2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. SM27

SM27 (NSC 37204) 是成纤维细胞生长因子 (FGF) 的抑制剂。SM27 通过阻断 FGF2/HSPGs/FGFR1 复合物形成抑制血管生成。

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SM27 Chemical Structure

SM27 Chemical Structure

CAS No. : 6266-54-2

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SM27 相关抗体

Top Publications Citing Use of Products

查看 FGFR 亚型特异性产品:

查看所有亚型
FGFR FGFR1 FGFR2 FGFR3 FGFR4 FGF21

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation[1].

体外研究
(In Vitro)

SM27 (0-100 μM, 2 h) 通过抑制 FGF2 介导的细胞-细胞粘附 (IC50为1 mM)，剂量依赖性地抑制 FGF2/肝素和 FGF2/ FGFR1 相互作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SM27 相关抗体:
分子量

504.49

Formula

C21H16N2O9S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SM27 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SM276266-54-2NSC 37204SM 27SM-27NSC37204NSC-37204FGFRFibroblast growth factor receptorantiangiogeniccell-cell adhesionCHO cellsInhibitorinhibitorinhibit

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