2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Bethanechol

Bethanechol  (Synonyms: 贝胆碱; Carbamyl-β-methylcholine)

目录号: HY-B0406
产品使用指南

摩尔计算器

Bethanechol (Carbamyl-β-methylcholine) 是一种拟副交感神经剂。Bethanechol 是毒蕈碱型受体 (mAChR) 的激动剂，通过直接刺激副交感神经系统的 mAChR (M1、M2、M3、M4、M5) 发挥其作用。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Bethanechol chloride 通常具有更好的水溶性和稳定性。

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Bethanechol Chemical Structure

Bethanechol Chemical Structure

CAS No. : 674-38-4

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Bethanechol 的其他形式现货产品:

Other Forms of Bethanechol:

Bethanechol 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].

IC50 & Target

mAChR[1]
体外研究
(In Vitro)

Bethanechol (0.3-300 μM) significantly reduces ileal pacemaker potentials[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Bethanechol 相关抗体:
体内研究
(In Vivo)

Bethanechol (2-12 mg/kg; i.p.) induces drinking and increased urine output of rats in a dose-dependent fashion[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g) [4]
Dosage: 2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg
Administration: Intraperitoneal injection
Result: Increased water intake during the first hr in a dose-dependent fashion up to the highest dose administered (12 mg/kg).
Clinical Trial
分子量

161.22

Formula

C7H17N2O2
CAS 号
中文名称

贝胆碱
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Bethanechol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bethanechol674-38-4Carbamyl-β-methylcholine贝胆碱mAChRMuscarinic acetylcholine receptorparasympathomimeticparasympatheticreceptorspostoperativeurinaryretentionpostpartumurinary ,retentionoverflowincontinenceInhibitorinhibitorinhibit

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