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  4. 蔗糖偏好实验 (SPT)
蔗糖偏好实验 (SPT)

蔗糖偏好实验(SPT,Sucrose Preference Test)是一种常用于评估小鼠或大鼠情感状态和愉悦程度的实验。在实验中,动物被提供两种饮水选择,一种是含蔗糖的水,另一种是普通的水。通过记录动物对含蔗糖水的摄取量,可以评估其对愉悦刺激的反应。减少对蔗糖水的偏好可能暗示着动物情感状态的改变,如抑郁。SPT 广泛用于研究抗抑郁药物效果、慢性压力模型和情感行为评估。


The sucrose preference test (SPT) is a test commonly used to evaluate the emotional state and pleasure of mice or rats. In the experiment, animals were provided with two drinking water options, one was water containing sucrose and the other was ordinary water. The animal's response to pleasurable stimuli can be assessed by recording its intake of sucrose-containing water. Reduced preference for sucrose water may suggest changes in the animal's emotional state, such as depression. SPT is widely used to study antidepressant drug effects, chronic stress models, and affective behavioral assessment.