.17 μM Compound: 5-Fu	Antiproliferative activity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
ECa-109 cell line	IC₅₀	3.34 μM Compound: 5-Fu	Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
ECa-109 cell line	IC₅₀	30.25 μM Compound: 5-Fluorouracil	Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay	[PMID: 28119200]
ECa-109 cell line	IC₅₀	5.01 μM Compound: 5-FU	Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay	[PMID: 28759876]
ECa-109 cell line	IC₅₀	56.2 μM Compound: 5-FU	Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay	[PMID: 28763643]
ECa-109 cell line	IC₅₀	6.02 μM Compound: 5-Fu	Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay	[PMID: 29475156]
ECa-109 cell line	IC₅₀	6.21 μM Compound: 5-Fu	Antiproliferative activity against human EC109 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human EC109 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
ECa-109 cell line	IC₅₀	6.21 μM Compound: 5-FU	Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay	[PMID: 28863355]
ECa-109 cell line	IC₅₀	6.21 μM Compound: 5-FU	Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay	[PMID: 28838695]
ECa-109 cell line	IC₅₀	6.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human EC109 cells by MTT assay Antiproliferative activity against human EC109 cells by MTT assay	[PMID: 31546197]
Ehrlich	IC₅₀	0.38 μM Compound: 5-FU	Antitumor activity against mouse EAC cells by trypan blue exclusion assay Antitumor activity against mouse EAC cells by trypan blue exclusion assay	10.1007/s00044-013-0859-y
Ehrlich	IC₅₀	1.5 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells assessed as cell viability using trypan blue staining after 2 hrs by hemocytometer analysis Cytotoxicity against mouse EAC cells assessed as cell viability using trypan blue staining after 2 hrs by hemocytometer analysis	[PMID: 21353349]
Ehrlich	IC₅₀	14.3 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay	[PMID: 24534537]
Ehrlich	IC₅₀	14.6 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method	[PMID: 25261825]
Ehrlich	IC₅₀	15.4 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay	[PMID: 25261825]
Ehrlich	IC₅₀	16.3 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay	[PMID: 24534537]
Ehrlich	IC₅₀	16.3 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by MTT method Cytotoxicity against mouse EAC cells after 48 hrs by MTT method	[PMID: 25261825]
Ehrlich	IC₅₀	16.4 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay	[PMID: 24534537]
Ehrlich	CC₅₀	37.36 μM Compound: 5-FU	Cytotoxicity against mouse EAC cell assessed as reduction in cell viability incubated for 3 hrs by tryphan blue dye based assay Cytotoxicity against mouse EAC cell assessed as reduction in cell viability incubated for 3 hrs by tryphan blue dye based assay	[PMID: 33540356]
Ehrlich	ED₅₀	38.6 ug Compound: 5-FU	Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis	[PMID: 23022735]
Ehrlich	ED₅₀	58 uL Compound: 5FU	Antitumor activity against mouse EAC cells tansplanted in Swiss albino mouse assessed as dead cells at 50 to 250 mg/kg/day, ip by tyrpan blue assay Antitumor activity against mouse EAC cells tansplanted in Swiss albino mouse assessed as dead cells at 50 to 250 mg/kg/day, ip by tyrpan blue assay	[PMID: 19527933]
Ehrlich	ED₅₀	63 μg/cm³ Compound: 5-FU	In vitro antitumor activity against Mus musculus (mouse) Ehrlich ascites cell assessed as dead tumor cells by trypan blue exclusion test In vitro antitumor activity against Mus musculus (mouse) Ehrlich ascites cell assessed as dead tumor cells by trypan blue exclusion test	10.1007/s00044-012-0336-z
Ehrlich	IC₅₀	9.2 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
Ehrlich	IC₅₀	9.6 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
Ehrlich	CC₅₀	90.55 μM Compound: 5-FU	Growth inhibition of EAC cells after 3 hrs Growth inhibition of EAC cells after 3 hrs	[PMID: 17239491]
Ehrlich	ED₅₀	96.3 mM Compound: 5-flu	Cytotoxicity against Mus musculus (mouse) EAC assessed as cell viability by trypan blue exclusion assay Cytotoxicity against Mus musculus (mouse) EAC assessed as cell viability by trypan blue exclusion assay	10.1007/s00044-009-9199-3
Ehrlich	IC₅₀	97.3 ug Compound: 5-FU	Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis	[PMID: 23022735]
EKVX	GI₅₀	61.8 μM Compound: 5-FU	Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
Fibroblast	IC₅₀	> 50 μM Compound: 5-FU	Cytotoxicity against human skin fibroblast cells incubated for 72 hrs by MTT assay Cytotoxicity against human skin fibroblast cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
Fibroblast	IC₅₀	11 μM Compound: 5-FU	Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test	[PMID: 21530016]
FM3A	IC₅₀	0.18 μM Compound: 5-FU	Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis	[PMID: 21330014]
GES1	IC₅₀	> 100 μM Compound: 5-Fu	Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 35191714]
GES1	IC₅₀	10.21 μM Compound: 5-FU	Cytotoxicity against human GES1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
GES1	IC₅₀	12.51 μM Compound: 5-Fu	Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
GES1	IC₅₀	12.51 μM Compound: 5-Fu	Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay	[PMID: 29635165]
GES1	IC₅₀	13.75 μM Compound: 5-FU	Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
GES1	IC₅₀	19.27 μM Compound: 5-FU	Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 34302974]
GES1	IC₅₀	2.37 μM Compound: 5-Fu	Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
GES1	IC₅₀	2.45 μM Compound: 5-Fu	Antiproliferative activity against human GES1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human GES1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
GES1	IC₅₀	3.69 μM Compound: 5-FU	Antiproliferative activity against human GES-1 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human GES-1 cells incubated for 72 hrs by MTT assay	[PMID: 31404863]
GES1	IC₅₀	30.9 μM Compound: 5-Fu	Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay	[PMID: 25462264]
GES1	IC₅₀	38.5 μM Compound: 5-Fu	Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
GES1	IC₅₀	49.6 μM Compound: 5-FU	Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 35286954]
GES1	IC₅₀	7.22 μM Compound: 5-Fu	Cytotoxicity against human GES-1 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human GES-1 cells assessed as cell growth inhibition after 72 hrs by MTT assay	10.1039/C6MD00169F
GES1	IC₅₀	78.4 μM Compound: 5-FU	Toxicity in human GES1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Toxicity in human GES1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
GES1	IC₅₀	8.59 μM Compound: 5-FU	Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759876]
GES1	IC₅₀	9.02 μM Compound: 5-FU	Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay	[PMID: 28863355]
GTL 16 cell line	IC₅₀	0.84 μM Compound: 5-FU	Antitumor activity against human GTL 16 cell line assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human GTL 16 cell line assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
H4	CC₅₀	3843.8 μM Compound: 5-Fu	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 18037195]
H4	CC₅₀	3843.8 μM Compound: 5FU	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 17555969]
H4	CC₅₀	3843.8 μM Compound: 5FU	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 17548129]
H4	CC₅₀	3843.8 μM Compound: 5-FU	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 17337193]
H69AR	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human H69AR cells after 48 hrs by SRB assay Growth inhibition of human H69AR cells after 48 hrs by SRB assay	[PMID: 22512908]
HaCaT	IC₅₀	0.3 μM Compound: 5-Fluorouracil	Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay	[PMID: 22405290]
HaCaT	IC₅₀	0.4 μM Compound: 5-FU	Growth inhibition of human HaCaT cells after 72 hrs by MTT assay Growth inhibition of human HaCaT cells after 72 hrs by MTT assay	[PMID: 18640746]
HaCaT	IC₅₀	15.26 μM Compound: 5-Fluorouracil	Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
HaCaT	IC₅₀	16.15 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay	[PMID: 27092413]
HBL-100	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HBL100 cells by MTT assay Antiproliferative activity against human HBL100 cells by MTT assay	[PMID: 31546197]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Antiproliferative activity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay	[PMID: 28728108]
HBL-100	GI₅₀	5.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HCC 2998	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCC 2998	GI₅₀	0.05 μM Compound: 5-FU	Anticancer activity against human HCC 2998 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HCC 2998 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HCC 2998	GI₅₀	0.05 μM Compound: 5-FU	Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HCC 2998	IC₅₀	12.6 μM Compound: 5-FU	Cytotoxicity against human HCC 2998 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay Cytotoxicity against human HCC 2998 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay	[PMID: 35182815]
HCC 2998	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCC 2998	IC₅₀	5.75 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
HCC1937	IC₅₀	25.94 μM Compound: 5-FU	Antitumor activity against human HCC1937 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human HCC1937 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
HCCLM3	IC₅₀	1.84 mM Compound: 5-FU	Antiproliferative activity against human HCCLM3 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Antiproliferative activity against human HCCLM3 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 28073674]
HCT-116	GI₅₀	> 10 μM Compound: 4; 5-FU	Antiproliferative activity against human HCT-116 cells measured after 48 hrs by SRB assay Antiproliferative activity against human HCT-116 cells measured after 48 hrs by SRB assay	[PMID: 32683166]
HCT-116	EC₅₀	> 1000 μM Compound: 5-FU	Antiproliferative activity against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34688013]
HCT-116	EC₅₀	> 1000 μM Compound: 5-FU	Reversal of 5-FU resistance against human HCT-116 cells overexpressing DPD assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay Reversal of 5-FU resistance against human HCT-116 cells overexpressing DPD assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay	[PMID: 34411894]
HCT-116	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-116	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 24 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 24 hrs by MTT assay	[PMID: 26922233]
HCT-116	EC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 25198997]
HCT-116	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26922233]
HCT-116	IC₅₀	0.041 mM Compound: 5-Fluorouracil	Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
HCT-116	IC₅₀	0.0462 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 72 hr by MTT assay	10.1007/s00044-012-0181-0
HCT-116	GI₅₀	0.22 μM Compound: 5-FU	Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HCT-116	GI₅₀	0.22 μM Compound: 5-FU	Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HCT-116	ED₅₀	0.48 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells by MTT assay Cytotoxicity against human HCT116 cells by MTT assay	[PMID: 11908984]
HCT-116	IC₅₀	0.5 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 25066282]
HCT-116	EC₅₀	0.5 μM Compound: 1; 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay	[PMID: 34979089]
HCT-116	IC₅₀	0.54 μM Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay	[PMID: 30660827]
HCT-116	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-116	IC₅₀	1.93 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
HCT-116	IC₅₀	1.93 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 20494492]
HCT-116	IC₅₀	1.93 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HCT116 cells by MTT assay Cytotoxicity against Homo sapiens (human) HCT116 cells by MTT assay	10.1007/s00044-010-9395-1
HCT-116	IC₅₀	10.05 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 24953029]
HCT-116	IC₅₀	10.54 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24819956]
HCT-116	IC₅₀	10.81 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
HCT-116	IC₅₀	11.29 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 29316536]
HCT-116	IC₅₀	11.56 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 30318440]
HCT-116	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
HCT-116	IC₅₀	12.31 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
HCT-116	IC₅₀	13 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
HCT-116	IC₅₀	13.8 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32682200]
HCT-116	IC₅₀	13.9 μM Compound: 1; 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay	[PMID: 33819035]
HCT-116	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-116	IC₅₀	14.9 μM Compound: 1; 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 33819035]
HCT-116	IC₅₀	15.38 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
HCT-116	IC₅₀	15.52 μM Compound: 5-FU	Cytotoxicity against human HCT116 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
HCT-116	IC₅₀	17.25 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 29486954]
HCT-116	IC₅₀	18.4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 30108969]
HCT-116	IC₅₀	18.4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
HCT-116	IC₅₀	18.7 μM Compound: 5FU	Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HCT-116	IC₅₀	19.2 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 48 hr by MTT assay Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 48 hr by MTT assay	10.1007/s00044-012-0461-8
HCT-116	IC₅₀	19.2 μM Compound: 5-FU	Anticancer activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay Anticancer activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay	10.1007/s00044-012-0240-6
HCT-116	IC₅₀	19.27 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay	[PMID: 34715305]
HCT-116	IC₅₀	2 mM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27847140]
HCT-116	IC₅₀	2.3 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 26854375]
HCT-116	IC₅₀	2.5 μM Compound: 5-FU	Growth inhibition of human HCT116 cells after 72 hrs by MTS assay Growth inhibition of human HCT116 cells after 72 hrs by MTS assay	[PMID: 27704811]
HCT-116	IC₅₀	2.6 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 19743863]
HCT-116	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs	[PMID: 17548198]
HCT-116	IC₅₀	20.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 31471102]
HCT-116	IC₅₀	201 μg/mL Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
HCT-116	IC₅₀	21.54 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36269639]
HCT-116	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 24565905]
HCT-116	IC₅₀	24.58 μM Compound: 5-FU	Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
HCT-116	IC₅₀	24.8 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
HCT-116	IC₅₀	26.14 μM Compound: 5-Fu	Anticancer activity against human HCT116 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against human HCT116 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
HCT-116	IC₅₀	26.2 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28400238]
HCT-116	IC₅₀	26042.5 nM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 32203786]
HCT-116	IC₅₀	27.76 μM Compound: 5-Fu	Growth inhibition against human HCT116 cells after 48 hrs by MTT assay Growth inhibition against human HCT116 cells after 48 hrs by MTT assay	[PMID: 23999046]
HCT-116	IC₅₀	27.76 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 23558238]
HCT-116	IC₅₀	27.8 μM Compound: 5-FU	Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 26922233]
HCT-116	IC₅₀	29.2 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28073676]
HCT-116	IC₅₀	29.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 27503679]
HCT-116	IC₅₀	29.5 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 29232583]
HCT-116	IC₅₀	29.58 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
HCT-116	IC₅₀	3.03 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20163895]
HCT-116	IC₅₀	3.24 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 23685571]
HCT-116	IC₅₀	3.56 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay	[PMID: 23305919]
HCT-116	IC₅₀	31.72 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 22483608]
HCT-116	IC₅₀	32.26 μM Compound: 5-FU	Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
HCT-116	IC₅₀	36.2 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
HCT-116	IC₅₀	36.4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 23067549]
HCT-116	IC₅₀	37.22 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
HCT-116	IC₅₀	37.6 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 30108895]
HCT-116	IC₅₀	38.3 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28110871]
HCT-116	IC₅₀	38.3 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 30142612]
HCT-116	IC₅₀	38.3 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HCT-116	IC₅₀	4 μM Compound: 5-FU	Antitumor activity against human HCT116 cells after 24 hrs by MTT assay Antitumor activity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 20211564]
HCT-116	IC₅₀	4 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
HCT-116	IC₅₀	4 μM Compound: 5-Fluorouracil	Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 22405290]
HCT-116	IC₅₀	4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 22130132]
HCT-116	IC₅₀	4 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 29326016]
HCT-116	IC₅₀	4.16 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 28458133]
HCT-116	IC₅₀	4.3 μM Compound: 5-FU	Antiproliferative activity in human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity in human HCT116 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
HCT-116	IC₅₀	4.3 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells harboring p53 knock out gene assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-116 cells harboring p53 knock out gene assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-116	IC₅₀	4.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells expressing wild type p53 incubated for 72 hrs by MTS assay Cytotoxicity against human HCT116 cells expressing wild type p53 incubated for 72 hrs by MTS assay	[PMID: 31158748]
HCT-116	IC₅₀	4.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 26222449]
HCT-116	IC₅₀	4.52 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 23644215]
HCT-116	IC₅₀	4.6 μM Compound: 5-FU	Anticancer activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Anticancer activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33940466]
HCT-116	IC₅₀	4.69 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells deficient in p53 incubated for 72 hrs by MTS assay Cytotoxicity against human HCT116 cells deficient in p53 incubated for 72 hrs by MTS assay	[PMID: 31158748]
HCT-116	IC₅₀	4.8 μg/mL Compound: 5-Fu	Anticancer activity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
HCT-116	IC₅₀	4.89 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
HCT-116	IC₅₀	4.9 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
HCT-116	IC₅₀	4.93 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay	[PMID: 15387639]
HCT-116	IC₅₀	41.9 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28532669]
HCT-116	IC₅₀	44.06 μM Compound: 2; 5-FU	Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
HCT-116	GI₅₀	5.47 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 28716495]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 27575478]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 26703795]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells by MTS assay Cytotoxicity against human HCT116 cells by MTS assay	[PMID: 29843103]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 23665106]
HCT-116	IC₅₀	5.78 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 24378217]
HCT-116	IC₅₀	5.78 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells after 72 hrs by MTT assay	[PMID: 35609396]
HCT-116	IC₅₀	53.84 μM Compound: 2; 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 29202398]
HCT-116	IC₅₀	56.96 μM Compound: 5-Fuorouracil	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 27017265]
HCT-116	IC₅₀	6 μg/mL Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 22154835]
HCT-116	IC₅₀	6 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 25462277]
HCT-116	IC₅₀	6 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 22409771]
HCT-116	IC₅₀	6.1 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
HCT-116	IC₅₀	6.36 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
HCT-116	IC₅₀	6.5 μM Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells after 48 hrs by CellTiter-Glo assay Cytotoxicity against human HCT116 cells after 48 hrs by CellTiter-Glo assay	[PMID: 31999116]
HCT-116	IC₅₀	6.86 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
HCT-116	IC₅₀	6.86 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
HCT-116	IC₅₀	63.9 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human HCT116 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
HCT-116	IC₅₀	68.71 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay	[PMID: 27287368]
HCT-116	IC₅₀	7.38 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34170142]
HCT-116	IC₅₀	7.77 μM Compound: 5-FU	Antitumor activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
HCT-116	IC₅₀	8.32 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24211021]
HCT-116	IC₅₀	8.62 μM Compound: 5-FU	Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay	[PMID: 28923381]
HCT-116	IC₅₀	8.638 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 29223717]
HCT-116	GI₅₀	8.8 nM Compound: 5FU	Growth inhibition of human HCT116 cells after 48 hrs by SRB assay Growth inhibition of human HCT116 cells after 48 hrs by SRB assay	[PMID: 23094992]
HCT-116	IC₅₀	84.9 μM Compound: 2; 5-FU	Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay	[PMID: 27322756]
HCT-116	GI₅₀	9.51 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
HCT-116	IC₅₀	9.88 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
HCT-116	GI₅₀	9.9 μM Compound: 5-Fu	Growth inhibition of human HCT116 cells after 48 hrs by SRB assay Growth inhibition of human HCT116 cells after 48 hrs by SRB assay	[PMID: 22512908]
HCT-116	IC₅₀	91.73 μM Compound: 5-FU	Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HCT-15	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-15	GI₅₀	0.11 μM Compound: 5-FU	Anticancer activity against human HCT-15 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HCT-15 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HCT-15	GI₅₀	0.11 μM Compound: 5-FU	Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HCT-15	IC₅₀	10.86 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
HCT-15	IC₅₀	11.87 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay	[PMID: 30318440]
HCT-15	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-15	IC₅₀	18.24 μM Compound: 5-FU	Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
HCT-15	GI₅₀	21 μM Compound: 5-Fu	Growth inhibition of human HCT15 cells after 48 hrs by SRB assay Growth inhibition of human HCT15 cells after 48 hrs by SRB assay	[PMID: 22512908]
HCT-15	GI₅₀	21.1 nM Compound: 5FU	Growth inhibition of human HCT15 cells after 48 hrs by SRB assay Growth inhibition of human HCT15 cells after 48 hrs by SRB assay	[PMID: 23094992]
HCT-15	IC₅₀	3.6 μM Compound: 5-fluorouracil	Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HCT-15	IC₅₀	33.68 μM Compound: 5-fluorouracil	Antiproliferative activity against human HCT-15 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human HCT-15 cells assessed as cell growth inhibition by MTT assay	[PMID: 31945642]
HCT-15	IC₅₀	4.5 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 24910974]
HCT-15	IC₅₀	45.01 μM Compound: 5-FU	Growth inhibition of human HCT15 cells after 24 hrs by MTT assay Growth inhibition of human HCT15 cells after 24 hrs by MTT assay	[PMID: 28011220]
HCT-15	IC₅₀	45.01 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay	[PMID: 23202484]
HCT-15	IC₅₀	48 μM Compound: 5-FU	Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
HCT-15	IC₅₀	6.61 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
HCT-15	IC₅₀	7.53 μM Compound: 5-Fu	Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay	[PMID: 29174813]
HCT-15	IC₅₀	7.53 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay	[PMID: 30677614]
HCT-15	IC₅₀	8.24 μM Compound: 5-FU	Anticancer activity against human HCT-15 cells incubated for 72 hrs by MTT assay Anticancer activity against human HCT-15 cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
HCT-8	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HCT8 after 24 hrs by MTT assay Cytotoxicity against human HCT8 after 24 hrs by MTT assay	[PMID: 19338315]
HCT-8	IC₅₀	0.54 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human HCT8 cells by MTT assay Cytotoxicity against human HCT8 cells by MTT assay	[PMID: 18205316]
HCT-8	IC₅₀	0.91 μM Compound: 5-FU	Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25675144]
HCT-8	IC₅₀	2.2 μM Compound: 5-FU	Cytotoxicity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-8	IC₅₀	28.9 μM Compound: 5-FU	Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 30429977]
HCT-8	IC₅₀	28.9 μM Compound: 5-FU	Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 30037494]
HCT-8	IC₅₀	3.54 μM Compound: 5-FU	Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
HCT-8	IC₅₀	32.31 μM Compound: 5-FU	Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
HCT-8	IC₅₀	36.638 μM Compound: 5-FU	Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25675144]
HCT-8	IC₅₀	4.2 μM Compound: 5-Fu	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 16499317]
HCT-8	IC₅₀	47 μM Compound: 5-FU	Cytotoxicity against 5-FU resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against 5-FU resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-8	IC₅₀	5.38 μM Compound: 5-Fu	Cytotoxicity against human HCT8 cells by MTT method Cytotoxicity against human HCT8 cells by MTT method	[PMID: 23164710]
HCT-8	IC₅₀	6.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 26227777]
HCT-8	IC₅₀	6.92 μM Compound: 5-Fu	Antiproliferative activity against human HCT8 cells by MTT assay Antiproliferative activity against human HCT8 cells by MTT assay	[PMID: 24095094]
HEK293	IC₅₀	19.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HEK293 cells by MTT assay Antiproliferative activity against human HEK293 cells by MTT assay	[PMID: 29798826]
HEK293	IC₅₀	2.15 μM Compound: 5-Florouracil	Cytotoxicity against Homo sapiens (human) HEK293 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay Cytotoxicity against Homo sapiens (human) HEK293 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay	10.1007/s00044-012-0260-2
HEK293	IC₅₀	40 μM Compound: 5 Fluorouracil	Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
HEK293	IC₅₀	41.01 μM Compound: 5-Fu	Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay	[PMID: 35609396]
HEK293	IC₅₀	42.9 μM Compound: 5-FU	Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay	[PMID: 22093761]
HEK293	IC₅₀	48.7 μM Compound: 5-FU	Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay	[PMID: 25198997]
HEK293	IC₅₀	79.32 μM Compound: 5-FU	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 32203786]
HEK-293T	IC₅₀	> 100 μM Compound: 5-FU	Growth inhibition of HEK293T cells after 24 hrs by MTT assay Growth inhibition of HEK293T cells after 24 hrs by MTT assay	[PMID: 28011220]
HEL	IC₅₀	15.98 μM Compound: 5-fluorouracil	Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
HEL	IC₅₀	32.27 μM Compound: 2; 5-FU	Antiproliferative activity against human HEL cells after 48 hrs by MTT assay Antiproliferative activity against human HEL cells after 48 hrs by MTT assay	[PMID: 27322756]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient HeLa cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient HeLa cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 26617970]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 21689869]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human HeLa cells after 72 hrs Antiproliferative activity against p53 deficient human HeLa cells after 72 hrs	[PMID: 18469809]
HeLa	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
HeLa	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
HeLa	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
HeLa	IC₅₀	0.04 mg/mL Compound: 5-Fu	Cytotoxicity against human HeLa cells after 3 days MTT assay Cytotoxicity against human HeLa cells after 3 days MTT assay	[PMID: 22796042]
HeLa	EC₅₀	0.23 μM Compound: 5-fluorouracil	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 12027739]
HeLa	IC₅₀	0.23 μM Compound: 1, 5-FU	Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting	[PMID: 21892829]
HeLa	IC₅₀	0.28 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 22959518]
HeLa	IC₅₀	0.44 μM Compound: 5-Fluoro uracil	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 19689125]
HeLa	IC₅₀	0.45 μM Compound: 5-FU	Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis	[PMID: 21330014]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis	[PMID: 22405290]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method	[PMID: 27750154]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method	[PMID: 24906510]
HeLa	IC₅₀	0.54 μM Compound: 5FU	Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay	[PMID: 24631358]
HeLa	IC₅₀	0.54 μM Compound: 1, 5-FU	Cytostatic activity against human HeLa cells after 72 hrs by cell counting Cytostatic activity against human HeLa cells after 72 hrs by cell counting	[PMID: 21892829]
HeLa	IC₅₀	0.57 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis	[PMID: 21232828]
HeLa	IC₅₀	0.77 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 18440233]
HeLa	IC₅₀	0.8 μg/mL Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 23994872]
HeLa	IC₅₀	0.887 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24021891]
HeLa	IC₅₀	1.01 μg/mL Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by SRB assay Cytotoxicity against human HeLa cells after 48 hrs by SRB assay	[PMID: 19932530]
HeLa	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24060486]
HeLa	IC₅₀	1.28 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 23352638]
HeLa	IC₅₀	1.3 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24835633]
HeLa	IC₅₀	1.4 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 22011319]
HeLa	IC₅₀	1.4 μM Compound: 5-F	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 28254697]
HeLa	IC₅₀	1.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
HeLa	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
HeLa	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
HeLa	IC₅₀	1.8 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
HeLa	IC₅₀	1.8 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
HeLa	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 29798826]
HeLa	IC₅₀	1.86 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28431881]
HeLa	IC₅₀	1.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
HeLa	IC₅₀	1.94 μM Compound: 5-FU	Antitumor activity against human HeLa cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human HeLa cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
HeLa	IC₅₀	10 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 20405881]
HeLa	IC₅₀	10 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19919065]
HeLa	IC₅₀	10 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19795843]
HeLa	IC₅₀	10 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19618920]
HeLa	GI₅₀	10 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19572613]
HeLa	IC₅₀	10.31 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21524829]
HeLa	IC₅₀	10.36 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 22801644]
HeLa	IC₅₀	10.72 μg/mL Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
HeLa	IC₅₀	10.72 μM Compound: 5-FU	Cytotoxicity against human HeLa assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
HeLa	IC₅₀	10.75 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 30318440]
HeLa	IC₅₀	110.16 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 21962523]
HeLa	IC₅₀	12 μM Compound: 5-Fu	Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
HeLa	IC₅₀	12.3 μM Compound: 5-FU	Anticancer activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Anticancer activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33940466]
HeLa	IC₅₀	12.7 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
HeLa	IC₅₀	120.4 μM Compound: 5-FU	Cytotoxicity in human HeLa cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human HeLa cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
HeLa	IC₅₀	13.45 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25506718]
HeLa	IC₅₀	13.9 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay	[PMID: 28488862]
HeLa	IC₅₀	13.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 72 hrs by WST-8 assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 72 hrs by WST-8 assay	[PMID: 33383442]
HeLa	IC₅₀	13.9 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells incubated for 72 hrs by WST-8 assay Cytotoxicity against human HeLa cells incubated for 72 hrs by WST-8 assay	[PMID: 32125158]
HeLa	IC₅₀	132.99 μM Compound: 2; 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 27322756]
HeLa	IC₅₀	14.78 μM Compound: 5-FU	Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 23313635]
HeLa	IC₅₀	14.93 μM Compound: 5-Fluoruracil	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 22555152]
HeLa	IC₅₀	142.6 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23356786]
HeLa	GI₅₀	15 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
HeLa	GI₅₀	15 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay	[PMID: 28728108]
HeLa	GI₅₀	15 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
HeLa	IC₅₀	15.02 μM Compound: 5-FLU	Cytotoxicity against human HeLa cells assessed as growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as growth inhibition by MTT assay	[PMID: 32331934]
HeLa	IC₅₀	15.5 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
HeLa	IC₅₀	15.99 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 22687745]
HeLa	IC₅₀	16 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 3 days by MTT assay Antiproliferative activity against human HeLa cells after 3 days by MTT assay	[PMID: 18424155]
HeLa	IC₅₀	16.1 μM Compound: 5-FU	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 21515044]
HeLa	IC₅₀	16.32 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 22182926]
HeLa	IC₅₀	16.32 μM Compound: 5-Fu	Growth inhibition of human HeLa cells after 48 hrs by MTT assay Growth inhibition of human HeLa cells after 48 hrs by MTT assay	[PMID: 23353737]
HeLa	IC₅₀	16.32 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay	[PMID: 22579780]
HeLa	IC₅₀	16.52 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23920246]
HeLa	IC₅₀	17.21 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay	[PMID: 27542307]
HeLa	IC₅₀	17.21 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay	[PMID: 26786698]
HeLa	IC₅₀	18.1 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
HeLa	GI₅₀	19 μM Compound: 5-FU	Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HeLa	IC₅₀	2.3 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24547794]
HeLa	IC₅₀	2.6 μM Compound: 5-FU	Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting	[PMID: 25435471]
HeLa	IC₅₀	2.78 μM Compound: FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24941129]
HeLa	IC₅₀	2.9 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 28838694]
HeLa	IC₅₀	20.4 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human HeLa cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
HeLa	IC₅₀	20.6 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
HeLa	IC₅₀	23.33 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24953029]
HeLa	IC₅₀	24.34 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
HeLa	IC₅₀	26.18 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HeLa	IC₅₀	28 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay	[PMID: 29489361]
HeLa	IC₅₀	28.2 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27561718]
HeLa	IC₅₀	28.22 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
HeLa	IC₅₀	3.2 μg/mL Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
HeLa	IC₅₀	3.25 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT method Antiproliferative activity against human HeLa cells after 48 hrs by MTT method	[PMID: 23018096]
HeLa	IC₅₀	3.4 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 23792763]
HeLa	IC₅₀	3.82 μg/mL Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 29100732]
HeLa	IC₅₀	30.2 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 29305189]
HeLa	GI₅₀	30.21 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24934992]
HeLa	IC₅₀	30.21 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 30007564]
HeLa	IC₅₀	30.71 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay	[PMID: 36089111]
HeLa	EC₅₀	31.02 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 21889345]
HeLa	IC₅₀	32.1 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 34883453]
HeLa	IC₅₀	35.34 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 25151580]
HeLa	IC₅₀	35.34 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24378217]
HeLa	IC₅₀	36.53 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 25462253]
HeLa	IC₅₀	4 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 3 days by MTT assay Cytotoxicity against human HeLa cells after 3 days by MTT assay	[PMID: 21612935]
HeLa	IC₅₀	4 μM Compound: 5-FU	Growth inhibition of human HeLa cells after 72 hrs by MTT assay Growth inhibition of human HeLa cells after 72 hrs by MTT assay	[PMID: 18640746]
HeLa	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 31546197]
HeLa	IC₅₀	4.6 μM Compound: 5-Fluorouracil	Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
HeLa	IC₅₀	4.71 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
HeLa	IC₅₀	4.9 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 24910974]
HeLa	IC₅₀	41.46 μM Compound: 5-Fu	Antitumor activity against human HeLa cells after 72 hrs by MTT assay Antitumor activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21486694]
HeLa	IC₅₀	42.74 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
HeLa	IC₅₀	43 μM Compound: 5-fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 22304344]
HeLa	IC₅₀	43.71 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay	[PMID: 26703795]
HeLa	IC₅₀	43.71 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 23665106]
HeLa	IC₅₀	5.3 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
HeLa	IC₅₀	5.7 μg/mL Compound: 5-Fu	Anticancer activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
HeLa	IC₅₀	5.78 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
HeLa	IC₅₀	5.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay	[PMID: 25919052]
HeLa	IC₅₀	5.8 μM Compound: 5-FU	Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay	[PMID: 27311895]
HeLa	IC₅₀	50 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 31057737]
HeLa	IC₅₀	56.5 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay	10.1039/C6MD00234J
HeLa	IC₅₀	57.17 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay	[PMID: 27287368]
HeLa	IC₅₀	6.23 μM Compound: FUra	Cytotoxicity against human HeLa cells after 72 hrs by SRB assay Cytotoxicity against human HeLa cells after 72 hrs by SRB assay	[PMID: 27073055]
HeLa	IC₅₀	6.23 μM Compound: FUra	Cytotoxicity against human HeLa cells after 72 hrs by SRB assay Cytotoxicity against human HeLa cells after 72 hrs by SRB assay	[PMID: 23867603]
HeLa	IC₅₀	6.23 μM Compound: FUra	Cytotoxicity against human HeLa cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human HeLa cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
HeLa	IC₅₀	6.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay	[PMID: 26606140]
HeLa	IC₅₀	62.2 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay	[PMID: 28152430]
HeLa	IC₅₀	63.4 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23067549]
HeLa	IC₅₀	64.2 μM Compound: 5-Fu	Antitumor activity against human HeLa cells by MTT assay Antitumor activity against human HeLa cells by MTT assay	[PMID: 20171096]
HeLa	IC₅₀	66.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
HeLa	IC₅₀	7 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 29908443]
HeLa	IC₅₀	7.34 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 2 days by MTT assay Cytotoxicity against human HeLa cells after 2 days by MTT assay	[PMID: 24767839]
HeLa	IC₅₀	7.34 μM Compound: 5-Fu	Growth inhibition against human HeLa cells after 48 hrs by MTT assay Growth inhibition against human HeLa cells after 48 hrs by MTT assay	[PMID: 23999046]
HeLa	IC₅₀	7.34 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23558238]
HeLa	EC₅₀	79.79 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 20409617]
HeLa	IC₅₀	8.317 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 26301558]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 29133046]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 28525845]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 27875779]
HeLa	IC₅₀	8.93 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
HeLa	IC₅₀	80.48 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24565905]
HeLa	IC₅₀	82.2 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay	[PMID: 22244588]
HeLa	IC₅₀	82.27 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
HeLa	IC₅₀	9.02 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28363444]
HeLa	IC₅₀	9.09 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 25529742]
HeLa	IC₅₀	9.5 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23002924]
HeLa	IC₅₀	9.7 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 20494492]
HeLa	IC₅₀	9.7 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay	10.1007/s00044-010-9395-1
HeLa S3	ED₅₀	2.47 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HeLaS3 cells after 3 days by trypan blue exclusion technique Cytotoxicity against human HeLaS3 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
HeLa S3	IC₅₀	5.4 μM Compound: Fluorouracil	Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay	[PMID: 15387656]
HeLa S3	IC₅₀	5.4 μM Compound: fluorouracil	Cytotoxicity against human HeLaS3 cells by WST1 assay Cytotoxicity against human HeLaS3 cells by WST1 assay	[PMID: 15568771]
Hep 3B2	ED₅₀	0.6 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 16309328]
Hep 3B2	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 18606546]
Hep 3B2	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human Hep 3B cells by MTT microassay Cytotoxicity against human Hep 3B cells by MTT microassay	[PMID: 17320246]
Hep 3B2	IC₅₀	1.5 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
Hep 3B2	IC₅₀	10.53 μM Compound: 5-Fu	Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27993516]
Hep 3B2	IC₅₀	10.53 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay	[PMID: 26883148]
Hep 3B2	IC₅₀	10.53 μM Compound: 5FU	Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
Hep 3B2	IC₅₀	11.9 μM Compound: 5-FU	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 28371676]
Hep 3B2	IC₅₀	17.53 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay	[PMID: 27133593]
Hep 3B2	IC₅₀	2.66 μM Compound: 5-FU	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 28262527]
Hep 3B2	IC₅₀	22.99 μM Compound: 5-Fluorouracil	Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
Hep 3B2	IC₅₀	49.72 μM Compound: 5-FU	Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 28174107]
Hep 3B2	ED₅₀	7.15 x 10^-2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 11908984]
Hep 3B2	IC₅₀	7.2 x 10^-2 μg/mL Compound: 5-Fu	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 16038565]
Hep 3B2	IC₅₀	9.36 μM Compound: 5-Fluorouracil	Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay	[PMID: 27913179]
HEp-2	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human Hep2 cells after 72 hrs by MTT assay Antiproliferative activity against human Hep2 cells after 72 hrs by MTT assay	[PMID: 21524829]
HEp-2	IC₅₀	0.3 μM Compound: 5-fluorouracil	Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HEp-2	IC₅₀	128.7 μM Compound: 5-Fu	Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay	[PMID: 23792763]
HEp-2	IC₅₀	128.7 μM Compound: 5-FU	Antiproliferative activity against human Hep2 cells after 72 hrs by MTT method Antiproliferative activity against human Hep2 cells after 72 hrs by MTT method	[PMID: 17524655]
HEp-2	IC₅₀	2 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) Hep2 cells by SRB assay Cytotoxicity against Homo sapiens (human) Hep2 cells by SRB assay	10.1007/s00044-010-9500-5
HEp-2	IC₅₀	24.58 μM Compound: 5-Fu	Cytotoxicity against human Hep2 cells by MTT assay Cytotoxicity against human Hep2 cells by MTT assay	[PMID: 22801644]
HEp-2	IC₅₀	4.5 μM Compound: 5-FU	Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
HepG2	IC₅₀	> 10 μM Compound: 5-FU	Growth inhibition of human HepG2 cells after 72 hrs by MTS assay Growth inhibition of human HepG2 cells after 72 hrs by MTS assay	[PMID: 27704811]
HepG2	IC₅₀	> 100 μM Compound: 5-FU	Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 23313635]
HepG2	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human HepG2 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
HepG2	IC₅₀	> 150 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26320625]
HepG2	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
HepG2	IC₅₀	0.061 mM Compound: 5-Fluorouracil	Cytotoxicity in human HepG2 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human HepG2 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
HepG2	IC₅₀	0.07 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
HepG2	IC₅₀	0.52 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 32485532]
HepG2	IC₅₀	1.3 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 16499328]
HepG2	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method	[PMID: 23018096]
HepG2	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
HepG2	IC₅₀	1.4 μM Compound: 5-F	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 28254697]
HepG2	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
HepG2	IC₅₀	1.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 29798826]
HepG2	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
HepG2	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23800391]
HepG2	IC₅₀	10.17 μM Compound: 5FU	Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
HepG2	IC₅₀	10.3 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	10.1039/C6MD00169F
HepG2	IC₅₀	10.4 μM Compound: 5-Fu	Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
HepG2	IC₅₀	10.45 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 22801644]
HepG2	IC₅₀	10.53 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 28174107]
HepG2	IC₅₀	11.68 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
HepG2	IC₅₀	110.01 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 21962523]
HepG2	IC₅₀	112.1 μM Compound: 5-FU	Cytotoxicity in human HePG2 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human HePG2 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
HepG2	IC₅₀	12 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 6 days by MTT assay Cytotoxicity against human HepG2 cells after 6 days by MTT assay	[PMID: 29786436]
HepG2	IC₅₀	12.48 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay	[PMID: 24013415]
HepG2	IC₅₀	13.31 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28363444]
HepG2	IC₅₀	13.54 μM Compound: 2; 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27322756]
HepG2	IC₅₀	14.52 μM Compound: 2; 5-FU	Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
HepG2	IC₅₀	15.74 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay	[PMID: 29499490]
HepG2	IC₅₀	15.92 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22209486]
HepG2	IC₅₀	15.92 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 30359819]
HepG2	IC₅₀	16.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 26227777]
HepG2	IC₅₀	17.2 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28117202]
HepG2	IC₅₀	17.44 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
HepG2	IC₅₀	17.57 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
HepG2	IC₅₀	174.5 μM Compound: 5-Fuorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27017265]
HepG2	IC₅₀	18.35 μM Compound: 2; 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29202398]
HepG2	IC₅₀	18.85 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 after 48 hrs by MTT assay Cytotoxicity against human HepG2 after 48 hrs by MTT assay	[PMID: 21486698]
HepG2	IC₅₀	18.9 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
HepG2	IC₅₀	18.98 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 35609396]
HepG2	IC₅₀	18.98 μM Compound: 5-FU	Anticancer activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34425478]
HepG2	IC₅₀	19.2 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
HepG2	IC₅₀	19.45 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 24211021]
HepG2	IC₅₀	2.1 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 28262527]
HepG2	EC₅₀	2.21 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26883149]
HepG2	IC₅₀	2.24 μg/mL Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 29100732]
HepG2	IC₅₀	2.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
HepG2	IC₅₀	2.7 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 3 days by MTT assay Cytotoxicity against human HepG2 cells after 3 days by MTT assay	[PMID: 22000925]
HepG2	IC₅₀	2.78 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 21131104]
HepG2	IC₅₀	2.88 μM Compound: 5-FU	Antitumor activity against human HepG2 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human HepG2 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
HepG2	IC₅₀	2.98 μM Compound: 5-Fu	Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
HepG2	IC₅₀	20.1 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28400238]
HepG2	IC₅₀	20.4 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
HepG2	IC₅₀	205.19 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell growth after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell growth after 48 hrs by MTT assay	[PMID: 27422336]
HepG2	IC₅₀	21.9 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 23279864]
HepG2	IC₅₀	22.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23490159]
HepG2	EC₅₀	23.31 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 21889345]
HepG2	IC₅₀	23.6 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29486954]
HepG2	IC₅₀	237 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
HepG2	IC₅₀	24.96 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 23685571]
HepG2	IC₅₀	25 μg/mL Compound: 5FU	Cytotoxicity against human HepG2 cells after 48 hrs by SRB assay Cytotoxicity against human HepG2 cells after 48 hrs by SRB assay	[PMID: 21115211]
HepG2	IC₅₀	25.17 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27133593]
HepG2	IC₅₀	26.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24565905]
HepG2	IC₅₀	28.8 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28756264]
HepG2	IC₅₀	29.07 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 28458133]
HepG2	IC₅₀	29.1 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 28494251]
HepG2	IC₅₀	29.81 μM Compound: 5-Fu	Antitumor activity human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36216031]
HepG2	IC₅₀	29.87 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 23202484]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 3 days by MTT assay Cytotoxicity against human HepG2 cells after 3 days by MTT assay	[PMID: 24095745]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 25151580]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24378217]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23988357]
HepG2	ED₅₀	3.3 x 10^-2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 11908984]
HepG2	IC₅₀	3.6 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
HepG2	IC₅₀	30.48 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
HepG2	IC₅₀	30.79 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
HepG2	IC₅₀	30.8 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30527868]
HepG2	IC₅₀	31.7 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30739827]
HepG2	IC₅₀	31.98 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 2 days by MTT assay Cytotoxicity against human HepG2 cells after 2 days by MTT assay	[PMID: 25841196]
HepG2	IC₅₀	31.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30108826]
HepG2	IC₅₀	31.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30092368]
HepG2	IC₅₀	32.22 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22687745]
HepG2	IC₅₀	32.57 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
HepG2	IC₅₀	32.57 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
HepG2	IC₅₀	32.6 μM Compound: 5-Fu	Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27993516]
HepG2	IC₅₀	32.6 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 28371676]
HepG2	IC₅₀	32.87 μM Compound: 5-FU	Growth inhibition of human HepG2 cells after 24 hrs by MTT assay Growth inhibition of human HepG2 cells after 24 hrs by MTT assay	[PMID: 28011220]
HepG2	IC₅₀	33.68 μM Compound: 5-fluorouracil	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay	[PMID: 31945642]
HepG2	IC₅₀	34 μM Compound: 5-fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22304344]
HepG2	IC₅₀	35.99 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 26546214]
HepG2	IC₅₀	36.1 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay	[PMID: 36288556]
HepG2	IC₅₀	36.6 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29305189]
HepG2	IC₅₀	36.62 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30007564]
HepG2	IC₅₀	36.74 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
HepG2	IC₅₀	38.34 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24953029]
HepG2	IC₅₀	39.74 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
HepG2	IC₅₀	4.35 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24119869]
HepG2	IC₅₀	4.8 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22727445]
HepG2	IC₅₀	40.18 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
HepG2	IC₅₀	40.34 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
HepG2	IC₅₀	40.34 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
HepG2	IC₅₀	40.34 μM Compound: 5-Fu	Growth inhibition against human HepG2 cells after 48 hrs by MTT assay Growth inhibition against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23999046]
HepG2	IC₅₀	40.34 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23558238]
HepG2	IC₅₀	41.62 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
HepG2	IC₅₀	46.31 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22483608]
HepG2	IC₅₀	46.83 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay	[PMID: 27287368]
HepG2	IC₅₀	46.83 μM Compound: Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27128180]
HepG2	IC₅₀	46.83 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26363869]
HepG2	IC₅₀	46.83 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 25016234]
HepG2	IC₅₀	46.83 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22809558]
HepG2	IC₅₀	47.97 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30142612]
HepG2	IC₅₀	49.02 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28110871]
HepG2	IC₅₀	49.02 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HepG2	IC₅₀	49.72 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26883148]
HepG2	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 27987485]
HepG2	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 29326016]
HepG2	IC₅₀	5 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 22409771]
HepG2	IC₅₀	5.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
HepG2	IC₅₀	5.7 μM Compound: 5FU	Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HepG2	IC₅₀	5.82 μM Compound: 5-FU	Antiproliferative activity in human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity in human HepG2 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
HepG2	IC₅₀	5.86 μM Compound: 5-Fluorouracil	Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
HepG2	IC₅₀	51.5 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23067549]
HepG2	EC₅₀	52.43 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 20409617]
HepG2	IC₅₀	55.2 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
HepG2	IC₅₀	55.74 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
HepG2	IC₅₀	56.2 μM Compound: 5-Fluoruracil	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22555152]
HepG2	IC₅₀	59.12 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29958763]
HepG2	IC₅₀	6.6 μM Compound: FUra	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 27073055]
HepG2	IC₅₀	6.6 μM Compound: FUra	Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
HepG2	IC₅₀	6.69 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
HepG2	IC₅₀	6.9 μM Compound: 5-Fluorouracil	Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
HepG2	IC₅₀	60.73 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 31401008]
HepG2	IC₅₀	63.37 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30108924]
HepG2	IC₅₀	66.42 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 30826506]
HepG2	IC₅₀	66.42 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 33831559]
HepG2	IC₅₀	68 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 31057737]
HepG2	GI₅₀	7 μM Compound: 5-FU	Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 27688184]
HepG2	IC₅₀	7.22 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 31546197]
HepG2	IC₅₀	7.43 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24286761]
HepG2	IC₅₀	7.6 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24547794]
HepG2	IC₅₀	72.33 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay	[PMID: 34838335]
HepG2	IC₅₀	76.7 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 2 days by alamar blue assay Cytotoxicity against human HepG2 cells after 2 days by alamar blue assay	[PMID: 22093761]
HepG2	IC₅₀	76.9 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability by MTT assay Cytotoxicity against human HepG2 cells assessed as decrease in cell viability by MTT assay	[PMID: 29489361]
HepG2	IC₅₀	8 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27343853]
HepG2	IC₅₀	8 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 25969171]
HepG2	IC₅₀	8.02 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay	[PMID: 31884408]
HepG2	IC₅₀	8.2 ng/mL Compound: fluorouracil	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 22011319]
HepG2	IC₅₀	8.6 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 22204901]
HepG2	IC₅₀	8.6 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
HepG2	IC₅₀	8.6 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against human HepG2 cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
HepG2	IC₅₀	8.66 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
HepG2	IC₅₀	8.69 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 32791397]
HepG2	IC₅₀	8.8 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31276896]
HepG2	IC₅₀	8.9 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
HepG2	IC₅₀	8.9 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 28525845]
HepG2	IC₅₀	8.9 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 27875779]
HepG2	IC₅₀	86.87 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition by MTT assay	[PMID: 24684840]
HepG2	IC₅₀	9.1 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 23022735]
HepG2	IC₅₀	9.2 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 3 days by MTT assay Antiproliferative activity against human HepG2 cells after 3 days by MTT assay	[PMID: 18424155]
HepG2	IC₅₀	9.23 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
HepG2	IC₅₀	9.3 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22647218]
HGC-27	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
HGC-27	IC₅₀	11.02 μM Compound: 5-FU	Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay	[PMID: 28759876]
HGC-27	IC₅₀	14.72 μM Compound: 5-FU	Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay	[PMID: 28431881]
HGC-27	IC₅₀	18 μM Compound: 5-FU	Cytotoxicity against human HGC27 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human HGC27 cells assessed as reduction in cell viability by MTT assay	[PMID: 31029946]
HGC-27	IC₅₀	27.5 μM Compound: 5-Fu	Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
HGC-27	IC₅₀	4.28 μM Compound: 5-FU	Anticancer activity against human HGC-27 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human HGC-27 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
HGC-27	IC₅₀	45.2 μM Compound: 5-FU	Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 35286954]
HGC-27	IC₅₀	5.75 μM Compound: 5-Fu	Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
HGC-27	IC₅₀	76.62 μM Compound: 5-FU	Cytotoxicity in human HGC-27 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HGC-27 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HGC-27	IC₅₀	8.22 μM Compound: 5-FU	Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay	[PMID: 30108876]
HGC-27	IC₅₀	8.22 μM Compound: 5-Fu	Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay	[PMID: 28456031]
HL-60	IC₅₀	> 30 μM Compound: 5-FU	Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 29133061]
HL-60	IC₅₀	0.06 μM Compound: 5-FU	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 22959518]
HL-60	CC₅₀	0.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human HL60 cells after 5 days by MTT assay Cytotoxicity against human HL60 cells after 5 days by MTT assay	[PMID: 20227144]
HL-60	IC₅₀	0.16 μM Compound: fluorouracil	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 17291040]
HL-60	IC₅₀	1.62 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay	[PMID: 28152430]
HL-60	IC₅₀	10.05 μM Compound: 5-Fu	Growth inhibition against human HL60 cells after 48 hrs by MTT assay Growth inhibition against human HL60 cells after 48 hrs by MTT assay	[PMID: 23999046]
HL-60	IC₅₀	10.05 μM Compound: 5-Fu	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 23558238]
HL-60	IC₅₀	10.45 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 25529742]
HL-60	IC₅₀	2.37 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 29524728]
HL-60	IC₅₀	2.37 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 29407983]
HL-60	IC₅₀	2.45 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
HL-60	IC₅₀	2.7 pM Compound: 5-FU	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 21640594]
HL-60	IC₅₀	2.8 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method	[PMID: 29131616]
HL-60	IC₅₀	21.38 μM Compound: 5-FU	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 18644718]
HL-60	IC₅₀	22.3 μM Compound: 5-FU	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 23867385]
HL-60	IC₅₀	22.54 μM Compound: FUra	Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 25644674]
HL-60	IC₅₀	25.4 μg/mL Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HL60 cells by MTT assay Cytotoxicity against Homo sapiens (human) HL60 cells by MTT assay	10.1007/s00044-009-9193-9
HL-60	IC₅₀	266 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HL60 cells after 96 hr by MTT assay Cytotoxicity against Homo sapiens (human) HL60 cells after 96 hr by MTT assay	10.1007/s00044-011-9778-y
HL-60	IC₅₀	266 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay	[PMID: 22424614]
HL-60	IC₅₀	27.01 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay	[PMID: 25164762]
HL-60	IC₅₀	27.43 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HL-60	IC₅₀	3.46 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 29635169]
HL-60	IC₅₀	3.69 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
HL-60	GI₅₀	3.8 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining	[PMID: 18491866]
HL-60	IC₅₀	42.8 μM Compound: 5-FU	Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay	[PMID: 31253531]
HL-60	IC₅₀	5.4 μM Compound: 5-FU	Anticancer activity against Homo sapiens (human) HL60 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay Anticancer activity against Homo sapiens (human) HL60 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay	10.1007/s00044-012-0240-6
HL-60	IC₅₀	54.54 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay	[PMID: 29958763]
HL-60	IC₅₀	65.3 μM Compound: 5-FU	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 19324555]
HL-60	IC₅₀	65.3 μM Compound: 5-FU	In vitro inhibitory concentration required against human leukemic HL-60 cell line was determined after 48 hrs of drug exposure using MTT method In vitro inhibitory concentration required against human leukemic HL-60 cell line was determined after 48 hrs of drug exposure using MTT method	[PMID: 15380199]
HL-60	IC₅₀	67.2 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay	[PMID: 29305189]
HL-60	IC₅₀	68.3 μM Compound: 5-Fu	Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay	[PMID: 22244588]
HL-60	IC₅₀	81.13 μM Compound: 5-FU	Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HL-60	IC₅₀	9.1 μM Compound: 5-fluorouracil	Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
HL-60	IC₅₀	9.5 μM Compound: 5-fluorouracil	Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
HL-60(TB)	GI₅₀	100 nM Compound: 5FU	Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay	[PMID: 23094992]
HL-60(TB)	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay	[PMID: 22512908]
HL-60(TB)	GI₅₀	2.3 μM Compound: 5-FU	Anticancer activity against human HL-60(TB) cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HL-60(TB) cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HL-60(TB)	GI₅₀	2.3 μM Compound: 5-FU	Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HL-60(TB)	IC₅₀	85.1 μM Compound: 5-Fluorouracil	Antileukemic activity against human HL-60(TB) cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human HL-60(TB) cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
HOP-62	GI₅₀	0.39 μM Compound: 5-FU	Anticancer activity against human HOP-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HOP-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HOP-62	GI₅₀	0.39 μM Compound: 5-FU	Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HOP-62	GI₅₀	4.1 μM Compound: 5FU	Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
HOP-92	GI₅₀	77.9 μM Compound: 5-FU	Anticancer activity against human HOP-92 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HOP-92 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HOP-92	GI₅₀	77.9 μM Compound: 5-FU	Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
Hs-578T	GI₅₀	9.77 μM Compound: 5-FU	Anticancer activity against human Hs-578T cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human Hs-578T cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
Hs-578T	GI₅₀	9.77 μM Compound: 5-FU	Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HSC-2	CC₅₀	> 1000 μM Compound: 5-FU	Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay	[PMID: 33744685]
HSC-2	CC₅₀	13 μM Compound: 5-FU	Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32795767]
HSC-2	CC₅₀	47 μM Compound: 5-FU	Cytotoxicity against human HSC2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31532650]
HSC-3	CC₅₀	13 μM Compound: 5-FU	Cytotoxicity against human HSC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32795767]
HSC-4	CC₅₀	25 μM Compound: 5-FU	Cytotoxicity against human HSC4 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC4 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31532650]
HT-1080	EC₅₀	0.29 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 12444707]
HT-1080	ED₅₀	0.48 μg/mL Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells after 4 days by MTT assay Antiproliferative activity against human HT1080 cells after 4 days by MTT assay	[PMID: 11374950]
HT-1080	EC₅₀	1.38 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 12027739]
HT-1080	IC₅₀	1.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 11575942]
HT-1080	IC₅₀	15.2 μM Compound: 5-FU	Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay	[PMID: 23067549]
HT-1080	IC₅₀	3.06 μM Compound: 5-Fu	Cytotoxicity against human HT1080 cells by MTT assay Cytotoxicity against human HT1080 cells by MTT assay	[PMID: 22801644]
HT-1080	IC₅₀	35.62 μM Compound: 5-Fu	Growth inhibition against human HT1080 cells after 48 hrs by MTT assay Growth inhibition against human HT1080 cells after 48 hrs by MTT assay	[PMID: 23999046]
HT-1080	IC₅₀	35.62 μM Compound: 5-Fu	Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay	[PMID: 23558238]
HT-1080	IC₅₀	3700 nM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 14640513]
HT-1080	IC₅₀	5.2 μM Compound: 5-fluorouracil	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 19919052]
HT-1080	IC₅₀	70.8 μM Compound: 5-Fu	Cytotoxicity against human HT1080 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human HT1080 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 23647462]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Cytotoxicity against human HT1080 cells by MTT assay Cytotoxicity against human HT1080 cells by MTT assay	[PMID: 11430002]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 11325233]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 11277741]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Cytotoxicity against human HT1080 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide assay Cytotoxicity against human HT1080 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide assay	[PMID: 11141109]
HT-1080	IC₅₀	8.58 μM Compound: 5-Fluoro uracil	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 19689125]
HT-1080	IC₅₀	9.45 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 18440233]
HT-22	CC₅₀	8.1 μM Compound: 5-Fu	Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32832031]
HT-29	IC₅₀	> 10 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
HT-29	IC₅₀	> 100 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
HT-29	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HT-29	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HT-29	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 24 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 24 hrs by MTT assay	[PMID: 26922233]
HT-29	GI₅₀	0.17 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HT-29	GI₅₀	0.17 μM Compound: 5-FU	Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HT-29	ED₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 16309328]
HT-29	GI₅₀	0.4 μg/mL Compound: 5FU	Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
HT-29	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human HT29 cells by MTT assay Cytotoxicity against human HT29 cells by MTT assay	[PMID: 18606546]
HT-29	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human HT29 cells by MTT microassay Cytotoxicity against human HT29 cells by MTT microassay	[PMID: 17320246]
HT-29	IC₅₀	1.08 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
HT-29	IC₅₀	10.26 μg/mL Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HT-29 cells by MTT assay Cytotoxicity against Homo sapiens (human) HT-29 cells by MTT assay	10.1007/s00044-009-9193-9
HT-29	IC₅₀	12.2 μM Compound: 5-FU	Antitumor activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
HT-29	GI₅₀	12.6 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay	[PMID: 32832031]
HT-29	IC₅₀	12.67 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay	[PMID: 32992255]
HT-29	IC₅₀	13.37 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
HT-29	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HT-29	IC₅₀	14.9 μM Compound: 1; 5-FU	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 33819035]
HT-29	IC₅₀	146.2 μM Compound: 5-FU	Cytotoxicity in human HT-29 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human HT-29 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
HT-29	IC₅₀	15.83 μM Compound: 5-fluorouracil	Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay	[PMID: 26413725]
HT-29	IC₅₀	15.96 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
HT-29	IC₅₀	16.07 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
HT-29	IC₅₀	17.2 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 2 days by MTT assay Cytotoxicity against human HT-29 cells after 2 days by MTT assay	[PMID: 24767839]
HT-29	IC₅₀	17.48 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
HT-29	IC₅₀	18.77 nM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36269639]
HT-29	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
HT-29	IC₅₀	2.58 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 3 days by SRB assay Cytotoxicity against human HT-29 cells after 3 days by SRB assay	[PMID: 24704691]
HT-29	IC₅₀	2.8 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 27092413]
HT-29	IC₅₀	22.23 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 29958763]
HT-29	IC₅₀	23.9 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
HT-29	IC₅₀	24.5 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay	[PMID: 26703795]
HT-29	IC₅₀	24.5 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 23665106]
HT-29	IC₅₀	24.87 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay	[PMID: 24583355]
HT-29	IC₅₀	25 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26922233]
HT-29	IC₅₀	25.08 μM Compound: FUra	Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
HT-29	IC₅₀	25.9 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT-29 cells cultured as 3D spheroids assessed as inhibition of spheroid formation measured after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells cultured as 3D spheroids assessed as inhibition of spheroid formation measured after 48 hrs by MTT assay	[PMID: 33872002]
HT-29	IC₅₀	3.24 μM Compound: 5-Fluorouracil	Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as inhibition of cell growth after 48 hr by MTT assay Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as inhibition of cell growth after 48 hr by MTT assay	10.1007/s00044-012-0209-5
HT-29	IC₅₀	4.6 μM Compound: 5-Fluorouracil	Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
HT-29	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 28494251]
HT-29	IC₅₀	5.2 μM Compound: 1; 5-FU	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay	[PMID: 33819035]
HT-29	IC₅₀	5.3 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
HT-29	IC₅₀	5.31 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 36923920]
HT-29	IC₅₀	540 μM Compound: 5-FU	Cytotoxicity against HT29 cells after 48 hrs by MTT assay Cytotoxicity against HT29 cells after 48 hrs by MTT assay	[PMID: 17604394]
HT-29	IC₅₀	6.3 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 26922233]
HT-29	IC₅₀	6.35 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 23644215]
HT-29	IC₅₀	6.5 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30368201]
HT-29	IC₅₀	690 nM Compound: Fluorouracil	Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay	[PMID: 2778449]
HT-29	IC₅₀	7.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining	[PMID: 22959205]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method	[PMID: 22450132]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method	[PMID: 22765897]
HT-29	ED₅₀	7.4 x 10^-2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 11908984]
HT-29	ED₅₀	7.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT-29 cells by Alamar blue assay Cytotoxicity against human HT-29 cells by Alamar blue assay	[PMID: 24128077]
HT-29	IC₅₀	8.3 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 29133061]
HT-29	GI₅₀	8.9 μM Compound: 5FU	Cytotoxicity against human HT29 cells after 48 hrs Cytotoxicity against human HT29 cells after 48 hrs	[PMID: 18798609]
HT-29	IC₅₀	9.72 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) HT-29 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) HT-29 cells after 72 hr by MTT assay	10.1007/s00044-011-9549-9
HT-29	IC₅₀	9.99 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
hTERT-BJ	IC₅₀	5.5 μM Compound: 5-Fluorouracil	Cytotoxicity activity against human hTERT-BJ cells by MTT assay Cytotoxicity activity against human hTERT-BJ cells by MTT assay	[PMID: 31546197]
hTERT-BJ	GI₅₀	5.5 μM Compound: 5-FU	Cytotoxicity against human hTERT-BJ cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human hTERT-BJ cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
hTERT-BJ	GI₅₀	5.5 μM Compound: 5-FU	Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay	[PMID: 28728108]
Huh-7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26320625]
Huh-7	IC₅₀	1.06 μM Compound: 5-FU	Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
Huh-7	IC₅₀	10.41 μg/mL Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 26546214]
Huh-7	IC₅₀	15.85 μM Compound: 5-Fu	Growth inhibition of human HuH7 cells after 48 hrs by MTT assay Growth inhibition of human HuH7 cells after 48 hrs by MTT assay	[PMID: 23353737]
Huh-7	IC₅₀	2.98 mM Compound: 5-FU	Antiproliferative activity against human HuH7 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Antiproliferative activity against human HuH7 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 28073674]
Huh-7	IC₅₀	20.03 μg/mL Compound: 5-F	Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay	[PMID: 24342667]
Huh-7	IC₅₀	21 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 30108969]
Huh-7	IC₅₀	21 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
Huh-7	IC₅₀	30 μM Compound: 5-FU	Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 29326016]
Huh-7	IC₅₀	30.3 μM Compound: 5-Fu	Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay	[PMID: 36288556]
Huh-7	IC₅₀	30.7 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 25462277]
Huh-7	IC₅₀	30.7 μM Compound: 5FU	Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
Huh-7	IC₅₀	30.7 μM Compound: 5-Fu	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 22409771]
Huh-7	IC₅₀	30.7 μM Compound: 5FU	Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay	10.1039/C4MD00306C
Huh-7	IC₅₀	390 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as reduction in cell growth after 48 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as reduction in cell growth after 48 hrs by MTT assay	[PMID: 27422336]
Huh-7	IC₅₀	5.63 μM Compound: 5-FU	Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay	[PMID: 29316536]
HuTu80	GI₅₀	0.4 μg/mL Compound: 5FU	Cytotoxicity against human HuTu 80 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human HuTu 80 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
HuTu80	IC₅₀	65.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human HuTu80 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human HuTu80 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
HUVEC	IC₅₀	> 200 μM Compound: 5-FLU	Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 34606997]
HUVEC	IC₅₀	24.12 μM Compound: 5-Fu	Cytotoxicity against HUVEC after 48 hrs by MTT assay Cytotoxicity against HUVEC after 48 hrs by MTT assay	[PMID: 24953029]
HUVEC	GI₅₀	3.6 nM Compound: 5FU	Growth inhibition of human HUVEC cells after 48 hrs by SRB assay Growth inhibition of human HUVEC cells after 48 hrs by SRB assay	[PMID: 23094992]
HUVEC	IC₅₀	56 μM Compound: 5-FU	Cytotoxicity in HUVEC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in HUVEC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 28754470]
HUVEC	IC₅₀	56 μM Compound: 5-FU	Cytotoxicity against human HUVEC cells after 48 hrs by MTT assay Cytotoxicity against human HUVEC cells after 48 hrs by MTT assay	[PMID: 25151580]
HUVEC	IC₅₀	56 μM Compound: 5-FU	Cytotoxicity against human HUVEC after 48 hrs by MTT assay Cytotoxicity against human HUVEC after 48 hrs by MTT assay	[PMID: 24378217]
HUVEC	IC₅₀	56.37 μM Compound: 5-Fu	Cytotoxicity against human HUVEC cells after 2 days by MTT assay Cytotoxicity against human HUVEC cells after 2 days by MTT assay	[PMID: 25841196]
HUVEC	IC₅₀	79.6 μM Compound: 5-Fluorouracil	Cytotoxicity against HUVEC assessed as cell growth inhibition by MTT assay Cytotoxicity against HUVEC assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
HUVEC	GI₅₀	9.72 μM Compound: 5-Fu	Growth inhibition of HUVEC cells after 48 hrs by SRB assay Growth inhibition of HUVEC cells after 48 hrs by SRB assay	[PMID: 22512908]
HUVEC	IC₅₀	96 μM Compound: 5-FLU	Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 34606997]
IEC-6	IC₅₀	0.66 μM Compound: 5-FU	Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
IGROV-1	GI₅₀	1.22 μM Compound: 5-FU	Anticancer activity against human IGROV-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human IGROV-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
IGROV-1	GI₅₀	1.22 μM Compound: 5-FU	Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
IGROV-1	IC₅₀	10.6 μM Compound: 5FU	Cytotoxicity against human IGROV1 cells after 72 hrs Cytotoxicity against human IGROV1 cells after 72 hrs	[PMID: 30035541]
IGROV-1	GI₅₀	8.12 nM Compound: 5FU	Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay	[PMID: 23094992]
IGROV-1	GI₅₀	9.1 μM Compound: 5-Fu	Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay	[PMID: 22512908]
IMR-32	IC₅₀	1.3 μM Compound: 5-FU	Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay	[PMID: 25176329]
IMR-32	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay	[PMID: 24056146]
IMR-32	IC₅₀	18 μM Compound: 5-fluorouracil	Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
IMR-32	IC₅₀	5.7 μM Compound: 5-fluorouracil	Cytotoxicity against human IMR32 cells after 48 hrs by CellTiter-Glo assay Cytotoxicity against human IMR32 cells after 48 hrs by CellTiter-Glo assay	[PMID: 31999116]
IMR-90	IC₅₀	136.4 μM Compound: 5-Fluorouracil	Cytotoxicity against human IMR90 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human IMR90 cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
Jurkat	IC₅₀	87 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
Jurkat	IC₅₀	87.73 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay	[PMID: 18469809]
K562	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
K562	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 19324555]
K562	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human K562 cells after 72 hrs Antiproliferative activity against p53 deficient human K562 cells after 72 hrs	[PMID: 18469809]
K562	GI₅₀	0.9 μg/mL Compound: 5FU	Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
K562	IC₅₀	114.5 μM Compound: 5-Fu	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 23356786]
K562	IC₅₀	12.21 μM Compound: 5-FU	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 30677614]
K562	IC₅₀	126 μM Compound: 5-Fluorouracil	Antileukemic activity against human K562 cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human K562 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
K562	ED₅₀	16.22 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells after 6 hrs by Alamar Blue assay Cytotoxicity against human K562 cells after 6 hrs by Alamar Blue assay	[PMID: 24020806]
K562	GI₅₀	16.7 μM Compound: 5FU	Cytotoxicity against human K562 cells after 48 hrs Cytotoxicity against human K562 cells after 48 hrs	[PMID: 18798609]
K562	GI₅₀	18.5 μM Compound: 5-FU	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 29040954]
K562	GI₅₀	19 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 28763647]
K562	IC₅₀	2.1 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 22537362]
K562	IC₅₀	20.21 μM Compound: 5-FU	Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
K562	IC₅₀	20.7 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 30737134]
K562	ED₅₀	21 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells by Alamar blue assay Cytotoxicity against human K562 cells by Alamar blue assay	[PMID: 24128077]
K562	IC₅₀	23.55 μM Compound: 5-Fu	Growth inhibition against human K562 cells after 48 hrs by MTT assay Growth inhibition against human K562 cells after 48 hrs by MTT assay	[PMID: 23999046]
K562	IC₅₀	23.55 μM Compound: 5-Fu	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 23558238]
K562	IC₅₀	28 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 23535322]
K562	IC₅₀	3.54 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells after 72 hrs by MTT assay Antiproliferative activity against human K562 cells after 72 hrs by MTT assay	[PMID: 28165738]
K562	GI₅₀	3.58 μM Compound: 5-FU	Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
K562	GI₅₀	3.58 μM Compound: 5-FU	Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
K562	IC₅₀	3.86 μM Compound: 5-FU	Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
K562	IC₅₀	3.94 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
K562	IC₅₀	3.94 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
K562	IC₅₀	30.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
K562	IC₅₀	31.6 μM Compound: 5-Fu	Anticancer activity against human K562 cells after 48 hrs by MTT assay Anticancer activity against human K562 cells after 48 hrs by MTT assay	[PMID: 25462264]
K562	IC₅₀	32.92 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells by disk diffusion soft agar colony formation assay Cytotoxicity against human K562 cells by disk diffusion soft agar colony formation assay	[PMID: 31117520]
K562	IC₅₀	38 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 21131104]
K562	IC₅₀	38.58 μM Compound: 5-FU	Growth inhibition of human K562 cells after 48 hrs by WST1 assay Growth inhibition of human K562 cells after 48 hrs by WST1 assay	[PMID: 28126436]
K562	IC₅₀	38.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human K562 cells by MTT reduction assay Antiproliferative activity against human K562 cells by MTT reduction assay	[PMID: 33421712]
K562	IC₅₀	4.02 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
K562	IC₅₀	41.66 μM Compound: 5-FU	Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
K562	IC₅₀	45.4 μM Compound: 5-FU	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 20494492]
K562	IC₅₀	45.4 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) K562 cells by MTT assay Cytotoxicity against Homo sapiens (human) K562 cells by MTT assay	10.1007/s00044-010-9395-1
K562	IC₅₀	8.48 μg/mL Compound: 5-FU	Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 30114660]
K562	IC₅₀	9.49 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
K562/Adr	IC₅₀	31.9 μM Compound: 5-FU	Cytotoxicity against human K562/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human K562/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
KATO III stomach cancer cell line	EC₅₀	21.4 μM Compound: 5FU	Cytotoxicity against human KATO III stomach cancer cell line assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human KATO III stomach cancer cell line assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
KB	IC₅₀	> 10 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 2 to 7 days by neutral red assay Cytotoxicity against human KB cells after 2 to 7 days by neutral red assay	[PMID: 11374943]
KB	IC₅₀	1.23 μM Compound: 5-Fu	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 24953029]
KB	ED₅₀	1.25 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 3 days by trypan blue exclusion technique Cytotoxicity against human KB cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
KB	IC₅₀	11.9 μM Compound: 5-FU	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 21144621]
KB	IC₅₀	12.5 μM Compound: Fluorouracil	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 21843939]
KB	IC₅₀	12.5 μM Compound: fluorouracil	Cytotoxicity against human KB cells after 72 hrs MTT assay Cytotoxicity against human KB cells after 72 hrs MTT assay	[PMID: 19846302]
KB	IC₅₀	13.4 μM Compound: 5-fu	Cytotoxicity against human KB cells after 48 hrs Cytotoxicity against human KB cells after 48 hrs	[PMID: 17000031]
KB	IC₅₀	15.9 μM Compound: Flurouracil	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 21273072]
KB	IC₅₀	2.16 μM Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 21131104]
KB	IC₅₀	4.46 nM Compound: Fluorouracil	Cytotoxicity against human KB cells by MTT assay Cytotoxicity against human KB cells by MTT assay	[PMID: 19345581]
KB	IC₅₀	4.46 μM Compound: Fluorouracil	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 20356655]
KB	IC₅₀	4.84 μM Compound: FUra	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 27073055]
KB	IC₅₀	4.84 μM Compound: FUra	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 23867603]
KB	IC₅₀	4.84 μM Compound: FUra	Cytotoxicity against human KB cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human KB cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
KB	GI₅₀	5.2 μM Compound: 5FU	Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
KB	IC₅₀	53.52 μM Compound: 5-FU	Antiproliferative activity against human KB cells after 48 hrs by MTT assay Antiproliferative activity against human KB cells after 48 hrs by MTT assay	[PMID: 25164762]
KB	IC₅₀	6.8 μM Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 22537362]
KB	IC₅₀	7.7 pM Compound: 5-FU	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 21640594]
KB	IC₅₀	8.1 μM Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 4 days by MTT assay Cytotoxicity against human KB cells after 4 days by MTT assay	[PMID: 24359303]
KB	IC₅₀	8.28 μM Compound: 5-FU	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 22749192]
KB	IC₅₀	9 μM Compound: Fluorouracil	Cytotoxicity against human KB cells after 72 hrs ny MTT assay Cytotoxicity against human KB cells after 72 hrs ny MTT assay	[PMID: 22200404]
KB	IC₅₀	9.85 μM Compound: 5-FU	Antiproliferative activity against human KB cells after 72 hrs by MTT assay Antiproliferative activity against human KB cells after 72 hrs by MTT assay	[PMID: 22079378]
KCL-22	IC₅₀	3.52 μM Compound: FU	Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay	[PMID: 24941129]
KG-1	IC₅₀	82.97 μM Compound: 2; 5-FU	Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay	[PMID: 27322756]
KM12	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
KM12	GI₅₀	0.21 μM Compound: 5-FU	Anticancer activity against human KM12 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human KM12 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
KM12	GI₅₀	0.21 μM Compound: 5-FU	Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
KM12	IC₅₀	12.26 μM Compound: 5-FU	Anticancer activity against human KM12 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Anticancer activity against human KM12 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34438126]
KM12	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
KM12	IC₅₀	7.94 μM Compound: 5-Fluorouracil	Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
L02	IC₅₀	> 10 μM Compound: 5-Fu	Cytotoxicity against human LO2 cells after 48 hrs by MTT assay Cytotoxicity against human LO2 cells after 48 hrs by MTT assay	[PMID: 26714048]
L02	IC₅₀	> 200 μM Compound: 5-FU	Cytotoxicity against human LO2 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human LO2 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
L02	IC₅₀	> 40 μM Compound: 5-Fu	Antiproliferative activity against human L02 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human L02 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
L02	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 31877536]
L02	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human L02 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human L02 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
L02	IC₅₀	10.6 μM Compound: Fluorouracil	Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
L02	IC₅₀	12.85 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
L02	IC₅₀	14.53 μg/mL Compound: 5-Fu	Cytotoxicity against human HL7702 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HL7702 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
L02	IC₅₀	19.1 μM Compound: 5-FU	Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay	[PMID: 28947149]
L02	IC₅₀	19.12 μM Compound: 5-Fu	Cytotoxicity in human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
L02	IC₅₀	25.9 μM Compound: 5-FU	Cytotoxicity against human L02 measured after 72 hrs by MTT assay Cytotoxicity against human L02 measured after 72 hrs by MTT assay	[PMID: 27537924]
L02	IC₅₀	25.9 μM Compound: 5-FU	Cytotoxicity against human L02 cells after 72 hrs by MTT assay Cytotoxicity against human L02 cells after 72 hrs by MTT assay	[PMID: 26595184]
L02	IC₅₀	29.53 μM Compound: 5-Fu	Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
L02	IC₅₀	32.546 μM Compound: 5-FU	Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay	[PMID: 28301815]
L02	IC₅₀	44.05 μM Compound: 5-FU	Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
L02	IC₅₀	46 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay	[PMID: 28756264]
L02	IC₅₀	46.57 μM Compound: 5-Fu	Growth inhibition of human L02 cells after 48 hrs by MTT assay Growth inhibition of human L02 cells after 48 hrs by MTT assay	[PMID: 23353737]
L02	IC₅₀	46.57 μM Compound: 5-Fu	Cytotoxicity against human L02 cells by after 48 hrs by MTT assay Cytotoxicity against human L02 cells by after 48 hrs by MTT assay	[PMID: 22579780]
L02	IC₅₀	56 μM Compound: 5-fluorouracil	Cytotoxicity against human L02 cells after 48 hrs by MTT assay Cytotoxicity against human L02 cells after 48 hrs by MTT assay	[PMID: 21131104]
L02	IC₅₀	58.74 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay	[PMID: 30108826]
L02	IC₅₀	58.74 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay	[PMID: 30092368]
L02	IC₅₀	58.74 μM Compound: 5-FU	Cytotoxicity against human HL7702 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HL7702 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
L02	IC₅₀	95.36 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells assessed as growth inhibition by MTT assay Cytotoxicity against human HL-7702 cells assessed as growth inhibition by MTT assay	[PMID: 24684840]
L1210	IC₅₀	> 500 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	> 500 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	≥ 10 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15 mins by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15 mins by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.02 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.06 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.22 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.32 μM Compound: 1, 5-FU	Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting	[PMID: 21892829]
L1210	IC₅₀	0.33 μM Compound: 5-Fluorouracil	Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method	[PMID: 27750154]
L1210	IC₅₀	0.33 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting	[PMID: 25435471]
L1210	IC₅₀	0.33 μM Compound: 5-Fluorouracil	Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method	[PMID: 24906510]
L1210	IC₅₀	0.33 μM Compound: 5FU	Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay	[PMID: 24631358]
L1210	IC₅₀	0.37 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.49 μM Compound: 5-Fluorouracil	Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis	[PMID: 22405290]
L1210	IC₅₀	0.56 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis	[PMID: 21330014]
L1210	IC₅₀	0.56 μM Compound: 5-FU	Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis	[PMID: 21232828]
L1210	IC₅₀	0.6 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.69 μM Compound: 5-FU	Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay	[PMID: 18424155]
L1210	IC₅₀	0.97 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	1.1 pM Compound: 5-FU	Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay	[PMID: 21640594]
L1210	ED₅₀	1.41 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse L1210 cells after 3 days by trypan blue exclusion technique Cytotoxicity against mouse L1210 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
L1210	IC₅₀	1010 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 8 h treatment Growth inhibition in L1210 mouse leukemia cells after 8 h treatment	[PMID: 11728193]
L1210	IC₅₀	200 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment	[PMID: 11728193]
L1210	IC₅₀	2500 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment	[PMID: 11728193]
L1210	IC₅₀	360 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 24 h treatment Growth inhibition in L1210 mouse leukemia cells after 24 h treatment	[PMID: 11728193]
L1210	IC₅₀	4.9 μM Compound: 5-FU	Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	51 μM Compound: 5-FU	Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA by liquid scintillation counting Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	7 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting	[PMID: 21330014]
L1210/C	IC₅₀	0.2 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against mouse leukemia cell line L1210/c after 72 hr of incubation The compound was evaluated for antitumoral activity against mouse leukemia cell line L1210/c after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
L929	IC₅₀	> 100 μM Compound: 5-Fu	Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation by MTT assay Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
L929	IC₅₀	1.38 μM Compound: 5-Fu	Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay	[PMID: 22687745]
L929	IC₅₀	2.98 μM Compound: 5-Fu	Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay	[PMID: 26786698]
Leukemia cell	GI₅₀	1.51 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by SRB assay Cytotoxicity against human leukemia cells after 48 hrs by SRB assay	[PMID: 23994328]
Leukemia cell	GI₅₀	15.09 μM Compound: 5-FU	Growth inhibition of human leukemia cells after 48 hrs Growth inhibition of human leukemia cells after 48 hrs	[PMID: 18950904]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Growth inhibition of human leukemia cells after 48 hrs by coulter counter method Growth inhibition of human leukemia cells after 48 hrs by coulter counter method	[PMID: 22119151]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by coulter counting Cytotoxicity against human leukemia cells after 48 hrs by coulter counting	[PMID: 22056277]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Growth inhibition of human leukemia cells after 48 hrs by SRB assay Growth inhibition of human leukemia cells after 48 hrs by SRB assay	[PMID: 27554444]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-fu	Antitumor activity against human leukemia cells after 48 hrs by SRB assay Antitumor activity against human leukemia cells after 48 hrs by SRB assay	[PMID: 20350811]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells at 10 uM after 48 hrs Cytotoxicity against human leukemia cells at 10 uM after 48 hrs	[PMID: 24469112]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-fu	Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Lewis lung carcinoma cell line	IC₅₀	2.59 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay	[PMID: 18440233]
Lewis lung carcinoma cell line	IC₅₀	2.9 μg/mL Compound: 5-Fu	Anticancer activity against mouse LL/2 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against mouse LL/2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
LFCl2A	IC₅₀	28.5 μM Compound: 5-fluoro uracil	In vitro cytotoxic activity against LFCl2A cell line derived from an hepatocarcinoma induced in the commentary rat by dimethylaminoazobenzene In vitro cytotoxic activity against LFCl2A cell line derived from an hepatocarcinoma induced in the commentary rat by dimethylaminoazobenzene	10.1016/S0960-894X(00)80263-2
LNCaP	IC₅₀	0.03 μM Compound: 5-FU	Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay	[PMID: 27156770]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against prostate cancer LNCaP Cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer LNCaP Cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer LNCaP cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer LNCaP cell line by sulforhodamine B assay	[PMID: 16005217]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate LNCaP cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate LNCaP cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
LNCaP	IC₅₀	47.18 μM Compound: F	Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
LNCaP	IC₅₀	5.21 μM Compound: 5-FU	Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay	[PMID: 28666860]
LNCaP C4-2B	IC₅₀	38.2 μM Compound: 5-FU	Antiproliferative activity against human C4-2B cells after 48 hrs by MTT assay Antiproliferative activity against human C4-2B cells after 48 hrs by MTT assay	[PMID: 30108895]
LNCaP C4-2B	IC₅₀	5.64 μM Compound: 5-fluorouracil	Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
LoVo	IC₅₀	11.5 μM Compound: 5-FU	Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay	[PMID: 30106289]
LoVo	IC₅₀	12.6 μM Compound: 5-FU	Anticancer activity against human LoVo cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human LoVo cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
LoVo	IC₅₀	12.7 μM Compound: 5-Fu	Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
LoVo	IC₅₀	2.7 μM Compound: 5-FU	Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
LoVo	IC₅₀	3.3 μM Compound: 5-Fu	Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay	[PMID: 22840493]
LoVo	IC₅₀	4.69 μM Compound: FUra	Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
LoVo	IC₅₀	8.35 μM Compound: 5-FU	Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
LOX IMVI	GI₅₀	0.24 μM Compound: 5-FU	Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
LS180	IC₅₀	38.92 μM Compound: FUra	Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
M14	GI₅₀	0.7 μg/mL Compound: 5FU	Cytotoxicity against human M14 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human M14 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
M14	GI₅₀	0.98 μM Compound: 5-FU	Anticancer activity against human M14 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human M14 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
M14	GI₅₀	0.98 μM Compound: 5-FU	Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
M14	GI₅₀	22.4 μM Compound: 5FU	Cytotoxicity against human M14 cells after 48 hrs Cytotoxicity against human M14 cells after 48 hrs	[PMID: 18798609]
Mahlavu	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 29326016]
Mahlavu	IC₅₀	10 μM Compound: 5-Fu	Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 22409771]
Malme-3M	GI₅₀	0.05 μM Compound: 5-FU	Anticancer activity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
Malme-3M	GI₅₀	0.05 μM Compound: 5-FU	Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MCF-10A	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MCF-10A	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
MCF-10A	IC₅₀	0.73 μM Compound: 5-FU	Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
MCF-10A	IC₅₀	17.2 μM Compound: 5-FU	Antiproliferation activity against human MCF-10A cells assessed as reduction in cell viability under hypoxic conditions by MTT assay Antiproliferation activity against human MCF-10A cells assessed as reduction in cell viability under hypoxic conditions by MTT assay	[PMID: 33965860]
MCF-10A	IC₅₀	39.7 μM Compound: 5-FU	Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33166925]
MCF-10A	IC₅₀	8.06 μM Compound: 5-Fu	Cytotoxicity against human MCF10A cells after 3 days by SRB assay Cytotoxicity against human MCF10A cells after 3 days by SRB assay	[PMID: 24704691]
MCF7	GI₅₀	> 10 μM Compound: 5-Fu	Growth inhibition of human MCF7 cells after 72 hrs by Alamar Blue assay Growth inhibition of human MCF7 cells after 72 hrs by Alamar Blue assay	[PMID: 19406645]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31803401]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against drug-resistant TCCD-induced human MCF7 cells overexpressing CYP1B1 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against drug-resistant TCCD-induced human MCF7 cells overexpressing CYP1B1 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31803401]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Antitumor activity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay Antitumor activity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 23313635]
MCF7	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22537362]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human MCF7 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
MCF7	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MCF7	IC₅₀	> 200 μM Compound: 5-FLU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 34606997]
MCF7	IC₅₀	0.0052 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as growth inhibition after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as growth inhibition after 72 hr by MTT assay	10.1007/s00044-012-0181-0
MCF7	IC₅₀	0.02 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
MCF7	IC₅₀	0.0415 mM Compound: 5-Fluorouracil	Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
MCF7	GI₅₀	0.07 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MCF7	GI₅₀	0.07 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MCF7	IC₅₀	0.09 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 26617970]
MCF7	IC₅₀	0.12 x 10^-2 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 16038565]
MCF7	ED₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 16309328]
MCF7	GI₅₀	0.3 μg/mL Compound: 5FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
MCF7	IC₅₀	0.3 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 19743863]
MCF7	IC₅₀	0.3 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs	[PMID: 17548198]
MCF7	IC₅₀	0.59 μM Compound: 5-FU	Antiproliferative activity against human MCF-7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Antiproliferative activity against human MCF-7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 32485532]
MCF7	IC₅₀	0.67 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22154835]
MCF7	IC₅₀	0.67 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 19932530]
MCF7	IC₅₀	0.69 mg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 3 days MTT assay Cytotoxicity against human MCF7 cells after 3 days MTT assay	[PMID: 22796042]
MCF7	IC₅₀	0.9 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
MCF7	IC₅₀	1.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 24060486]
MCF7	IC₅₀	1.25 μM Compound: 5-Florouracil	Anticancer activity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay Anticancer activity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay	10.1007/s00044-012-0260-2
MCF7	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 24835633]
MCF7	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 30108969]
MCF7	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
MCF7	IC₅₀	1.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 18606546]
MCF7	IC₅₀	1.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT microassay Cytotoxicity against human MCF7 cells by MTT microassay	[PMID: 17320246]
MCF7	GI₅₀	1.67 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 28400235]
MCF7	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition by MTT assay	[PMID: 34000484]
MCF7	IC₅₀	1.75 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 28165738]
MCF7	IC₅₀	1.8 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
MCF7	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells by MTT assay Antiproliferative activity against human MCF7 cells by MTT assay	[PMID: 29798826]
MCF7	IC₅₀	1.9 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
MCF7	IC₅₀	10.14 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23685571]
MCF7	IC₅₀	10.2 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
MCF7	IC₅₀	10.4 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
MCF7	IC₅₀	10.6 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
MCF7	IC₅₀	10.8 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
MCF7	IC₅₀	10.92 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
MCF7	IC₅₀	11.1 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis	[PMID: 27234893]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 2 days by MTT assay Cytotoxicity against human MCF7 cells after 2 days by MTT assay	[PMID: 24767839]
MCF7	IC₅₀	11.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Growth inhibition against human MCF7 cells after 48 hrs by MTT assay Growth inhibition against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23999046]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23558238]
MCF7	IC₅₀	12.1 μg/mL Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
MCF7	IC₅₀	12.24 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 25707012]
MCF7	IC₅₀	12.3 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
MCF7	IC₅₀	12.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22727445]
MCF7	IC₅₀	12.5 μM Compound: 5-FU	Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability under hypoxic conditions by MTT assay Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability under hypoxic conditions by MTT assay	[PMID: 33965860]
MCF7	IC₅₀	12.6 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
MCF7	IC₅₀	13.16 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
MCF7	IC₅₀	13.19 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
MCF7	IC₅₀	13.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27133593]
MCF7	IC₅₀	13.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
MCF7	IC₅₀	136.5 μM Compound: 5-FU	Cytotoxicity in human MCF-7 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human MCF-7 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
MCF7	IC₅₀	14 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22130132]
MCF7	IC₅₀	14.1 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 21109433]
MCF7	IC₅₀	14.2 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22749192]
MCF7	IC₅₀	14.26 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay	[PMID: 25442303]
MCF7	GI₅₀	14.5 nM Compound: 5FU	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 23094992]
MCF7	IC₅₀	14.7 μM Compound: 5-Fu	Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
MCF7	IC₅₀	15 μM Compound: 5 Fluorouracil	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
MCF7	IC₅₀	15 μM Compound: 5-FU	Antitumor activity against human MCF7 cells after 24 hrs by MTT assay Antitumor activity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 20211564]
MCF7	IC₅₀	15 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19919065]
MCF7	IC₅₀	15 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19795843]
MCF7	IC₅₀	15 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19618920]
MCF7	GI₅₀	15 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19572613]
MCF7	IC₅₀	15 μM Compound: 5-Fluorouracil	Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22405290]
MCF7	IC₅₀	15 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 72 hrs by MTT assay Growth inhibition of human MCF7 cells after 72 hrs by MTT assay	[PMID: 18640746]
MCF7	IC₅₀	15 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test	[PMID: 21530016]
MCF7	IC₅₀	15.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
MCF7	IC₅₀	15.2 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 3 days by MTT assay Cytotoxicity against human MCF7 cells after 3 days by MTT assay	[PMID: 21144621]
MCF7	IC₅₀	15.2 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
MCF7	IC₅₀	15.78 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 29486954]
MCF7	IC₅₀	16.2 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22840493]
MCF7	IC₅₀	16.27 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay	[PMID: 32135407]
MCF7	IC₅₀	16.28 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
MCF7	IC₅₀	16.3 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
MCF7	IC₅₀	16.32 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
MCF7	IC₅₀	16.7 μM Compound: 5-FU	Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
MCF7	IC₅₀	16.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23490159]
MCF7	IC₅₀	166 μM Compound: 5-FLU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 34606997]
MCF7	IC₅₀	17.11 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
MCF7	IC₅₀	17.2 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23279864]
MCF7	IC₅₀	178 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
MCF7	IC₅₀	18.13 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
MCF7	IC₅₀	18.58 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
MCF7	IC₅₀	18.75 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29475156]
MCF7	IC₅₀	19.2 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28073676]
MCF7	IC₅₀	19.39 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26363869]
MCF7	IC₅₀	2 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26854375]
MCF7	IC₅₀	2.13 μM Compound: 5-Fluorouracil	Cytotoxicity activity against human MCF7 cells incubated for 48 hrs by SRB assay Cytotoxicity activity against human MCF7 cells incubated for 48 hrs by SRB assay	[PMID: 34119830]
MCF7	IC₅₀	2.19 μg/mL Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29100732]
MCF7	IC₅₀	2.2 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 22011319]
MCF7	IC₅₀	2.2 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay	[PMID: 34875389]
MCF7	IC₅₀	2.3 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 22204901]
MCF7	IC₅₀	2.3 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
MCF7	IC₅₀	2.3 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against human MCF7 cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
MCF7	IC₅₀	2.35 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29223098]
MCF7	IC₅₀	2.36 μM Compound: 5-Fluorouracil	Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
MCF7	IC₅₀	2.46 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay	[PMID: 34847409]
MCF7	IC₅₀	2.5 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 23022735]
MCF7	GI₅₀	2.8 μM Compound: 5FU	Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
MCF7	IC₅₀	2.86 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 3 days by SRB assay Cytotoxicity against human MCF7 cells after 3 days by SRB assay	[PMID: 24704691]
MCF7	IC₅₀	2.9 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) MCF7 cells by SRB assay Cytotoxicity against Homo sapiens (human) MCF7 cells by SRB assay	10.1007/s00044-010-9500-5
MCF7	IC₅₀	20.09 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay	[PMID: 33894490]
MCF7	IC₅₀	21.11 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
MCF7	IC₅₀	21.47 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
MCF7	IC₅₀	22.439 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34000485]
MCF7	IC₅₀	22.6 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30527868]
MCF7	IC₅₀	22.8 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 34883453]
MCF7	IC₅₀	222.6 μM Compound: 5-Fuorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27017265]
MCF7	IC₅₀	24.58 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 22801644]
MCF7	IC₅₀	26.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28110871]
MCF7	IC₅₀	26.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30142612]
MCF7	IC₅₀	26.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
MCF7	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human MCF7 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
MCF7	IC₅₀	26.57 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30677614]
MCF7	IC₅₀	26.65 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
MCF7	IC₅₀	26.65 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
MCF7	IC₅₀	26.67 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
MCF7	IC₅₀	26.9 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells after 48 hrs by MTT assay Anticancer activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 25462264]
MCF7	IC₅₀	26.91 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29635169]
MCF7	IC₅₀	27.89 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30243153]
MCF7	IC₅₀	28.73 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 28458133]
MCF7	IC₅₀	28.97 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 29174813]
MCF7	IC₅₀	29.4 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30108895]
MCF7	IC₅₀	29.41 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
MCF7	IC₅₀	29.5 μM Compound: 5-FU	Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
MCF7	IC₅₀	3 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27343853]
MCF7	IC₅₀	3 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 29326016]
MCF7	IC₅₀	3.15 μM Compound: 5-fluorouracil	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 32311607]
MCF7	IC₅₀	3.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28666860]
MCF7	IC₅₀	3.2 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 31471102]
MCF7	IC₅₀	3.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 24332497]
MCF7	IC₅₀	3.5 μM Compound: 5FU	Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
MCF7	IC₅₀	3.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 22409771]
MCF7	IC₅₀	3.52 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 24835817]
MCF7	GI₅₀	3.6 μM Compound: 5-FU	Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay	[PMID: 27504537]
MCF7	IC₅₀	3.6 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23792763]
MCF7	IC₅₀	30 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells by MTT assay Antiproliferative activity against human MCF7 cells by MTT assay	[PMID: 31546197]
MCF7	IC₅₀	30 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 28371676]
MCF7	IC₅₀	30.41 μM Compound: Fluorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27128180]
MCF7	IC₅₀	31.04 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells overexpressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against human MCF7 cells overexpressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 27575478]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 26703795]
MCF7	IC₅₀	32.18 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23665106]
MCF7	IC₅₀	32.27 μM Compound: F	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
MCF7	IC₅₀	32.626 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 29223717]
MCF7	IC₅₀	34 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay	[PMID: 20961091]
MCF7	IC₅₀	34.48 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay	[PMID: 25466196]
MCF7	IC₅₀	35 μM Compound: 5-fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22304344]
MCF7	IC₅₀	38.5 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28756264]
MCF7	IC₅₀	39.88 μM Compound: Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 25016234]
MCF7	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 19560842]
MCF7	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Antiproliferative activity in human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity in human MCF7 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay	[PMID: 21126804]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 3 days by SRB assay Antiproliferative activity against human MCF7 cells after 3 days by SRB assay	[PMID: 18069093]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
MCF7	IC₅₀	4.42 μM Compound: 5-FU	Antitumor activity against human MCF7 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human MCF7 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
MCF7	IC₅₀	4.5 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 3 days by MTT assay Antiproliferative activity against human MCF7 cells after 3 days by MTT assay	[PMID: 18424155]
MCF7	GI₅₀	4.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 27688184]
MCF7	IC₅₀	4.55 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
MCF7	IC₅₀	4.6 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
MCF7	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining	[PMID: 22959205]
MCF7	IC₅₀	4.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 after 72 hrs by MTT assay Cytotoxicity against human MCF7 after 72 hrs by MTT assay	[PMID: 19233650]
MCF7	IC₅₀	4.7 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method	[PMID: 22450132]
MCF7	IC₅₀	4.7 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method	[PMID: 22765897]
MCF7	IC₅₀	4.76 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
MCF7	IC₅₀	4.8 μg/mL Compound: 5-flourouracil	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27597407]
MCF7	IC₅₀	4.8 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 17336074]
MCF7	IC₅₀	41.51 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 31401008]
MCF7	IC₅₀	42.01 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21524829]
MCF7	IC₅₀	42.78 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26883148]
MCF7	IC₅₀	42.78 μM Compound: 5FU	Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
MCF7	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23800391]
MCF7	IC₅₀	5.012 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26301558]
MCF7	IC₅₀	5.05 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
MCF7	IC₅₀	5.2 x 10^-1 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay	[PMID: 26725029]
MCF7	IC₅₀	5.2 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
MCF7	IC₅₀	5.32 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
MCF7	IC₅₀	5.4 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35694689]
MCF7	IC₅₀	5.4 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31276896]
MCF7	IC₅₀	5.44 μM Compound: 5-Fu	Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
MCF7	IC₅₀	5.6 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
MCF7	IC₅₀	5.7 μM Compound: 5-Fluorouracil	Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
MCF7	IC₅₀	5.8 μM Compound: 5-FU	Cytotoxicity against ERalpha-dependent human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against ERalpha-dependent human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33166925]
MCF7	IC₅₀	52.07 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
MCF7	IC₅₀	57 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 31057737]
MCF7	IC₅₀	57.09 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30108924]
MCF7	IC₅₀	6.11 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29254641]
MCF7	GI₅₀	6.5 μM Compound: 5FU	Cytotoxicity against human MCF7 cells after 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs	[PMID: 18798609]
MCF7	IC₅₀	6.53 μM Compound: FUra	Cytotoxicity against human MCF7cells after 72 hrs by SRB assay Cytotoxicity against human MCF7cells after 72 hrs by SRB assay	[PMID: 27073055]
MCF7	IC₅₀	6.53 μM Compound: FUra	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 23867603]
MCF7	IC₅₀	6.53 μM Compound: FUra	Cytotoxicity against human MCF7 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
MCF7	IC₅₀	63 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 29908443]
MCF7	IC₅₀	64 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
MCF7	IC₅₀	66.91 μM Compound: 5-Fluoruracil	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22555152]
MCF7	IC₅₀	7.08 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 24819956]
MCF7	IC₅₀	7.12 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 27987485]
MCF7	IC₅₀	7.12 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells after 72 hrs by MTT assay Anticancer activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 25001482]
MCF7	IC₅₀	7.21 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 28759876]
MCF7	IC₅₀	7.33 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23644193]
MCF7	IC₅₀	7.42 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
MCF7	IC₅₀	7.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31546197]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23792764]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Antitumor activity against human MCF7 cells after 72 hrs by MTT assay Antitumor activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21486694]
MCF7	IC₅₀	7.61 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
MCF7	IC₅₀	7.67 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
MCF7	IC₅₀	7.76 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 24798098]
MCF7	IC₅₀	7.8 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay	[PMID: 30248657]
MCF7	IC₅₀	71.49 μM Compound: 2; 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27322756]
MCF7	CC₅₀	768.8 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 18037195]
MCF7	CC₅₀	768.8 μM Compound: 5FU	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 17548129]
MCF7	CC₅₀	768.8 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 17337193]
MCF7	IC₅₀	78.28 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 48 hrs by WST1 assay Growth inhibition of human MCF7 cells after 48 hrs by WST1 assay	[PMID: 28126436]
MCF7	IC₅₀	78.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells by MTT reduction assay Antiproliferative activity against human MCF7 cells by MTT reduction assay	[PMID: 33421712]
MCF7	IC₅₀	78.6 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23067549]
MCF7	IC₅₀	79.3 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	10.1039/C6MD00234J
MCF7	GI₅₀	8.3 μM Compound: 5-fluorouracil	Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
MCF7	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
MCF7	IC₅₀	8.41 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 35609396]
MCF7	IC₅₀	8.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
MCF7	IC₅₀	8.77 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
MCF7	IC₅₀	8.93 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
MCF7	IC₅₀	9.12 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
MCF7	IC₅₀	9.25 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 27771599]
MCF7	IC₅₀	9.49 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
MCF7	IC₅₀	9.56 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
MCF7	IC₅₀	9.6 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs	[PMID: 21295381]
MCF7	IC₅₀	9.67 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22079378]
MCF7	IC₅₀	9.79 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 24286761]
MCF7	GI₅₀	9.9 μM Compound: 5-Fu	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 22512908]
MDA-MB-231	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
MDA-MB-231	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
MDA-MB-231	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
MDA-MB-231	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
MDA-MB-231	IC₅₀	1.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
MDA-MB-231	IC₅₀	10.22 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MDA-MB-231	IC₅₀	13 μM Compound: 5-FU	Anticancer activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Anticancer activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33940466]
MDA-MB-231	IC₅₀	13.65 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 23920246]
MDA-MB-231	IC₅₀	13.65 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay	[PMID: 22579780]
MDA-MB-231	IC₅₀	15 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay	[PMID: 34516133]
MDA-MB-231	IC₅₀	15.74 μM Compound: 5-FU	Cytotoxicity against Non-ERalpha-dependent human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against Non-ERalpha-dependent human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33166925]
MDA-MB-231	IC₅₀	16.117 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 72 hrs by MTT assay	[PMID: 34000485]
MDA-MB-231	IC₅₀	17.74 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
MDA-MB-231	IC₅₀	18.12 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay	[PMID: 24704691]
MDA-MB-231	IC₅₀	19 μM Compound: 5 Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
MDA-MB-231	IC₅₀	2.45 μM Compound: FU	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 24941129]
MDA-MB-231	IC₅₀	2.72 μM Compound: 5-Fluorouracil	Cytotoxicity against Homo sapiens (human) MDA231 cells assessed as inhibition of cell growth after 48 hr by MTT assay Cytotoxicity against Homo sapiens (human) MDA231 cells assessed as inhibition of cell growth after 48 hr by MTT assay	10.1007/s00044-012-0209-5
MDA-MB-231	IC₅₀	20 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
MDA-MB-231	IC₅₀	21.05 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 30318440]
MDA-MB-231	IC₅₀	22.53 μM Compound: 2; 5-FU	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 27322756]
MDA-MB-231	IC₅₀	24.5 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
MDA-MB-231	IC₅₀	24.6 μM Compound: Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 27128180]
MDA-MB-231	IC₅₀	24.6 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 25016234]
MDA-MB-231	IC₅₀	25 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 34171512]
MDA-MB-231	IC₅₀	25.31 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay	[PMID: 33894490]
MDA-MB-231	IC₅₀	26.73 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35797901]
MDA-MB-231	IC₅₀	29.38 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay	[PMID: 33129590]
MDA-MB-231	IC₅₀	3.5 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay	[PMID: 34847409]
MDA-MB-231	IC₅₀	3.5 μM Compound: 5-FU	Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
MDA-MB-231	IC₅₀	31.57 μM Compound: 5-Fu	Cytotoxicity against human MDA231 cells by MTT assay Cytotoxicity against human MDA231 cells by MTT assay	[PMID: 22801644]
MDA-MB-231	IC₅₀	35.91 μM Compound: 5-FU	Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
MDA-MB-231	IC₅₀	35.91 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
MDA-MB-231	IC₅₀	35.98 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
MDA-MB-231	IC₅₀	4.33 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 28431881]
MDA-MB-231	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs	[PMID: 21295381]
MDA-MB-231	IC₅₀	4.75 μM Compound: 5-fluoro uracil	Cytotoxicity against human MDA-MB-231 cells incubated for 3 days by MTT assay Cytotoxicity against human MDA-MB-231 cells incubated for 3 days by MTT assay	[PMID: 33152379]
MDA-MB-231	IC₅₀	45.43 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 27397498]
MDA-MB-231	IC₅₀	45.43 μM Compound: 5-FU	Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 26413726]
MDA-MB-231	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 27987485]
MDA-MB-231	IC₅₀	5.2 μM Compound: 5-fluorouracil	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay	[PMID: 25919052]
MDA-MB-231	IC₅₀	5.2 μM Compound: 5-FU	Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay	[PMID: 27311895]
MDA-MB-231	IC₅₀	5.82 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 25870131]
MDA-MB-231	IC₅₀	5.85 μM Compound: 5-Fu	Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
MDA-MB-231	IC₅₀	53.47 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 28789892]
MDA-MB-231	GI₅₀	54 μM Compound: 5-fluorouracil	Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay	[PMID: 20438092]
MDA-MB-231	GI₅₀	6.6 μM Compound: 5-FU	Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MDA-MB-231	GI₅₀	6.6 μM Compound: 5-FU	Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MDA-MB-231	IC₅₀	66.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 24 hrs Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 24 hrs	[PMID: 33139111]
MDA-MB-231	IC₅₀	7.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31546197]
MDA-MB-231	IC₅₀	7.75 μM Compound: 5-FU	Antitumor activity against human MDA-MB-231 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human MDA-MB-231 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
MDA-MB-231	IC₅₀	77.28 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay	[PMID: 25466196]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining	[PMID: 22959205]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method	[PMID: 22450132]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method	[PMID: 22765897]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-231 cells after 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs	[PMID: 17336074]
MDA-MB-231	IC₅₀	9.89 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay	[PMID: 32992255]
MDA-MB-231	IC₅₀	93.8 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31803401]
MDA-MB-435	GI₅₀	0.07 μM Compound: 5-FU	Anticancer activity against human MDA-MB-435 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MDA-MB-435 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MDA-MB-435	GI₅₀	0.07 μM Compound: 5-FU	Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MDA-MB-435	IC₅₀	25.6 μg/mL Compound: 5-F	Cytotoxicity against human MDA-MB-435 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells after 48 hrs by MTT assay	[PMID: 24342667]
MDA-MB-435S	IC₅₀	14.5 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay	[PMID: 23792763]
MDA-MB-435S	IC₅₀	14.5 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method	[PMID: 17524655]
MDA-MB-435S	IC₅₀	15.19 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay	[PMID: 26595184]
MDA-MB-435S	IC₅₀	15.2 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay	[PMID: 27537924]
MDA-MB-453	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-453 cells after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-453 cells after 72 hrs by MTT assay	[PMID: 22079378]
MDA-MB-468	IC₅₀	> 20 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay	[PMID: 34516133]
MDA-MB-468	IC₅₀	> 200 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35797901]
MDA-MB-468	IC₅₀	44.6 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
MDA-MB-468	IC₅₀	44.9 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
MDA-MB-468	IC₅₀	7.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31546197]
MDA-MB-468	IC₅₀	95.69 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-468 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-468 cells after 48 hrs by MTT assay	[PMID: 28789892]
ME-180	IC₅₀	4.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human ME180 cells after 48 hrs by MTT assay Cytotoxicity against human ME180 cells after 48 hrs by MTT assay	[PMID: 24332497]
Melanoma cell	CC₅₀	46.1 μM Compound: 5-Fu	Cytotoxicity against human melanoma cells after 72 hrs Cytotoxicity against human melanoma cells after 72 hrs	[PMID: 18037195]
Melanoma cell	CC₅₀	46.1 μM Compound: 5FU	Cytotoxicity against human melanoma cells after 72 hrs Cytotoxicity against human melanoma cells after 72 hrs	[PMID: 17548129]
Melanoma cell	CC₅₀	46.1 μM Compound: 5-FU	Cytotoxicity against human skin melanoma cells after 72 hrs Cytotoxicity against human skin melanoma cells after 72 hrs	[PMID: 17337193]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by coulter counter analysis Cytotoxicity against human melanoma cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Growth inhibition of human Melanoma cells after 48 hrs by coulter counter method Growth inhibition of human Melanoma cells after 48 hrs by coulter counter method	[PMID: 22119151]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by coulter counting Cytotoxicity against human melanoma cells after 48 hrs by coulter counting	[PMID: 22056277]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Growth inhibition of human melanoma cells after 48 hrs by SRB assay Growth inhibition of human melanoma cells after 48 hrs by SRB assay	[PMID: 27554444]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by SRB assay Cytotoxicity against human melanoma cells after 48 hrs by SRB assay	[PMID: 23994328]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-fu	Antitumor activity against human melanoma cells after 48 hrs by SRB assay Antitumor activity against human melanoma cells after 48 hrs by SRB assay	[PMID: 20350811]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells at 10 uM after 48 hrs Cytotoxicity against human melanoma cells at 10 uM after 48 hrs	[PMID: 24469112]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human melanoma cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-fu	Antiproliferative activity against human melanoma cells after 48 hrs by cell counting analysis Antiproliferative activity against human melanoma cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Growth inhibition of human melanoma cells after 48 hrs Growth inhibition of human melanoma cells after 48 hrs	[PMID: 18950904]
MES-SA	IC₅₀	1.1 μM Compound: 5-FU	Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay	[PMID: 19743863]
MeWo	IC₅₀	8 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human MeWo cells by MTT assay Cytotoxicity against human MeWo cells by MTT assay	[PMID: 29280630]
MFE-296	IC₅₀	30.68 μM Compound: 5FU	Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
MG-63	IC₅₀	8 μM Compound: 5-FU	Cytotoxicity against human MG63 cells after 3 days by MTT assay Cytotoxicity against human MG63 cells after 3 days by MTT assay	[PMID: 21612935]
MGC-803	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 29174813]
MGC-803	IC₅₀	> 50 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 30677614]
MGC-803	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human MGC-803 cells incubated for 72 hrs by MTT assay Anticancer activity against human MGC-803 cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
MGC-803	IC₅₀	1.25 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
MGC-803	IC₅₀	1.8 μg/mL Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29100732]
MGC-803	IC₅₀	10 μM Compound: 5-Fu	Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
MGC-803	IC₅₀	10.14 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
MGC-803	IC₅₀	10.14 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
MGC-803	IC₅₀	10.27 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
MGC-803	IC₅₀	10.64 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
MGC-803	IC₅₀	10.72 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 25707012]
MGC-803	IC₅₀	11.34 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 24835817]
MGC-803	IC₅₀	12.14 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
MGC-803	IC₅₀	12.6 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 3 days by MTT assay Cytotoxicity against human MGC803 cells after 3 days by MTT assay	[PMID: 21144621]
MGC-803	IC₅₀	14 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human MGC803 cells assessed as reduction in cell viability by MTT assay	[PMID: 31029946]
MGC-803	IC₅₀	14.15 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 29133051]
MGC-803	IC₅₀	15.32 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 24211021]
MGC-803	IC₅₀	16.6 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 22079378]
MGC-803	IC₅₀	18.5 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 22749192]
MGC-803	IC₅₀	18.63 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells measured after 48 hrs by MTT assay	[PMID: 32135407]
MGC-803	IC₅₀	24.803 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells by MTT assay Antiproliferative activity against human MGC-803 cells by MTT assay	[PMID: 32810752]
MGC-803	IC₅₀	25.54 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29316536]
MGC-803	IC₅₀	27.56 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
MGC-803	IC₅₀	28.6 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 35286954]
MGC-803	IC₅₀	29.15 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
MGC-803	IC₅₀	3.12 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 28165738]
MGC-803	EC₅₀	3.35 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 26883149]
MGC-803	IC₅₀	3.38 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay	[PMID: 31404863]
MGC-803	IC₅₀	3.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 22405648]
MGC-803	IC₅₀	3.45 μM Compound: 5-Fu	Anticancer activity against human MGC803 cells after 72 hrs by MTT assay Anticancer activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 25001482]
MGC-803	IC₅₀	3.58 μM Compound: 5-Fluorouracil	Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
MGC-803	IC₅₀	3.68 μM Compound: 5-Fluorouracil	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 24119869]
MGC-803	IC₅₀	3.71 μM Compound: 5-Fluorouracil	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 25554922]
MGC-803	IC₅₀	3.79 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
MGC-803	IC₅₀	30.45 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 25462253]
MGC-803	IC₅₀	31.04 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 30142612]
MGC-803	IC₅₀	34.85 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells by MTT assay Antiproliferative activity against human MGC-803 cells by MTT assay	[PMID: 33109400]
MGC-803	IC₅₀	39.1 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
MGC-803	IC₅₀	4.55 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
MGC-803	IC₅₀	40.94 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
MGC-803	IC₅₀	46.93 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 25151580]
MGC-803	IC₅₀	46.93 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 24953029]
MGC-803	IC₅₀	47.39 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 2 days by MTT assay Cytotoxicity against human MGC803 cells after 2 days by MTT assay	[PMID: 25841196]
MGC-803	IC₅₀	5.81 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
MGC-803	IC₅₀	58 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 31057737]
MGC-803	IC₅₀	6.06 μM Compound: 5-FU	Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
MGC-803	IC₅₀	6.22 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34455358]
MGC-803	IC₅₀	6.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MGC803 cells by MTT assay Antiproliferative activity against human MGC803 cells by MTT assay	[PMID: 31546197]
MGC-803	IC₅₀	6.52 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
MGC-803	IC₅₀	6.56 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 30108876]
MGC-803	IC₅₀	6.56 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 28456031]
MGC-803	IC₅₀	6.82 μM Compound: 5-FU	Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
MGC-803	IC₅₀	6.82 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32682200]
MGC-803	IC₅₀	6.89 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 28759876]
MGC-803	IC₅₀	6.92 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
MGC-803	IC₅₀	6.92 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 23792764]
MGC-803	IC₅₀	62.51 μM Compound: 5-Fu	Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
MGC-803	IC₅₀	68.3 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 26714048]
MGC-803	IC₅₀	7.01 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
MGC-803	IC₅₀	7.14 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 23644193]
MGC-803	IC₅₀	7.21 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 28038329]
MGC-803	IC₅₀	7.21 μM Compound: 5-Fu	Antitumor activity human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36216031]
MGC-803	IC₅₀	7.21 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27423479]
MGC-803	IC₅₀	7.22 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	10.1039/C6MD00169F
MGC-803	IC₅₀	7.35 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 27771599]
MGC-803	IC₅₀	7.52 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
MGC-803	IC₅₀	7.52 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28863355]
MGC-803	IC₅₀	7.52 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28838695]
MGC-803	IC₅₀	7.54 μM Compound: 5-FU	Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MGC-803	IC₅₀	7.69 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
MGC-803	IC₅₀	7.76 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
MGC-803	IC₅₀	7.86 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29407946]
MGC-803	IC₅₀	74.39 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 30108924]
MGC-803	IC₅₀	8.13 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 24798098]
MGC-803	IC₅₀	8.43 μM Compound: 5-Fu	Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
MGC-803	IC₅₀	8.66 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
MGC-803	IC₅₀	8.66 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29635165]
MGC-803	IC₅₀	9.05 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
MGC-803	IC₅₀	9.2 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
MGC-803	IC₅₀	9.24 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29475156]
MGC-803	IC₅₀	9.79 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 31740251]
MGC-803	IC₅₀	9.79 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28763643]
MGC-803	IC₅₀	93.53 μM Compound: 5-FU	Cytotoxicity in human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
M-HeLa	IC₅₀	62 μM Compound: 5-Fluorouracil	Cytotoxicity against human HelaM cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human HelaM cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
MIA PaCa-2	GI₅₀	> 10 μM Compound: 5-Fu	Growth inhibition of human MIAPaCa2 cells after 72 hrs by Alamar Blue assay Growth inhibition of human MIAPaCa2 cells after 72 hrs by Alamar Blue assay	[PMID: 19406645]
MIA PaCa-2	IC₅₀	10 μM Compound: 5-FU	Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay	[PMID: 18640746]
MIA PaCa-2	IC₅₀	11.45 μM Compound: 5-FU	Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay	[PMID: 21524829]
MIA PaCa-2	IC₅₀	11.67 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
MIA PaCa-2	IC₅₀	11.67 μM Compound: 5-Fluoruracil	Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay	[PMID: 22555152]
MIA PaCa-2	IC₅₀	14 μM Compound: 5-FU	Antiproliferative activity against human MIAPaCa2 cells after 48 hrs Antiproliferative activity against human MIAPaCa2 cells after 48 hrs	[PMID: 21458113]
MIA PaCa-2	IC₅₀	24.267 μM Compound: 5-Fluorouracil	Cytotoxicity against human MIAPaCa2 cells incubated for 24 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
MIA PaCa-2	IC₅₀	3.5 μg/mL Compound: 5-Fu	Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
MIA PaCa-2	GI₅₀	30 μM Compound: 5-Fu	Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay	[PMID: 22512908]
MIA PaCa-2	GI₅₀	30.6 nM Compound: 5FU	Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay	[PMID: 23094992]
MIA PaCa-2	IC₅₀	6.5 μM Compound: 5-FU	Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay	[PMID: 18424155]
MIA PaCa-2	IC₅₀	7.4 μM Compound: 5-FU	Antiproliferative activity against human MIAPaCa2 cells after 72 hrs Antiproliferative activity against human MIAPaCa2 cells after 72 hrs	[PMID: 21458113]
MKN-28	IC₅₀	6.9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MKN28 cells by MTT assay Antiproliferative activity against human MKN28 cells by MTT assay	[PMID: 31546197]
MKN-28	IC₅₀	9.67 μM Compound: 5-fluorouracil	Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25506718]
MKN-45	IC₅₀	21.4 μM Compound: 5-FU	Cytotoxicity against human MNK45 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human MNK45 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
MKN-45	IC₅₀	3.6 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human MKN45 cells by MTT assay Cytotoxicity against human MKN45 cells by MTT assay	[PMID: 22011319]
MKN-45	IC₅₀	41.73 μM Compound: Fluorouracil	Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay	[PMID: 22809558]
MKN-45	IC₅₀	6.9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MKN45 cells by MTT assay Antiproliferative activity against human MKN45 cells by MTT assay	[PMID: 31546197]
MKN-45	IC₅₀	8.89 μM Compound: 5-Fu	Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
MKN-45	IC₅₀	8.89 μM Compound: 5-FU	Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay	[PMID: 28863355]
MKN-45	IC₅₀	8.89 μM Compound: 5-FU	Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay	[PMID: 28838695]
MOLT-3	ED₅₀	2.14 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human TMOLT3 cells after 3 days by trypan blue exclusion technique Cytotoxicity against human TMOLT3 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
MOLT-4	IC₅₀	0.03 μM Compound: 5-FU	Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay	[PMID: 20211564]
MOLT-4	GI₅₀	0.35 μM Compound: 5-FU	Anticancer activity against human MOLT-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MOLT-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MOLT-4	GI₅₀	0.35 μM Compound: 5-FU	Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MOLT-4	ED₅₀	15.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT4 cells after 6 hrs by Alamar Blue assay Cytotoxicity against human MOLT4 cells after 6 hrs by Alamar Blue assay	[PMID: 24020806]
MOLT-4	IC₅₀	20 μM Compound: 5-FU	Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay	[PMID: 18424155]
MOLT-4	IC₅₀	3.2 μM Compound: 5-Fu	Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay	[PMID: 22424614]
MOLT-4	IC₅₀	6.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
MOLT-4	ED₅₀	7.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT4 cells by Alamar blue assay Cytotoxicity against human MOLT4 cells by Alamar blue assay	[PMID: 24128077]
Mononuclear cell line	IC₅₀	429.8 μM Compound: 5-FU	Cytotoxicity against patient-derived human mononuclear cells assessed as cell growth inhibition incubated for 72 hrs by FMCA assay Cytotoxicity against patient-derived human mononuclear cells assessed as cell growth inhibition incubated for 72 hrs by FMCA assay	[PMID: 36018000]
MRC5	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human MRC5 cells after 48 hrs by SRB assay Growth inhibition of human MRC5 cells after 48 hrs by SRB assay	[PMID: 28400235]
N2a	IC₅₀	1.2 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
NCI/ADR-RES	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity against multidrug-resistant human MCF7/ADR cells after 48 hrs by MTT assay Cytotoxicity against multidrug-resistant human MCF7/ADR cells after 48 hrs by MTT assay	[PMID: 22537362]
NCI/ADR-RES	GI₅₀	0.31 μM Compound: 5-FU	Anticancer activity against human NCI/ADR-RES cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI/ADR-RES cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI/ADR-RES	GI₅₀	0.31 μM Compound: 5-FU	Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI/ADR-RES	IC₅₀	512.78 μM Compound: 5-FU	Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay	[PMID: 30677614]
NCI/ADR-RES	IC₅₀	54.72 μM Compound: 5-FU	Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
NCI-H1299	IC₅₀	8.91 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay	[PMID: 28152430]
NCI-H1650	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
NCI-H1650	IC₅₀	12.52 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay	[PMID: 30108876]
NCI-H1650	IC₅₀	12.52 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay	[PMID: 28456031]
NCI-H1650	IC₅₀	14.25 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
NCI-H1650	IC₅₀	14.25 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay	[PMID: 28863355]
NCI-H1650	IC₅₀	14.25 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay	[PMID: 28838695]
NCI-H1650	IC₅₀	14.63 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay	[PMID: 29407946]
NCI-H1975	IC₅₀	2.67 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
NCI-H1975	IC₅₀	9.37 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
NCI-H226	GI₅₀	54.7 μM Compound: 5-FU	Anticancer activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H226	GI₅₀	54.7 μM Compound: 5-FU	Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H23	GI₅₀	0.33 μM Compound: 5-FU	Anticancer activity against human NCI-H23 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H23 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H23	GI₅₀	0.33 μM Compound: 5-FU	Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H358	IC₅₀	6.9 μg/mL Compound: 5-Fu	Cytotoxicity against human NCI-H358 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human NCI-H358 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
NCI-H460	GI₅₀	0.05 μM Compound: 5-FU	Anticancer activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H460	GI₅₀	0.05 μM Compound: 5-FU	Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H460	GI₅₀	0.3 μg/mL Compound: 5FU	Cytotoxicity against human H460 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human H460 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
NCI-H460	IC₅₀	0.54 μM Compound: 5-fluorouracil	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay	[PMID: 30660827]
NCI-H460	IC₅₀	11.75 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 30318440]
NCI-H460	IC₅₀	2 μM Compound: 5-FU	Antitumor activity against human H460 cells after 24 hrs by MTT assay Antitumor activity against human H460 cells after 24 hrs by MTT assay	[PMID: 20211564]
NCI-H460	IC₅₀	2 μM Compound: 5-FU	Growth inhibition of human H460 cells after 72 hrs by MTT assay Growth inhibition of human H460 cells after 72 hrs by MTT assay	[PMID: 18640746]
NCI-H460	IC₅₀	2.4 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 22727445]
NCI-H460	IC₅₀	2.48 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 24021891]
NCI-H460	IC₅₀	2.7 μM Compound: 5-FU	Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
NCI-H460	IC₅₀	23.32 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 24211021]
NCI-H460	IC₅₀	26.7 μM Compound: 5-FU	Cytotoxicity against human H460 cells after 48 hrs by MTT assay Cytotoxicity against human H460 cells after 48 hrs by MTT assay	[PMID: 23867385]
NCI-H460	IC₅₀	29 μM Compound: 5-fu	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 22304344]
NCI-H460	IC₅₀	3 μM Compound: 5-Fluorouracil	Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 22405290]
NCI-H460	IC₅₀	3 μM Compound: 5-FU	Cytotoxicity against human H460 cells after 72 hrs by MTT assay Cytotoxicity against human H460 cells after 72 hrs by MTT assay	[PMID: 22130132]
NCI-H460	IC₅₀	35.52 μM Compound: 5-FU	Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
NCI-H460	IC₅₀	36 μM Compound: 5-FU	Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 28756264]
NCI-H460	IC₅₀	36.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 25462253]
NCI-H460	IC₅₀	36.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 24565905]
NCI-H460	GI₅₀	4.1 μM Compound: 5FU	Cytotoxicity against human H460 cells after 48 hrs Cytotoxicity against human H460 cells after 48 hrs	[PMID: 18798609]
NCI-H460	IC₅₀	44.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay	[PMID: 24095745]
NCI-H460	IC₅₀	44.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 25151580]
NCI-H460	IC₅₀	44.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 23988357]
NCI-H460	IC₅₀	45.14 μM Compound: 5-Fu	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 24953029]
NCI-H460	IC₅₀	45.44 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 30108826]
NCI-H460	IC₅₀	45.44 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 30092368]
NCI-H460	IC₅₀	46.15 μM Compound: 5-Fu	Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay	[PMID: 25841196]
NCI-H460	GI₅₀	5.95 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
NCI-H460	GI₅₀	6.5 μM Compound: 5-Fu	Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay	[PMID: 22512908]
NCI-H460	IC₅₀	7.03 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth by CCK8 assay Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth by CCK8 assay	[PMID: 33964443]
NCI-H460	IC₅₀	7.2 μg/mL Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 22647218]
NCI-H460	IC₅₀	8.5 μM Compound: 5-FU	Antiproliferative activity against human NCI-H460 cells after 48 h by hrs MTT assay Antiproliferative activity against human NCI-H460 cells after 48 h by hrs MTT assay	[PMID: 29305189]
NCI-H460	IC₅₀	9.9 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
NCI-H508	IC₅₀	8.8 μM Compound: 5-FU	Antiproliferative activity against human NCI-H508 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human NCI-H508 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
NCI-H522	IC₅₀	55.6 μM Compound: 5-FU	Growth inhibition of human NCI-H522 cells after 24 hrs by MTT assay Growth inhibition of human NCI-H522 cells after 24 hrs by MTT assay	[PMID: 28011220]
NCI-H522	IC₅₀	56.76 μM Compound: 5-FU	Cytotoxicity against human NCI-H522 cells after 24 hrs by MTT assay Cytotoxicity against human NCI-H522 cells after 24 hrs by MTT assay	[PMID: 23202484]
NCI-H522	GI₅₀	7.27 μM Compound: 5-FU	Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H522	GI₅₀	7.27 μM Compound: 5-FU	Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H522	GI₅₀	7.28 μM Compound: 5-FU	Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay	[PMID: 22305543]
NCI-H69	IC₅₀	0.28 mg/mL Compound: 5-Fu	Cytotoxicity against human NCI-H69 cells after 3 days MTT assay Cytotoxicity against human NCI-H69 cells after 3 days MTT assay	[PMID: 22796042]
NCI-H69	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human NCI-H69 cells after 48 hrs by SRB assay Growth inhibition of human NCI-H69 cells after 48 hrs by SRB assay	[PMID: 22512908]
NCM460	EC₅₀	43.32 μM Compound: 5-FU	Cytotoxicity against human NCM460 cells assessed as cell viability measured after 72 hrs in presence of 5-FU by MTT assay Cytotoxicity against human NCM460 cells assessed as cell viability measured after 72 hrs in presence of 5-FU by MTT assay	[PMID: 34411894]
NHDF	IC₅₀	> 25 μM Compound: 5-Fluorouracil	Cytotoxicity against human NHDF cells incubated for 72 hrs by MTS assay Cytotoxicity against human NHDF cells incubated for 72 hrs by MTS assay	[PMID: 31158748]
NHDF	IC₅₀	14.67 μM Compound: 5-FU	Antiproliferative activity against NHDF expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against NHDF expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
NHDF	IC₅₀	30 μM Compound: 5-FU	Antiproliferative activity against NHDF expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against NHDF expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
NHDF	GI₅₀	62.02 nM Compound: 5FU	Growth inhibition of human NHDF cells after 48 hrs by SRB assay Growth inhibition of human NHDF cells after 48 hrs by SRB assay	[PMID: 23094992]
NHDF	IC₅₀	7.02 μM Compound: FUra	Cytotoxicity against HDF assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against HDF assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
NHDF	IC₅₀	7.38 μM Compound: 5-FU	Antiproliferative activity against NHDF after 72 hrs by MTT assay Antiproliferative activity against NHDF after 72 hrs by MTT assay	[PMID: 29223098]
NHDF	IC₅₀	70.4 μM Compound: 1; 5-FU	Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 33819035]
NIH3T3	GI₅₀	< 1.54 μM Compound: 5FU	Cytotoxicity against BALB mouse 3T3 cells after 48 hrs Cytotoxicity against BALB mouse 3T3 cells after 48 hrs	[PMID: 18798609]
NIH3T3	IC₅₀	22.36 μM Compound: 5-Fluorouracil	Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
NSCLC	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human NSCLC cells after 48 hrs by coulter counter method Growth inhibition of human NSCLC cells after 48 hrs by coulter counter method	[PMID: 22119151]
NSCLC	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human NSCLC cells after 48 hrs by coulter counting Cytotoxicity against human NSCLC cells after 48 hrs by coulter counting	[PMID: 22056277]
NSCLC	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human NSCLC cells after 48 hrs Growth inhibition of human NSCLC cells after 48 hrs	[PMID: 18950904]
Ovarian cancer cell line	IC₅₀	562.8 μM Compound: 5-FU	Anticancer activity against patient-derived human Ovarian tumor cells assessed as tumor growth inhibition incubated for 72 hrs by FMCA assay Anticancer activity against patient-derived human Ovarian tumor cells assessed as tumor growth inhibition incubated for 72 hrs by FMCA assay	[PMID: 36018000]
OVCAR-3	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
OVCAR-3	GI₅₀	0.01 μM Compound: 5-FU	Anticancer activity against human OVCAR-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-3	GI₅₀	0.01 μM Compound: 5-FU	Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-4	GI₅₀	4.43 μM Compound: 5-FU	Anticancer activity against human OVCAR-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-4	GI₅₀	4.43 μM Compound: 5-FU	Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-5	GI₅₀	10.9 μM Compound: 5-FU	Anticancer activity against human OVCAR-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-5	GI₅₀	10.9 μM Compound: 5-FU	Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-5	GI₅₀	20 μM Compound: 5-Fu	Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay	[PMID: 22512908]
OVCAR-5	GI₅₀	26.4 nM Compound: 5FU	Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay	[PMID: 23094992]
OVCAR-8	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
OVCAR-8	GI₅₀	1.74 μM Compound: 5-FU	Anticancer activity against human OVCAR-8 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-8 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-8	GI₅₀	1.74 μM Compound: 5-FU	Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-8	IC₅₀	96.37 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay	[PMID: 18469809]
P388	IC₅₀	0.0219 mM Compound: 5-FU	Cytotoxicity against Mus musculus (mouse) P388 cells assessed as growth inhibition after 72 hr by MTT assay Cytotoxicity against Mus musculus (mouse) P388 cells assessed as growth inhibition after 72 hr by MTT assay	10.1007/s00044-012-0181-0
P388	IC₅₀	1.7 pM Compound: 5-FU	Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay	[PMID: 21640594]
P388	IC₅₀	5.8 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
P388	ED₅₀	6.2 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse P388 cells by Alamar blue assay Cytotoxicity against mouse P388 cells by Alamar blue assay	[PMID: 24128077]
P388	IC₅₀	609 nM Compound: Fluorouracil	Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay	[PMID: 2778449]
PA-1	IC₅₀	39.5 μM Compound: 5-FU	Growth inhibition of human PA1 cells after 24 hrs by MTT assay Growth inhibition of human PA1 cells after 24 hrs by MTT assay	[PMID: 28011220]
PA-1	IC₅₀	39.5 μM Compound: 5-FU	Cytotoxicity against human PA1 cells after 24 hrs by MTT assay Cytotoxicity against human PA1 cells after 24 hrs by MTT assay	[PMID: 23202484]
PA-1	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test	[PMID: 21530016]
PA-1	IC₅₀	7.59 μM Compound: 5-FU	Anticancer activity against human PA1 cells after 48 hrs by MTT assay Anticancer activity against human PA1 cells after 48 hrs by MTT assay	[PMID: 26413726]
PA-1	IC₅₀	8.51 μM Compound: F	Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
PANC-1	IC₅₀	0.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
PANC-1	IC₅₀	100 μM Compound: 5-Fluorouracil	Cytotoxicity against human PANC-1 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human PANC-1 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
PANC-1	IC₅₀	15 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
PANC-1	IC₅₀	3.7 μM Compound: 5-fluorouracil	Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay	[PMID: 25919052]
PANC-1	IC₅₀	3.94 μM Compound: 5-FU	Cytotoxicity against human PANC1 cells by crystal violet staining Cytotoxicity against human PANC1 cells by crystal violet staining	[PMID: 20930123]
PANC-1	IC₅₀	4.3 μM Compound: 5-fluorouracil	Antiproliferative activity against human Panc-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay Antiproliferative activity against human Panc-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay	[PMID: 32007666]
PANC-1	IC₅₀	47.83 μM Compound: 5-Fu	Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay	[PMID: 28110871]
PANC-1	IC₅₀	50 μM Compound: 5-FU	Cytotoxicity against human PANC1 cells assessed as inhibition of cell viability after 6 days by MTT assay Cytotoxicity against human PANC1 cells assessed as inhibition of cell viability after 6 days by MTT assay	[PMID: 23360104]
PANC-1	IC₅₀	50 μM Compound: 5-FU	Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay	[PMID: 25124114]
PANC-1	IC₅₀	54.1 μM Compound: 5-fluorouracil	Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
PANC-1	IC₅₀	62.303 μM Compound: 5-Fluorouracil	Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
Panel NCI-60 cells	GI₅₀	18000 μM Compound: 5-fluorouracil	Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) incubated for 48 hrs by sulforhodamine B assay Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) incubated for 48 hrs by sulforhodamine B assay	[PMID: 33766762]
Panel NCI-60 cells	GI₅₀	22.6 μM Compound: 5-Fluorouracil	Anticancer activity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B assay Anticancer activity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B assay	[PMID: 31881454]
PaTu 8988t	IC₅₀	2.08 μM Compound: 5-FU	Cytotoxicity against human Patu-T cells by crystal violet staining Cytotoxicity against human Patu-T cells by crystal violet staining	[PMID: 20930123]
PaTu 8988t	IC₅₀	33.2 μM Compound: 5-FU	Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining	[PMID: 20930123]
PBMC	IC₅₀	> 40 μM Compound: 5-Fu	Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
PBMC	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human PBMC cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human PBMC cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 31877536]
PBMC	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
PC-3	IC₅₀	> 30 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 29133061]
PC-3	IC₅₀	0.016 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 19423198]
PC-3	IC₅₀	0.03 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay	[PMID: 27156770]
PC-3	IC₅₀	0.53 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29254641]
PC-3	IC₅₀	1.2 mM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27847140]
PC-3	IC₅₀	1.2 μM Compound: 5-FU	Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay	[PMID: 28923381]
PC-3	IC₅₀	1.2 μM Compound: 5-FU	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 28431881]
PC-3	IC₅₀	1.44 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26735909]
PC-3	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
PC-3	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
PC-3	IC₅₀	10.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human PC-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
PC-3	IC₅₀	10.4 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34455358]
PC-3	GI₅₀	10.45 nM Compound: 5FU	Growth inhibition of human PC3 cells after 48 hrs by SRB assay Growth inhibition of human PC3 cells after 48 hrs by SRB assay	[PMID: 23094992]
PC-3	IC₅₀	106.26 μM Compound: 2; 5-FU	Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay	[PMID: 27322756]
PC-3	GI₅₀	11.7 μM Compound: 5-Fluorouracil	Growth inhibition of human PC3 cells after 48 hrs by SRB assay Growth inhibition of human PC3 cells after 48 hrs by SRB assay	[PMID: 28898082]
PC-3	IC₅₀	12 μM Compound: 5-fluorouracil	Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
PC-3	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity against prostate cancer PC-3 cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer PC-3 cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
PC-3	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 24956552]
PC-3	GI₅₀	12 μM Compound: 5FU	Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
PC-3	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer PC-3 cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer PC-3 cell line by sulforhodamine B assay	[PMID: 16005217]
PC-3	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate PC-3 cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate PC-3 cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
PC-3	IC₅₀	12.23 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
PC-3	IC₅₀	12.33 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29635165]
PC-3	IC₅₀	12.87 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 28763643]
PC-3	IC₅₀	13.3 μM Compound: 5 Fluorouracil	Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
PC-3	IC₅₀	13.7 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
PC-3	IC₅₀	13.77 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
PC-3	GI₅₀	14.6 μM Compound: 5FU	Cytotoxicity against human PC3 cells after 48 hrs Cytotoxicity against human PC3 cells after 48 hrs	[PMID: 18798609]
PC-3	IC₅₀	15.12 μM Compound: 5-Fu	Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36216031]
PC-3	IC₅₀	15.31 μM Compound: 5-Fu	Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 28011223]
PC-3	IC₅₀	15.69 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC3 after 48 hrs by MTT assay Cytotoxicity against human PC3 after 48 hrs by MTT assay	[PMID: 21486698]
PC-3	IC₅₀	17.31 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells measured after 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells measured after 48 hrs by MTT assay	[PMID: 32135407]
PC-3	IC₅₀	18.4 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32682200]
PC-3	IC₅₀	18.42 μM Compound: 5-FU	Anticancer activity against human PC-3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human PC-3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
PC-3	IC₅₀	19.87 μM Compound: 5-fluorouracil	Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
PC-3	IC₅₀	2.1 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 22424614]
PC-3	IC₅₀	2.2 μM Compound: 5-FU	Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 24910974]
PC-3	IC₅₀	2.2 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
PC-3	IC₅₀	2.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 26222449]
PC-3	GI₅₀	2.36 μM Compound: 5-FU	Anticancer activity against human PC-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human PC-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
PC-3	GI₅₀	2.36 μM Compound: 5-FU	Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
PC-3	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
PC-3	IC₅₀	2.48 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 20800480]
PC-3	IC₅₀	2.5 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
PC-3	IC₅₀	2.76 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 27092413]
PC-3	IC₅₀	2.88 μM Compound: 5-fluoro uracil	Cytotoxicity against human PC-3 cells incubated for 3 days by MTT assay Cytotoxicity against human PC-3 cells incubated for 3 days by MTT assay	[PMID: 33152379]
PC-3	IC₅₀	20.42 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 31740251]
PC-3	IC₅₀	20.45 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
PC-3	GI₅₀	21 μM Compound: 5-Fu	Growth inhibition of human PC3 cells after 48 hrs by SRB assay Growth inhibition of human PC3 cells after 48 hrs by SRB assay	[PMID: 22512908]
PC-3	IC₅₀	22.02 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells by MTT assay Antiproliferative activity against human PC3 cells by MTT assay	[PMID: 29131616]
PC-3	IC₅₀	22.63 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 26363869]
PC-3	IC₅₀	23.1 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 30527868]
PC-3	IC₅₀	23.86 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29524728]
PC-3	IC₅₀	23.86 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29407983]
PC-3	IC₅₀	23.94 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
PC-3	IC₅₀	24.3 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 28494251]
PC-3	IC₅₀	24.33 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 28458133]
PC-3	IC₅₀	24.76 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
PC-3	IC₅₀	24.76 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 23792764]
PC-3	IC₅₀	27.07 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay	[PMID: 23735281]
PC-3	IC₅₀	27.07 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
PC-3	IC₅₀	27.61 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29407946]
PC-3	IC₅₀	27.64 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
PC-3	IC₅₀	29.3 μM Compound: 5-Fu	Antitumor activity against human PC3 cells after 72 hrs by MTT assay Antitumor activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21486694]
PC-3	IC₅₀	29.31 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 28038329]
PC-3	IC₅₀	30 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
PC-3	IC₅₀	31.44 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay	[PMID: 23735281]
PC-3	IC₅₀	32.87 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability by MTT assay	[PMID: 34715305]
PC-3	IC₅₀	35.75 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells by MTT assay Cytotoxicity against human PC3 cells by MTT assay	[PMID: 22801644]
PC-3	IC₅₀	38.61 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
PC-3	GI₅₀	4.1 μM Compound: 5-FU	Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay	[PMID: 27504537]
PC-3	IC₅₀	4.68 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 24798098]
PC-3	IC₅₀	4.75 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 29133051]
PC-3	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
PC-3	IC₅₀	42.5 μM Compound: 5-FU	Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay	[PMID: 27537924]
PC-3	IC₅₀	42.5 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 26595184]
PC-3	IC₅₀	45.32 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
PC-3	IC₅₀	46 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
PC-3	IC₅₀	49.1 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 30737134]
PC-3	IC₅₀	5.32 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
PC-3	IC₅₀	57.04 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay	[PMID: 27287368]
PC-3	IC₅₀	6.23 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
PC-3	IC₅₀	6.27 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29475156]
PC-3	IC₅₀	6.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 24 hrs Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 24 hrs	[PMID: 31945642]
PC-3	IC₅₀	63.8 μM Compound: 5-fluorouracil	Cytotoxicity against human PC3 cells after 24 hrs by MTT assay Cytotoxicity against human PC3 cells after 24 hrs by MTT assay	[PMID: 31401008]
PC-3	IC₅₀	68.28 μM Compound: 5-FU	Anticancer activity against human PC3 cells after 48 hrs by MTT assay Anticancer activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 26413726]
PC-3	IC₅₀	72.07 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
PC-3	IC₅₀	8.41 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
PC-3	IC₅₀	8.45 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 29958763]
PC-3	IC₅₀	9.09 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
PC-3	IC₅₀	9.5 μM Compound: 5-fluorouracil	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
PC-3M	IC₅₀	22.63 μM Compound: Fluorouracil	Cytotoxicity against human PC3M cells after 48 hrs by MTT assay Cytotoxicity against human PC3M cells after 48 hrs by MTT assay	[PMID: 22809558]
PC-9	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human PC-9 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human PC-9 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
PC-9	IC₅₀	1.99 μM Compound: 5-FU	Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
PC-9	IC₅₀	23.47 μM Compound: 5-FU	Cytotoxicity against human PC9 cells after 48 hrs by MTT assay Cytotoxicity against human PC9 cells after 48 hrs by MTT assay	[PMID: 22483608]
PC-9	IC₅₀	3.25 μM Compound: 5-Fu	Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
PC-9	IC₅₀	4.12 μM Compound: 5-Fu	Antiproliferative activity against human PC9 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human PC9 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
PC-9	IC₅₀	6.52 μM Compound: 5-Fu	Antiproliferative activity against human PC-9 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human PC-9 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
PLC	IC₅₀	116.8 μM Compound: 5-Fu	Antiproliferative activity against human PLC cells after 48 hrs by MTT assay Antiproliferative activity against human PLC cells after 48 hrs by MTT assay	[PMID: 30737134]
PLC-PRF-5	IC₅₀	2.8 μM Compound: Fluorouracil	Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
PLC-PRF-5	IC₅₀	22.81 μM Compound: 2; 5-FU	Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
PLC-PRF-5	IC₅₀	35.66 μM Compound: 2; 5-FU	Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay	[PMID: 29202398]
PLC-PRF-5	IC₅₀	38.35 μM Compound: 2; 5-FU	Antiproliferative activity against human PLC-PRF-5 cells after 48 hrs by MTT assay Antiproliferative activity against human PLC-PRF-5 cells after 48 hrs by MTT assay	[PMID: 27322756]
PPC-1	IC₅₀	6.4 μM Compound: 5-FU	Antiproliferative activity against prostate cancer PPC-1 cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer PPC-1 cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
PPC-1	IC₅₀	6.4 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer PPC-1 cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer PPC-1 cell line by sulforhodamine B assay	[PMID: 16005217]
PSN1	IC₅₀	4.4 μM Compound: 5-fluorouracil	Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay	[PMID: 25919052]
PSN1	IC₅₀	8.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
QGY-7703	IC₅₀	14.2 μM Compound: 5-Fu	Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay	[PMID: 29499490]
QGY-7703	IC₅₀	15.66 μM Compound: 5-Fu	Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay	[PMID: 24013415]
RKO	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human RKO cells after 24 hrs by MTT assay Cytotoxicity against human RKO cells after 24 hrs by MTT assay	[PMID: 32223193]
RKO	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell growth after 24 hrs by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell growth after 24 hrs by MTT assay	[PMID: 26922233]
RKO	IC₅₀	10.09 μM Compound: 5-FU	Antitumor activity against human RKO cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human RKO cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
RKO	IC₅₀	10.2 μM Compound: 5-FU	Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay	[PMID: 30106289]
RKO	IC₅₀	12.71 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
RKO	IC₅₀	2.9 μM Compound: 5-FU	Antiproliferative activity against human RKO cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human RKO cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
RKO	IC₅₀	4.39 μM Compound: 5-Fu	Cytotoxicity against human RKO cells after 3 days by SRB assay Cytotoxicity against human RKO cells after 3 days by SRB assay	[PMID: 24704691]
RKO	IC₅₀	41.1 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26922233]
RKO	IC₅₀	6.8 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 26922233]
RL	IC₅₀	3.2 μM Compound: 5-FU	Antiproliferative activity against human RL cells after 72 hrs by MTT assay Antiproliferative activity against human RL cells after 72 hrs by MTT assay	[PMID: 19743863]
RPMI-8226	GI₅₀	0.04 μM Compound: 5-FU	Anticancer activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
RPMI-8226	GI₅₀	0.04 μM Compound: 5-FU	Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
RPMI-8226	IC₅₀	3.55 μM Compound: 5-Fluorouracil	Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
RXF 393	GI₅₀	2.61 μM Compound: 5-FU	Anticancer activity against human RXF 393 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human RXF 393 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
RXF 393	GI₅₀	2.61 μM Compound: 5-FU	Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
RXF 393	IC₅₀	28.23 μM Compound: 5-FU	Cytotoxicity against human RXF 393 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay Cytotoxicity against human RXF 393 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay	[PMID: 35182815]
SCC-9	IC₅₀	12.7 μg/mL Compound: 5-FU	Antiproliferative activity against human SCC-9 cells assessed as cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human SCC-9 cells assessed as cell viability measured after 72 hrs by MTT assay	[PMID: 34463097]
SF-268	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
SF-268	GI₅₀	1.62 μM Compound: 5-FU	Anticancer activity against human SF-268 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SF-268 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SF-268	GI₅₀	1.62 μM Compound: 5-FU	Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SF-268	GI₅₀	49.21 μM Compound: 5-FU	Cytotoxicity against human SF268 cells after 48 hrs by SRB assay Cytotoxicity against human SF268 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
SF-268	IC₅₀	87.96 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs	[PMID: 18469809]
SF-295	GI₅₀	0.22 μM Compound: 5-FU	Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SF-295	GI₅₀	76 μM Compound: 5-Fu	Growth inhibition of human SF295 cells after 48 hrs by SRB assay Growth inhibition of human SF295 cells after 48 hrs by SRB assay	[PMID: 22512908]
SF-539	GI₅₀	0.06 μM Compound: 5-FU	Anticancer activity against human SF-539 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SF-539 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SF-539	GI₅₀	0.06 μM Compound: 5-FU	Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SF-539	IC₅₀	43 μM Compound: 5-FU	Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
SF-539	IC₅₀	50.09 μM Compound: 5-FU	Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
SGC-7901	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
SGC-7901	IC₅₀	0.58 μg/mL Compound: 5-FU	Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay	10.1007/s00044-009-9193-9
SGC-7901	IC₅₀	0.86 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
SGC-7901	IC₅₀	10.98 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 29133051]
SGC-7901	IC₅₀	11.9 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay	[PMID: 27537924]
SGC-7901	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 26595184]
SGC-7901	IC₅₀	11.96 μM Compound: 5-FU	Cytotoxicity against human SGC7901 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human SGC7901 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
SGC-7901	IC₅₀	12 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 6 days by MTT assay Cytotoxicity against human SGC7901 cells after 6 days by MTT assay	[PMID: 29786436]
SGC-7901	IC₅₀	13.25 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
SGC-7901	IC₅₀	14.49 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 22687745]
SGC-7901	IC₅₀	16.03 μg/mL Compound: 5-fluorouracil	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 28988624]
SGC-7901	IC₅₀	19.84 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 29635169]
SGC-7901	IC₅₀	2.19 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay	10.1007/s00044-010-9395-1
SGC-7901	IC₅₀	2.95 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 20494492]
SGC-7901	IC₅₀	2.96 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells incubated for 72 hrs by MTT assay	[PMID: 31404863]
SGC-7901	IC₅₀	21 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability by MTT assay	[PMID: 31029946]
SGC-7901	IC₅₀	28.5 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 23279864]
SGC-7901	IC₅₀	28.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 23490159]
SGC-7901	IC₅₀	29.19 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay	10.1007/s00044-011-9549-9
SGC-7901	IC₅₀	31.46 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 after 48 hrs by MTT assay Cytotoxicity against human SGC7901 after 48 hrs by MTT assay	[PMID: 21486698]
SGC-7901	IC₅₀	34.4 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 29232583]
SGC-7901	IC₅₀	36.4 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 30108895]
SGC-7901	IC₅₀	46.35 μM Compound: 5-Fluorouracil	Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay	[PMID: 23312949]
SGC-7901	IC₅₀	5.54 μM Compound: 5-FU	Anticancer activity against human SGC-7901 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human SGC-7901 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
SGC-7901	IC₅₀	53.58 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 30826506]
SGC-7901	IC₅₀	53.58 μM Compound: 5-FU	Cytotoxicity against human SGC-7901 cells by MTT assay Cytotoxicity against human SGC-7901 cells by MTT assay	[PMID: 33831559]
SGC-7901	IC₅₀	56.12 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 27503679]
SGC-7901	IC₅₀	59.9 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 25164762]
SGC-7901	IC₅₀	6.04 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 23920246]
SGC-7901	IC₅₀	6.04 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay	[PMID: 22579780]
SGC-7901	IC₅₀	6.12 μM Compound: 5-Fluorouracil	Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
SGC-7901	IC₅₀	6.3 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 22727445]
SGC-7901	IC₅₀	6.38 μM Compound: 5-Fu	Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
SGC-7901	IC₅₀	6.46 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
SGC-7901	IC₅₀	6.56 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 25554922]
SGC-7901	IC₅₀	6.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability measured for 24 hrs Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability measured for 24 hrs	[PMID: 31945642]
SGC-7901	IC₅₀	69.81 μM Compound: 5-Fu	Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
SGC-7901	EC₅₀	7.03 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 26883149]
SGC-7901	IC₅₀	7.11 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 22405648]
SGC-7901	IC₅₀	7.36 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 20947362]
SGC-7901	IC₅₀	7.37 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 24119869]
SGC-7901	IC₅₀	7.38 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 20800480]
SGC-7901	IC₅₀	7.38 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 after 48 hrs by MTT assay Cytotoxicity against human SGC7901 after 48 hrs by MTT assay	[PMID: 20538457]
SGC-7901	IC₅₀	76 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 2 days by alamar blue assay Cytotoxicity against human SGC7901 cells after 2 days by alamar blue assay	[PMID: 22093761]
SGC-7901	IC₅₀	8.7 μg/mL Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 22647218]
SH-SY5Y	IC₅₀	0.97 μM Compound: 5-Fu	Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 23685571]
SH-SY5Y	IC₅₀	1.09 μM Compound: 5-Fu	Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 22687745]
SH-SY5Y	GI₅₀	1.5 μM Compound: 5-FU	Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control	[PMID: 26539626]
SH-SY5Y	GI₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay	[PMID: 29040954]
SH-SY5Y	GI₅₀	12 μM Compound: 5-Fu	Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay	[PMID: 28763647]
SH-SY5Y	IC₅₀	3.26 μM Compound: 5-Fu	Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
SiHa	IC₅₀	218 μM Compound: 5-Fu	Cytotoxicity against human SiHa cells after 48 hrs by MTT assay Cytotoxicity against human SiHa cells after 48 hrs by MTT assay	[PMID: 22244588]
SiHa	GI₅₀	6.3 μM Compound: 5FU	Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
SK-BR-3	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
SK-BR-3	IC₅₀	> 20 μM Compound: 5-fluorouracil	Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
SK-BR-3	GI₅₀	3 μM Compound: 5-fluorouracil	Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay	[PMID: 20438092]
SK-BR-3	IC₅₀	38.25 μM Compound: 5-FU	Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay	[PMID: 21524829]
SK-BR-3	IC₅₀	38.88 μM Compound: 5-FU	Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay	[PMID: 25466196]
SK-HEP1	IC₅₀	12.5 μM Compound: 5-FU	Anticancer activity against human SK-HEP1 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human SK-HEP1 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
SK-HEP1	IC₅₀	4.95 μM Compound: 5-Fu	Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
SK-HEP1	GI₅₀	6.3 μM Compound: 5-Fu	Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay	[PMID: 22512908]
SK-HEP1	GI₅₀	7.6 nM Compound: 5FU	Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay	[PMID: 23094992]
SK-MEL	IC₅₀	6.3 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human SK-MEL cells after 2 to 7 days by neutral red assay Cytotoxicity against human SK-MEL cells after 2 to 7 days by neutral red assay	[PMID: 11374943]
SK-MEL-2	GI₅₀	56.7 μM Compound: 5-FU	Anticancer activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-MEL-2	GI₅₀	56.7 μM Compound: 5-FU	Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-MEL-2	IC₅₀	6.52 μM Compound: 5-Fu	Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
SK-MEL-28	GI₅₀	1.03 μM Compound: 5-FU	Anticancer activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-MEL-28	GI₅₀	1.03 μM Compound: 5-FU	Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-MEL-28	IC₅₀	11 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human melanoma cell line P36 after 72 hr of incubation The compound was evaluated for antitumoral activity against human melanoma cell line P36 after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
SK-MEL-28	IC₅₀	14.64 μM Compound: 5-FU	Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
SK-MEL-5	GI₅₀	0.46 μM Compound: 5-FU	Anticancer activity against human SK-MEL-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-MEL-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-MEL-5	GI₅₀	0.46 μM Compound: 5-FU	Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-MEL-5	IC₅₀	15.31 μM Compound: 5-FU	Cytotoxicity against human SK-MEL-5 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay Cytotoxicity against human SK-MEL-5 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay	[PMID: 35182815]
SK-N-SH	IC₅₀	10.32 μM Compound: 5-Fu	Antiproliferative activity against human SK-N-SH cells after 72 hrs by MTT assay Antiproliferative activity against human SK-N-SH cells after 72 hrs by MTT assay	10.1039/C6MD00169F
SK-N-SH	IC₅₀	7.22 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SK-N-SH cells by MTT assay Antiproliferative activity against human SK-N-SH cells by MTT assay	[PMID: 31546197]
SK-N-SH	IC₅₀	9.84 μM Compound: 5-FU	Cytotoxicity against human SK-N-SH cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human SK-N-SH cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27423479]
SK-OV-3	IC₅₀	> 10 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human SKOV3 cells after 2 to 7 days by neutral red assay Cytotoxicity against human SKOV3 cells after 2 to 7 days by neutral red assay	[PMID: 11374943]
SK-OV-3	IC₅₀	20.8 μM Compound: 5-Fu	Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
SK-OV-3	IC₅₀	21.6 μM Compound: 5-Fu	Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
SK-OV-3	GI₅₀	21.8 μM Compound: 5-FU	Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-OV-3	GI₅₀	21.8 μM Compound: 5-FU	Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-OV-3	IC₅₀	22.43 μM Compound: 5-FU	Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
SK-OV-3	IC₅₀	23.11 μM Compound: 5-Fu	Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 28011223]
SK-OV-3	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 3 days by MTT assay Cytotoxicity against human SKOV3 cells after 3 days by MTT assay	[PMID: 24095745]
SK-OV-3	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 24565905]
SK-OV-3	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 23988357]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 30108826]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 30092368]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Antiproliferative activity against human SK-OV-3 cells by MTT assay Antiproliferative activity against human SK-OV-3 cells by MTT assay	[PMID: 33109400]
SK-OV-3	IC₅₀	27.34 μM Compound: 5-Fu	Cytotoxicity against human SKOV3 cells after 2 days by MTT assay Cytotoxicity against human SKOV3 cells after 2 days by MTT assay	[PMID: 25841196]
SK-OV-3	IC₅₀	32.5 μM Compound: 5-FU	Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 28756264]
SK-OV-3	IC₅₀	47.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human SK-OV-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human SK-OV-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
SMMC-7721	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 22537362]
SMMC-7721	IC₅₀	12.47 μM Compound: 5-Fu	Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay	[PMID: 29499490]
SMMC-7721	IC₅₀	13.7 μM Compound: 5-Fu	Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 29475156]
SMMC-7721	IC₅₀	14.2 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
SMMC-7721	IC₅₀	14.55 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay	[PMID: 24013415]
SMMC-7721	IC₅₀	15.32 μM Compound: 5-FU	Antiproliferative activity against human SMMC-7721 cells by MTT assay Antiproliferative activity against human SMMC-7721 cells by MTT assay	[PMID: 33109400]
SMMC-7721	IC₅₀	19.25 μg/mL Compound: 5-fluorouracil	Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 28988624]
SMMC-7721	IC₅₀	2.3 x 10^-2 μg/mL Compound: fluorouracil	Cytotoxicity against human SMMC7721 cells by MTT assay Cytotoxicity against human SMMC7721 cells by MTT assay	[PMID: 22011319]
SMMC-7721	IC₅₀	2.5 μM Compound: Fluorouracil	Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
SMMC-7721	IC₅₀	20 μM Compound: 5-FU	Antiproliferative activity against human SMMC-7721 cells measured after 48 hrs Antiproliferative activity against human SMMC-7721 cells measured after 48 hrs	[PMID: 34128674]
SMMC-7721	IC₅₀	20.4 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 25707012]
SMMC-7721	IC₅₀	26.71 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 23644193]
SMMC-7721	IC₅₀	37.8 μM Compound: 5-FU	Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30739827]
SMMC-7721	IC₅₀	37.8 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 29232583]
SMMC-7721	IC₅₀	4.87 μM Compound: 5-Fluorouracil	Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
SMMC-7721	IC₅₀	5.62 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK-8 assay	[PMID: 27542307]
SMMC-7721	IC₅₀	5.62 μM Compound: 5-Fu	Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay	[PMID: 26786698]
SMMC-7721	IC₅₀	5.62 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay	[PMID: 25442303]
SMMC-7721	IC₅₀	51 μM Compound: 5-FU	Cytotoxicity against SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against SMMC7721 cells after 48 hrs by MTT assay	[PMID: 17604394]
SMMC-7721	IC₅₀	67.7 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 25164762]
SMMC-7721	IC₅₀	9.78 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
SMMC-7721	IC₅₀	9.78 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 23792764]
SN12C	GI₅₀	0.49 μM Compound: 5-FU	Anticancer activity against human SN12C cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SN12C cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SN12C	GI₅₀	0.49 μM Compound: 5-FU	Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SN12C	IC₅₀	6.5 μg/mL Compound: 5-Fu	Cytotoxicity against human SN12C cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human SN12C cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
SNB-19	GI₅₀	3.81 μM Compound: 5-FU	Anticancer activity against human SNB-19 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SNB-19 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SNB-19	GI₅₀	3.81 μM Compound: 5-FU	Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SNB-75	GI₅₀	78.7 μM Compound: 5-FU	Anticancer activity against human SNB-75 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SNB-75 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SNB-75	GI₅₀	78.7 μM Compound: 5-FU	Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SNU-16	EC₅₀	6.4 μM Compound: 5FU	Cytotoxicity against human SNU-16 cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human SNU-16 cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
SR	GI₅₀	0.02 μM Compound: 5-FU	Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SR	GI₅₀	0.0238 μM Compound: 5-FU	Cytotoxicity against human SR cells after 48 hrs by SRB assay Cytotoxicity against human SR cells after 48 hrs by SRB assay	[PMID: 22305543]
SR	IC₅₀	60.3 μM Compound: 5-Fluorouracil	Antileukemic activity against human SR cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human SR cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
SW 1116	IC₅₀	18.52 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 28363444]
SW 1116	IC₅₀	2.41 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method	[PMID: 23018096]
SW 1116	EC₅₀	28.52 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 21889345]
SW 1116	IC₅₀	37 μM Compound: 5-fluorouracil	Cytotoxicity against SW1116 cells by MTT colometric method Cytotoxicity against SW1116 cells by MTT colometric method	[PMID: 17253861]
SW 1116	IC₅₀	5.26 μM Compound: 5-FU	Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 24286761]
SW 1116	IC₅₀	76.92 μM Compound: 5-fluorouracil	Cytotoxicity against human SW1116 cells by disk diffusion soft agar colony formation assay Cytotoxicity against human SW1116 cells by disk diffusion soft agar colony formation assay	[PMID: 31117520]
SW 1116	IC₅₀	95.17 μM Compound: 5-FU	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 21962523]
SW1573	GI₅₀	4.1 μM Compound: 5-FU	Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
SW1573	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1573 cells by MTT assay Antiproliferative activity against human SW1573 cells by MTT assay	[PMID: 31546197]
SW1573	GI₅₀	4.3 μM Compound: 5-FU	Antiproliferative activity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
SW1573	GI₅₀	4.3 μM Compound: 5-FU	Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay	[PMID: 28728108]
SW1573	GI₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
SW1990	IC₅₀	126.4 μM Compound: 5-Fu	Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay	[PMID: 26714048]
SW1990	IC₅₀	45 μM Compound: 5-fu	Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay	[PMID: 22304344]
SW48	IC₅₀	4.4 μM Compound: 5-FU	Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay	[PMID: 19743863]
SW48	IC₅₀	5.3 μM Compound: 5-FU	Antiproliferative activity against human SW48 cells after 72 hrs Antiproliferative activity against human SW48 cells after 72 hrs	[PMID: 17548198]
SW480	IC₅₀	> 30 μM Compound: 5-FU	Antitumor activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
SW480	IC₅₀	12.4 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
SW480	IC₅₀	13.1 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
SW480	IC₅₀	13.16 μM Compound: 5-FU	Cytotoxicity against human SW480 cells by MTT assay Cytotoxicity against human SW480 cells by MTT assay	[PMID: 18644718]
SW480	IC₅₀	15.3 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
SW480	IC₅₀	15.71 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 24 hrs by MTT assay Cytotoxicity against human SW480 cells after 24 hrs by MTT assay	[PMID: 22182926]
SW480	IC₅₀	15.71 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 23920246]
SW480	IC₅₀	15.71 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay	[PMID: 22579780]
SW480	IC₅₀	158.2 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 23356786]
SW480	IC₅₀	2.1 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay	[PMID: 19743863]
SW480	IC₅₀	21.93 μM Compound: 5-FU	Anticancer activity against human SW480 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human SW480 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
SW480	IC₅₀	26.26 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay	[PMID: 18469809]
SW480	ED₅₀	3.09 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human SW480 cells after 3 days by trypan blue exclusion technique Cytotoxicity against human SW480 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
SW480	IC₅₀	3.5 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells after 72 hrs Antiproliferative activity against human SW480 cells after 72 hrs	[PMID: 17548198]
SW480	IC₅₀	3.69 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 3 days by SRB assay Cytotoxicity against human SW480 cells after 3 days by SRB assay	[PMID: 24704691]
SW480	IC₅₀	32.72 μM Compound: 5-Fu	Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
SW480	IC₅₀	57 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
SW480	IC₅₀	6 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human cancer cell line SW480 after 72 hr of incubation The compound was evaluated for antitumoral activity against human cancer cell line SW480 after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
SW480	IC₅₀	8.1 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 72 hrs by MTT assay Cytotoxicity against human SW480 cells after 72 hrs by MTT assay	[PMID: 23792763]
SW480	IC₅₀	8.1 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells after 72 hrs by MTT method Antiproliferative activity against human SW480 cells after 72 hrs by MTT method	[PMID: 17524655]
SW480	IC₅₀	9.7 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
SW-620	IC₅₀	> 10 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
SW-620	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
SW-620	EC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 24 hrs by MTT assay Antiproliferative activity against human SW620 cells after 24 hrs by MTT assay	[PMID: 25198997]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 29133046]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 28525845]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 27875779]
SW-620	IC₅₀	0.79 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 26617970]
SW-620	IC₅₀	0.79 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
SW-620	GI₅₀	0.92 μM Compound: 5-FU	Anticancer activity against human SW-620 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SW-620 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SW-620	GI₅₀	0.92 μM Compound: 5-FU	Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SW-620	IC₅₀	10 μM Compound: 5-FU	Cytotoxicity against human SW620 cells after 24 hrs by MTT assay Cytotoxicity against human SW620 cells after 24 hrs by MTT assay	[PMID: 32223193]
SW-620	IC₅₀	13.25 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36269639]
SW-620	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
SW-620	IC₅₀	15.29 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW-620 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human SW-620 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
SW-620	IC₅₀	18.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
SW-620	IC₅₀	3.38 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 21524829]
SW-620	IC₅₀	5.3 μM Compound: 5-FU	Cytotoxicity against human SW620 cells after 72 hrs by MTS assay Cytotoxicity against human SW620 cells after 72 hrs by MTS assay	[PMID: 25066282]
SW-620	IC₅₀	6.68 μM Compound: 5-Fluoruracil	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 22555152]
SW-620	IC₅₀	6.96 μM Compound: 5-FU	Cytotoxicity against human SW-620 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SW-620 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32203786]
SW-620	IC₅₀	8.7 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 3 days by MTT assay Antiproliferative activity against human SW620 cells after 3 days by MTT assay	[PMID: 18424155]
SW-620	IC₅₀	9 μM Compound: 5-FU	Antitumor activity against human SW620 cells after 24 hrs by MTT assay Antitumor activity against human SW620 cells after 24 hrs by MTT assay	[PMID: 20211564]
SW-620	IC₅₀	9 μM Compound: 5-FU	Growth inhibition of human SW620 cells after 72 hrs by MTT assay Growth inhibition of human SW620 cells after 72 hrs by MTT assay	[PMID: 18640746]
SW620/5-FU	EC₅₀	> 1000 μM Compound: 5-FU	Antiproliferative activity against human SW620/5-FU cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human SW620/5-FU cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34688013]
SW620/5-FU	EC₅₀	> 1000 μM Compound: 5-FU	Reversal of 5-FU resistance against human SW620/5-FU cells assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay Reversal of 5-FU resistance against human SW620/5-FU cells assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay	[PMID: 34411894]
SW780	IC₅₀	6.99 μM Compound: 5-FU	Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
T-24	IC₅₀	12.89 μM Compound: 5-FU	Cytotoxicity against human T24 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human T24 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
T-24	IC₅₀	25.23 μM Compound: 5-FU	Antiproliferative activity against human T24 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human T24 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
T-24	IC₅₀	37.56 μM Compound: 5-FU	Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
T-24	IC₅₀	39.4 μM Compound: 5-Fu	Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
T-24	IC₅₀	40.14 μM Compound: 5-FU	Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 28754470]
T-24	IC₅₀	40.14 μM Compound: 5-FU	Antiproliferative activity against human T-24 cells by MTT assay Antiproliferative activity against human T-24 cells by MTT assay	[PMID: 33109400]
T-24	IC₅₀	40.57 μM Compound: 5-Fu	Cytotoxicity against human T24 cells after 2 days by MTT assay Cytotoxicity against human T24 cells after 2 days by MTT assay	[PMID: 25841196]
T-24	IC₅₀	6 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human cancer cell line T24 after 72 hr of incubation The compound was evaluated for antitumoral activity against human cancer cell line T24 after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
T47D	IC₅₀	0.6 μM Compound: 5-FU	Antiproliferative activity against human T47D cells after 72 hrs by MTT assay Antiproliferative activity against human T47D cells after 72 hrs by MTT assay	[PMID: 19743863]
T47D	IC₅₀	10.56 μM Compound: 5-Fu	Cytotoxicity against human T47D cells after 3 days by SRB assay Cytotoxicity against human T47D cells after 3 days by SRB assay	[PMID: 24704691]
T47D	IC₅₀	12.1 μM Compound: 5-FU	Antiproliferative activity against human T47D cells after 48 hrs by MTT assay Antiproliferative activity against human T47D cells after 48 hrs by MTT assay	[PMID: 28400238]
T47D	IC₅₀	171.06 μM Compound: Fluorouracil	Cytotoxicity against human T47D cells after 48 hrs by MTT assay Cytotoxicity against human T47D cells after 48 hrs by MTT assay	[PMID: 28789892]
T47D	GI₅₀	29 μM Compound: 5-FU	Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
T47D	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human T47D cells by MTT assay Antiproliferative activity against human T47D cells by MTT assay	[PMID: 31546197]
T47D	GI₅₀	47 μM Compound: 5-FU	Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
T47D	GI₅₀	47 μM Compound: 5-FU	Antiproliferative activity against human T47D cells after 48 hrs by SRB assay Antiproliferative activity against human T47D cells after 48 hrs by SRB assay	[PMID: 28728108]
T47D	GI₅₀	47 μM Compound: 5-fluorouracil	Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
T47D	GI₅₀	47 μM Compound: 5-Fluorouracil	Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
T47D	ED₅₀	50.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human T47D cells after 3 hrs by Alamar Blue assay Cytotoxicity against human T47D cells after 3 hrs by Alamar Blue assay	[PMID: 24020806]
T47D	IC₅₀	51.7 μM Compound: 5-FU	Growth inhibition of human T47D cells after 24 hrs by MTT assay Growth inhibition of human T47D cells after 24 hrs by MTT assay	[PMID: 28011220]
T47D	IC₅₀	51.8 μM Compound: 5-FU	Cytotoxicity against human T47D cells after 24 hrs by MTT assay Cytotoxicity against human T47D cells after 24 hrs by MTT assay	[PMID: 23202484]
T47D	IC₅₀	6.7 μM Compound: 5-FU	Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay	[PMID: 34847409]
T47D	IC₅₀	7.9 μM Compound: 5-FU	Cytotoxicity against human T47D cells after 72 hrs by SRB assay Cytotoxicity against human T47D cells after 72 hrs by SRB assay	[PMID: 25462277]
T47D	GI₅₀	8.12 μM Compound: 5-FU	Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
T47D	GI₅₀	8.12 μM Compound: 5-FU	Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
T47D	IC₅₀	8.91 μM Compound: 5FU	Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
T84	IC₅₀	> 10 μM Compound: 5-FU	Antiproliferative activity against human T84 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human T84 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
T84	IC₅₀	3.4 μM Compound: 5-Fu	Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay	[PMID: 30248657]
T84	IC₅₀	6.2 μM Compound: 5-FU	Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
TE-1	IC₅₀	16.53 μM Compound: 5-Fu	Cytotoxicity against human TE1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human TE1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
TE-1	IC₅₀	16.53 μM Compound: 5-Fu	Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay	[PMID: 29635165]
TE-1	IC₅₀	17.32 μM Compound: 5-FU	Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
THP-1	IC₅₀	0.01 μM Compound: 5-Fluorouracil	Cytotoxicity against human THP1 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay Cytotoxicity against human THP1 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay	10.1039/C5MD00289C
THP-1	IC₅₀	0.04 μM Compound: 5-Fluorouracil	Cytotoxicity against human THP1 cells after 48 hrs by SRB assay Cytotoxicity against human THP1 cells after 48 hrs by SRB assay	[PMID: 25259515]
THP-1	IC₅₀	0.54 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human THP1 cells after 24 hrs by MTT assay Cytotoxicity against human THP1 cells after 24 hrs by MTT assay	[PMID: 23352638]
THP-1	IC₅₀	1 μM Compound: 5-FU	Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
THP-1	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human THP1 cells after 48 hrs by MTT assay Cytotoxicity against human THP1 cells after 48 hrs by MTT assay	[PMID: 26854375]
THP-1	IC₅₀	4.87 μM Compound: 5-FU	Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
TIG-3	IC₅₀	8.4 μM Compound: 5-fluorouracil	Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay	[PMID: 25919052]
TK-10	GI₅₀	1.12 μM Compound: 5-FU	Anticancer activity against human TK-10 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human TK-10 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
TK-10	GI₅₀	1.12 μM Compound: 5-FU	Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
U-251	IC₅₀	0.54 μM Compound: 5-fluorouracil	Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay	[PMID: 30660827]
U-251	GI₅₀	0.9 μM Compound: 5-FU	Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
U-251	GI₅₀	0.92 μM Compound: 5-FU	Anticancer activity against human U-251 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human U-251 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
U-251	IC₅₀	24.69 μM Compound: 5-Fu	Cytotoxicity against human U251 cells after 48 hrs by MTT assay Cytotoxicity against human U251 cells after 48 hrs by MTT assay	[PMID: 27133593]
U-251	GI₅₀	30.1 μM Compound: 5-Fu	Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay	[PMID: 32832031]
U-251	IC₅₀	38.68 μM Compound: 5-Fu	Cytotoxicity against human U251 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human U251 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
U-251	IC₅₀	48.68 μM Compound: 5FU	Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
U-251	GI₅₀	69.6 nM Compound: 5FU	Growth inhibition of human U251 cells after 48 hrs by SRB assay Growth inhibition of human U251 cells after 48 hrs by SRB assay	[PMID: 23094992]
U-251	GI₅₀	82 μM Compound: 5-Fu	Growth inhibition of human U251 cells after 48 hrs by SRB assay Growth inhibition of human U251 cells after 48 hrs by SRB assay	[PMID: 22512908]
U-266	IC₅₀	43.48 μM Compound: 2; 5-FU	Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
U-266	IC₅₀	66.22 μM Compound: 2; 5-FU	Antiproliferative activity against human U266 cells after 48 hrs by MTT assay Antiproliferative activity against human U266 cells after 48 hrs by MTT assay	[PMID: 29202398]
U2OS	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
U2OS	IC₅₀	13.02 μM Compound: 5-Fu	Antiproliferative activity against human U2OS cells after 72 hrs by MTT assay Antiproliferative activity against human U2OS cells after 72 hrs by MTT assay	[PMID: 35609396]
U2OS	IC₅₀	13.18 μM Compound: 5-FU	Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
U2OS	IC₅₀	16 μM Compound: 5-FU	Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
U2OS	IC₅₀	7.2 μg/mL Compound: 5-FU	Cytotoxicity against human U2OS cells after 36 hrs by MTT assay Cytotoxicity against human U2OS cells after 36 hrs by MTT assay	[PMID: 20961091]
U-87MG ATCC	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
U-87MG ATCC	GI₅₀	13 μM Compound: 5-FU	Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 27688184]
U-87MG ATCC	IC₅₀	15.48 μM Compound: F	Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
U-87MG ATCC	IC₅₀	18.25 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method	[PMID: 27081742]
U-87MG ATCC	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
U-87MG ATCC	IC₅₀	219.6 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by Z2 coulter counter method Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by Z2 coulter counter method	[PMID: 27081742]
U-87MG ATCC	IC₅₀	22 μM Compound: 5-Fu	Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
U-87MG ATCC	IC₅₀	3.61 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26735909]
U-87MG ATCC	IC₅₀	3.65 μM Compound: 5-Fluorouracil	Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay	[PMID: 27092413]
U-87MG ATCC	IC₅₀	38.2 μM Compound: 5-Fu	Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
U-87MG ATCC	IC₅₀	45.3 μM Compound: 5-FU	Antiproliferative activity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30739827]
U-87MG ATCC	IC₅₀	49298 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by Z2 coulter counter method Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by Z2 coulter counter method	[PMID: 27081742]
U-87MG ATCC	IC₅₀	5.61 μM Compound: 5-Fu	Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
U-937	IC₅₀	0.87 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human U937 cells after 24 hrs by MTT assay Cytotoxicity against human U937 cells after 24 hrs by MTT assay	[PMID: 23352638]
U-937	IC₅₀	1.07 μM Compound: 5-FU	Cytotoxicity against human U937 cells after 72 hrs by MTT assay Cytotoxicity against human U937 cells after 72 hrs by MTT assay	[PMID: 22959518]
U-937	IC₅₀	23.93 μM Compound: 5-Fu	Growth inhibition against human U937 cells after 48 hrs by MTT assay Growth inhibition against human U937 cells after 48 hrs by MTT assay	[PMID: 23999046]
U-937	IC₅₀	23.93 μM Compound: 5-Fu	Cytotoxicity against human U937 cells after 48 hrs by MTT assay Cytotoxicity against human U937 cells after 48 hrs by MTT assay	[PMID: 23558238]
U-937	IC₅₀	28.76 μM Compound: 2; 5-FU	Antiproliferative activity against human U937 cells after 48 hrs by MTT assay Antiproliferative activity against human U937 cells after 48 hrs by MTT assay	[PMID: 29202398]
U-937	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) U937 cells after 96 hr by MTT assay Cytotoxicity against Homo sapiens (human) U937 cells after 96 hr by MTT assay	10.1007/s00044-011-9778-y
U-937	IC₅₀	56.28 μM Compound: 5-Fu	Antiproliferative activity against human U937 cells after 48 hrs by MTT assay Antiproliferative activity against human U937 cells after 48 hrs by MTT assay	[PMID: 29958763]
U-937	IC₅₀	9.56 μM Compound: 2; 5-FU	Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
UACC-257	GI₅₀	3.55 μM Compound: 5-FU	Anticancer activity against human UACC-257 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human UACC-257 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
UACC-257	GI₅₀	3.55 μM Compound: 5-FU	Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
UACC-62	GI₅₀	0.52 μM Compound: 5-FU	Anticancer activity against human UACC-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human UACC-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
UACC-62	GI₅₀	0.52 μM Compound: 5-FU	Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
UACC-62	IC₅₀	264 μM Compound: 5-Fluorouracil	Cytotoxicity against human UACC62 cells after 48 hrs by MTT assay Cytotoxicity against human UACC62 cells after 48 hrs by MTT assay	[PMID: 24177365]
UACC-812	IC₅₀	3.1 μM Compound: 5-FU	Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay	[PMID: 19743863]
UO-31	GI₅₀	1.42 μM Compound: 5-FU	Anticancer activity against human UO-31 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human UO-31 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
UO-31	GI₅₀	1.42 μM Compound: 5-FU	Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
Vero	IC₅₀	> 100 μM Compound: 5-Fu	Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay	[PMID: 22687745]
Vero	IC₅₀	0.05 mM Compound: 5-FU	Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
Vero	IC₅₀	4.5 μM Compound: 1, 5-FU	Growth inhibition of african green monkey Vero cells by crystal violet assay Growth inhibition of african green monkey Vero cells by crystal violet assay	[PMID: 23075414]
Vero	IC₅₀	6.4 μg/mL Compound: 5-FU	Cytotoxicity against African green monkey Vero cells after 96 hrs by MTT assay Cytotoxicity against African green monkey Vero cells after 96 hrs by MTT assay	[PMID: 23022735]
Vero	IC₅₀	6.5 μg/mL Compound: 5-Fu	Cytotoxicity against african green monkey Vero cells after 96 hrs by MTT assay Cytotoxicity against african green monkey Vero cells after 96 hrs by MTT assay	[PMID: 22204901]
Vero	IC₅₀	6.5 μg/mL Compound: 5-Fu	Cytotoxicity against african green monkey Vero cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against african green monkey Vero cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
Vero	IC₅₀	8 μM Compound: 5-FU	Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay	[PMID: 23800391]
Vero	IC₅₀	9.71 μM Compound: 5-Fu	Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay	[PMID: 23685571]
WI-38	IC₅₀	> 40 μM Compound: 5-Fu	Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
WI-38	IC₅₀	0.02 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) WI38 cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Homo sapiens (human) WI38 cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
WI-38	IC₅₀	0.051 mM Compound: 5-Fluorouracil	Cytotoxicity in human WI38 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human WI38 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
WI-38	IC₅₀	0.94 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 29133046]
WI-38	IC₅₀	0.94 μM Compound: 5-FU	Cytotoxicity against human WI38 cells after 72 hrs by MTT assay Cytotoxicity against human WI38 cells after 72 hrs by MTT assay	[PMID: 28525845]
WI-38	IC₅₀	0.94 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 27875779]
WI-38	IC₅₀	10 μM Compound: 5-FU	Cytotoxicity against human WI38 cells after 3 days by MTT assay Cytotoxicity against human WI38 cells after 3 days by MTT assay	[PMID: 18424155]
WI-38	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay	[PMID: 23800391]
WI-38	IC₅₀	18.5 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 21524829]
WI-38	IC₅₀	201.9 μM Compound: 5-FU	Cytotoxicity in human W138 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human W138 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
WI-38	IC₅₀	24.66 μM Compound: 5-Fluoruracil	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 22555152]
WI-38	IC₅₀	3.2 μg/mL Compound: 5-Fu	Cytotoxicity against human WI38 cells after 96 hrs by MTT assay Cytotoxicity against human WI38 cells after 96 hrs by MTT assay	[PMID: 22204901]
WI-38	IC₅₀	3.2 μg/mL Compound: 5-Fu	Cytotoxicity against human WI38 cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against human WI38 cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
WI-38	IC₅₀	38.91 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
WI-38	IC₅₀	4 μg/mL Compound: 5-FU	Cytotoxicity against human WI38 cells after 96 hrs by MTT assay Cytotoxicity against human WI38 cells after 96 hrs by MTT assay	[PMID: 23022735]
WI-38	IC₅₀	4 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27343853]
WI-38	IC₅₀	4.1 μM Compound: 5-Fu	Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31276896]
WI-38	IC₅₀	5.7 μM Compound: 5-Fluorouracil	Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
WI-38	IC₅₀	5.73 μM Compound: 5-Fluorouracil	Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
WI-38	IC₅₀	6.8 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
WI-38	IC₅₀	62 μM Compound: 5-Fluorouracil	Cytotoxicity against human WI-38 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human WI-38 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
WI-38	IC₅₀	78.5 μM Compound: 5-FU	Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 32485532]
WI-38	IC₅₀	8.4 μM Compound: 5-FU	Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 30856408]
WI-38	IC₅₀	9.3 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27951487]
WiDr	IC₅₀	10.5 μM Compound: 5-FU	Anticancer activity against human WiDr cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Anticancer activity against human WiDr cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34425478]
WiDr	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human WiDr cells by MTT assay Antiproliferative activity against human WiDr cells by MTT assay	[PMID: 31546197]
WiDr	GI₅₀	49 μM Compound: 5-FU	Antiproliferative activity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
WiDr	GI₅₀	49 μM Compound: 5-FU	Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay	[PMID: 28728108]
WiDr	GI₅₀	49 μM Compound: 5-Fluorouracil	Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
WiDr	GI₅₀	50 μM Compound: 5-FU	Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
WISH	IC₅₀	7.1 μM Compound: 5-FU	Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27951487]
WM 266-4	GI₅₀	28.76 μM Compound: 5-Fu	Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay	[PMID: 24934992]
ZR-75-1	GI₅₀	2.3 μM Compound: 5FU	Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]

体外研究
(In Vitro)

5-Fluorouracil (5-Fu) 和 NSC 123127 (Dox) 具有协同抗癌功效。5-Fu/Dox-DNM 对人乳腺癌 (MDA-MB-231) 细胞的 IC₅₀ 值为 0.25 μg/mL，细胞毒性分别增加 11.2 倍和 6.1 倍分别为 Dox-DNM 和 5-Fu-DNM^[1]。在 5-Fluorouracil (5-FU) 和 CDDP 处理的 NFBD1 抑制 NPC 细胞中，使用慢病毒介导的短发夹 RNA 耗尽 NPC CNE1 细胞系中的 NFBD1 表达，并且这些细胞的敏感性升高。NFBD1 敲低导致 CDDP 或 5-FU 处理的 CNE1 细胞明显诱导细胞凋亡^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

5-Fluorouracil (23 mg/kg，每周 3 次) 持续 14 天，在处理开始后第 3 天诱导与急性肠道炎症相关的胃肠道传输加速，这可能导致第 7 天后观察到的 ENS 持续变化和 14 项处理导致胃肠道传输延迟和结肠运动障碍^[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

130.08

Formula

C₄H₃FN₂O₂

CAS 号

51-21-8

性状

固体

颜色

White to off-white

中文名称

5-氟脲嘧啶；双喃呋啶

结构分类

Others

初始来源

内源性代谢物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

细胞实验：

DMSO 中的溶解度 : 50 mg/mL (384.38 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

1 M Ammonium hydroxide 中的溶解度 : 50 mg/mL (384.38 mM; 超声助溶)

H₂O 中的溶解度 : 10 mg/mL (76.88 mM; 超声助溶 (<60°C))

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	7.6876 mL	38.4379 mL	76.8758 mL
5 mM	1.5375 mL	7.6876 mL	15.3752 mL
10 mM	0.7688 mL	3.8438 mL	7.6876 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)

体积 _(start)

浓度 _(final)

体积 _(final)

动物实验：

请根据您的实验动物和给药方式选择适当的溶解方案。

以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；
以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

方案一

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (19.22 mM); 澄清溶液

此方案可获得 ≥ 2.5 mg/mL（饱和度未知）的澄清溶液。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；再向上述体系中加入 50 μL Tween-80，混合均匀；然后再继续加入 450 μL 生理盐水定容至 1 mL。
生理盐水的配制：将 0.9 g 氯化钠，溶解于 ddH₂O 并定容至 100 mL，可以得到澄清透明的生理盐水溶液。
方案二

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (19.22 mM); 澄清溶液

此方案可获得 ≥ 2.5 mg/mL（饱和度未知）的澄清溶液。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。
2 g SBE-β-CD（磺丁基醚 β-环糊精）粉末定容于 10 mL 的生理盐水中，完全溶解至澄清透明。
方案三

请依序添加每种溶剂： 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (19.22 mM); 澄清溶液

此方案可获得 ≥ 2.5 mg/mL（饱和度未知）的澄清溶液，此方案实验周期在半个月以上的动物实验酌情使用。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。
方案四

请依序添加每种溶剂： 5% DMSO 40% PEG300 5% Tween-80 50% Saline
Solubility: ≥ 2.5 mg/mL (19.22 mM); 澄清溶液
方案五

请依序添加每种溶剂： 5% DMSO 95% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (19.22 mM); 澄清溶液
方案六

请依序添加每种溶剂： 5% DMSO 95% Saline
Solubility: 2.5 mg/mL (19.22 mM); 澄清溶液; 超声助溶

以下溶解方案，请直接配制工作液。建议现用现配，在短期内尽快用完。以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

方案一

请依序添加每种溶剂： PBS
Solubility: 25 mg/mL (192.19 mM); 澄清溶液; 超声助溶

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

请输入您的动物体内配方组成：

DMSO +

Tween-80 +

Saline

如果您的动物是免疫缺陷鼠或者体弱鼠，建议 DMSO 中的在最后工作液体系中的占比尽量不超过 2%。

方案所需 助溶剂 包括：DMSO，，均可在 MCE 网站选购。，Tween 80，均可在 MCE 网站选购。

计算结果

工作液所需浓度 : mg/mL

储备液配制方法 : mg 药物溶于 μL DMSO（母液浓度为 mg/mL）。

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

您所需的储备液浓度超过该产品的实测溶解度，以下方案仅供参考，如有需要，请与 MCE 中国技术支持联系。

动物实验体内工作液的配制方法 : 取 μL DMSO 储备液，加入 μL 。 μL ，混合均匀至澄清，再加 μL Tween 80，混合均匀至澄清，再加 μL 生理盐水。

连续给药周期超过半月以上，请谨慎选择该方案。

请确保第一步储备液溶解至澄清状态，从左到右依次添加助溶剂。您可采用超声加热（超声清洗仪，建议频次 20-40 kHz），涡旋吹打等方式辅助溶解。

纯度 & 产品资料

纯度: 99.99%

选择批次：

Data Sheet (655 KB) SDS (584 KB)

COA (292 KB) RP-HPLC (258 KB) 元素分析报告 (216 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Han R, et al. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and NSC 123127 for enhanced therapeutic efficacy. J Drug Target. 2016 Jun 29:1-28. [Epub ahead of print] [Content Brief]

[2]. Zeng Q, et al. Knockdown of NFBD1/MDC1 enhances chemosensitivity to NSC 119875 or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells. Mol Cell Biochem. 2016 Jul;418(1-2):137-46. [Content Brief]

[3]. Jones DH, et al. Ten-Year and Beyond Follow-up After Treatment With Highly Purified Liquid-Injectable Silicone for HIV-Associated Facial Lipoatrophy: A Report of 164 Patients. Dermatol Surg. 2019 Jul;45(7):941-948. [Content Brief]

[4]. McQuade RM, et al. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anticancer chemotherapeutic agent 5-fluorouracil. Neurogastroenterol Motil. 2016 Jun 28. [Content Brief]

[5]. Yin L, et al. Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo. Ther Clin Risk Manag. 2017 Feb 7;13:117-130. [Content Brief]

[6]. Snyder SM, et al. Initial Experience with Topical Fluorouracil for Treatment of HIV-Associated Anal Intraepithelial Neoplasia. J Int Assoc Physicians AIDS Care (Chic). 2011;10(2):83-88. [Content Brief]

[7]. Pek Yee Lum, et al. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell. 2004 Jan 9;116(1):121-37. [Content Brief]

Animal Administration ^[2]	Mice receive intraperitoneal injections of 5-FU (23 mg/kg), 3 times a week via a 26 gauge needle. 5-FU is dissolved in 100% dimethyl sulfoxide (DMSO) to make 1 M/L stock solution refrigerated at −20°C. The stock is then defrosted and diluted with sterile water to make 0.1 M/L (10% DMSO) solutions for intraperitoneal injections. The dose of 5-FU is calculated to be equivalent to standard human dose per body surface area. The low doses of 5-FU (10-40 mg/kg) have been shown to have antitumor efficacy in mouse models of cancer. Sham-treated mice received 10% DMSO in sterile water via intraperitoneal injection three times a week via a 26 gauge needle. The injected volumes are calculated to the body weight; the maximum volume does not exceed 200 μL per injection. Mice are euthanized via cervical dislocation at 3 (2 treatments), 7 (3 treatments), and 14 (6 treatments) days after the first injection and colon is collected for in vitro experiments. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Han R, et al. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and NSC 123127 for enhanced therapeutic efficacy. J Drug Target. 2016 Jun 29:1-28. [Epub ahead of print] [Content Brief] [2]. Zeng Q, et al. Knockdown of NFBD1/MDC1 enhances chemosensitivity to NSC 119875 or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells. Mol Cell Biochem. 2016 Jul;418(1-2):137-46. [Content Brief] [3]. Jones DH, et al. Ten-Year and Beyond Follow-up After Treatment With Highly Purified Liquid-Injectable Silicone for HIV-Associated Facial Lipoatrophy: A Report of 164 Patients. Dermatol Surg. 2019 Jul;45(7):941-948. [Content Brief] [4]. McQuade RM, et al. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anticancer chemotherapeutic agent 5-fluorouracil. Neurogastroenterol Motil. 2016 Jun 28. [Content Brief] [5]. Yin L, et al. Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo. Ther Clin Risk Manag. 2017 Feb 7;13:117-130. [Content Brief] [6]. Snyder SM, et al. Initial Experience with Topical Fluorouracil for Treatment of HIV-Associated Anal Intraepithelial Neoplasia. J Int Assoc Physicians AIDS Care (Chic). 2011;10(2):83-88. [Content Brief] [7]. Pek Yee Lum, et al. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell. 2004 Jan 9;116(1):121-37. [Content Brief]

Animal Administration
^[2]

Mice receive intraperitoneal injections of 5-FU (23 mg/kg), 3 times a week via a 26 gauge needle. 5-FU is dissolved in 100% dimethyl sulfoxide (DMSO) to make 1 M/L stock solution refrigerated at −20°C. The stock is then defrosted and diluted with sterile water to make 0.1 M/L (10% DMSO) solutions for intraperitoneal injections. The dose of 5-FU is calculated to be equivalent to standard human dose per body surface area. The low doses of 5-FU (10-40 mg/kg) have been shown to have antitumor efficacy in mouse models of cancer. Sham-treated mice received 10% DMSO in sterile water via intraperitoneal injection three times a week via a 26 gauge needle. The injected volumes are calculated to the body weight; the maximum volume does not exceed 200 μL per injection. Mice are euthanized via cervical dislocation at 3 (2 treatments), 7 (3 treatments), and 14 (6 treatments) days after the first injection and colon is collected for in vitro experiments.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Han R, et al. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and NSC 123127 for enhanced therapeutic efficacy. J Drug Target. 2016 Jun 29:1-28. [Epub ahead of print] [Content Brief]

[2]. Zeng Q, et al. Knockdown of NFBD1/MDC1 enhances chemosensitivity to NSC 119875 or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells. Mol Cell Biochem. 2016 Jul;418(1-2):137-46. [Content Brief]

[3]. Jones DH, et al. Ten-Year and Beyond Follow-up After Treatment With Highly Purified Liquid-Injectable Silicone for HIV-Associated Facial Lipoatrophy: A Report of 164 Patients. Dermatol Surg. 2019 Jul;45(7):941-948. [Content Brief]

[4]. McQuade RM, et al. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anticancer chemotherapeutic agent 5-fluorouracil. Neurogastroenterol Motil. 2016 Jun 28. [Content Brief]

[5]. Yin L, et al. Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo. Ther Clin Risk Manag. 2017 Feb 7;13:117-130. [Content Brief]

[6]. Snyder SM, et al. Initial Experience with Topical Fluorouracil for Treatment of HIV-Associated Anal Intraepithelial Neoplasia. J Int Assoc Physicians AIDS Care (Chic). 2011;10(2):83-88. [Content Brief]

[7]. Pek Yee Lum, et al. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell. 2004 Jan 9;116(1):121-37. [Content Brief]

5-Fluorouracil 相关分类

完整储备液配制表

可选溶剂	浓度溶剂体积质量	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO / 1 M Ammonium hydroxide	1 mM	7.6876 mL	38.4379 mL	76.8758 mL	192.1894 mL
	5 mM	1.5375 mL	7.6876 mL	15.3752 mL	38.4379 mL
	10 mM	0.7688 mL	3.8438 mL	7.6876 mL	19.2189 mL
	15 mM	0.5125 mL	2.5625 mL	5.1251 mL	12.8126 mL
	20 mM	0.3844 mL	1.9219 mL	3.8438 mL	9.6095 mL
	25 mM	0.3075 mL	1.5375 mL	3.0750 mL	7.6876 mL
	30 mM	0.2563 mL	1.2813 mL	2.5625 mL	6.4063 mL
	40 mM	0.1922 mL	0.9609 mL	1.9219 mL	4.8047 mL
	50 mM	0.1538 mL	0.7688 mL	1.5375 mL	3.8438 mL
	60 mM	0.1281 mL	0.6406 mL	1.2813 mL	3.2032 mL
DMSO / 1 M Ammonium hydroxide	80 mM	0.0961 mL	0.4805 mL	0.9609 mL	2.4024 mL
DMSO / 1 M Ammonium hydroxide	100 mM	0.0769 mL	0.3844 mL	0.7688 mL	1.9219 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Fluorouracil51-21-85-FU5-氟脲嘧啶双喃呋啶Nucleoside Antimetabolite/AnalogHIVApoptosisEndogenous MetaboliteHuman immunodeficiency virusInhibitorinhibitorinhibit

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5-Fluorouracil (Synonyms: 5-氟脲嘧啶; 5-FU)

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5-Fluorouracil (Synonyms: 5-氟脲嘧啶; 5-FU)

Customer Review

Other Forms of 5-Fluorouracil:

5-Fluorouracil 相关抗体

MCE 顾客使用本产品发表的 203 篇科研文献

5-Fluorouracil 相关产品

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生物活性

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5-Fluorouracil 相关抗体:

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