1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-13
  5. IL-13 蛋白, Mouse

IL-13 蛋白, Mouse

目录号: HY-P70460
COA 产品使用指南

IL-13 蛋白, Mouse是一种免疫调节细胞因子,主要由活化的 Th2 细胞以及肥大细胞和 NK 细胞产生。 IL-13 对单核细胞和巨噬细胞发挥抗炎作用,并抑制炎症细胞因子如 IL-1β、TNF-α、IL-6 和 IL-8 的表达。

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规格 价格 是否有货 数量
Free Sample   Apply now  
2 μg ¥850 In-stock
10 μg ¥2200 In-stock
50 μg ¥6600 In-stock
100 μg ¥11200 询价
> 100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

  • 参考文献

描述

IL-13 Protein, Mouse is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8[1].

研究背景

IL-13 是体外巨噬细胞促炎活性的有效下调剂,与抗炎细胞因子 IL-4IL-10[1] 类似。

生物活性

The cell proliferation assay using TF-1 human erythroleukemic cells has an ED50 value of ≤1.876 ng/mL.

  • Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 1.876 ng/mL, corresponding to a specific activity is 5.330×105 U/mg.
种属

Mouse

表达系统

E. coli

标签

Tag Free

蛋白编号

P20109 (S26-F131)

基因 ID
蛋白结构
N-term
IL-13 (S26-F131)
Accession # P20109
C-term
同用名
Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13
氨基酸序列

SVSLPLTLKELIEELSNITQDQTPLCNGSMVWSVDLAAGGFCVALDSLTNISNCNAIYRTQRILHGLCNRKAPTTVSSLPDTKIEVAHFITKLLSYTKQLFRHGPF

分子量

Approximately 10.0 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of 20 mM Histidine-HCl, 8% Trehalose, 4% Mannitol, 50 mM NaCl, 0.05% Tween 80, pH 6.0 or PBS, pH 6.5, 8% trehalose.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
参考文献

IL-13 Protein, Mouse 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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