BTN3A1/CD277 蛋白, Human (HEK293)

BTN3A1/CD277 Protein, functioning as a homodimer, regulates activated T-cell proliferation, controls cytokine release, and mediates T-cell response to cells with elevated phosphorylated metabolites, such as isopentenyl pyrophosphate, contributing to T-cell activation and the adaptive immune response. BTN3A1/CD277 Protein, Human (HEK293) is the recombinant human-derived BTN3A1/CD277 protein, expressed by HEK293 , with tag free. The total length of BTN3A1/CD277 Protein, Human (HEK293) is 225 a.a., with molecular weight of 26-32 KDa.

BTN3A1/CD277 蛋白参与与 T 细胞激活和适应性免疫反应相关的重要功能。它充当激活的 T 细胞增殖的调节剂，并控制这些细胞释放细胞因子和 IFNG。此外，它还介导 T 细胞对磷酸化代谢物（如异戊烯基焦磷酸）水平升高的感染和转化细胞的反应。BTN3A1/CD277 蛋白作为同二聚体发挥作用。

Immobilized Human BTN3A1, No Tag at 0.5 μg/mL(100 μl/well) on the plate. Dose response curve for Anti-BTN3A1 Antibody, hFc Tag with the EC₅₀ of 8.8 ng/mL determined by ELISA.

Human

HEK293

Tag Free

O00481 (Q30-G254)

11119  [NCBI]

26-32 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.