2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Quetiapine sulfoxide

Quetiapine sulfoxide  (Synonyms: Quetiapine S-oxide)

目录号: HY-G0014
产品使用指南

摩尔计算器

Quetiapine sulfoxide (Quetiapine S-oxide) 是 Quetiapinem 的主要代谢产物。Quetiapinem 是第二代抗精神病药。Quetiapine 是一种 5-HT 受体激动剂，也是一种多巴胺受体 (dopamine receptor) 拮抗剂。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Quetiapine sulfoxide dihydrochloride 通常具有更好的水溶性和稳定性。

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Quetiapine sulfoxide Chemical Structure

Quetiapine sulfoxide Chemical Structure

CAS No. : 329216-63-9

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Quetiapine sulfoxide 的其他形式现货产品:

Other Forms of Quetiapine sulfoxide:

Quetiapine sulfoxide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2].

体内研究
(In Vivo)

The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng•h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

399.51

Formula

C21H25N3O3S
CAS 号
中文名称

喹硫平亚砜
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Quetiapine sulfoxide 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Quetiapine sulfoxide329216-63-9Quetiapine S-oxide喹硫平亚砜Drug MetaboliteInhibitorinhibitorinhibit

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