1. Gene
  2. CLGN - calmegin Gene

CLGN - calmegin Gene

中文名称:镇定因子

种属: Homo sapiens

基因 ID: 1047 | 基因类型: protein coding

关于 CLGN

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:140,388,453-140,427,648 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 3 paralogues. Biased expression in testis (RPKM 66.0), heart (RPKM 22.6) and 2 other tissues.

功能概要

Calmegin 是一种睾丸特异性内质网伴侣蛋白。 CLGN 可能在精子发生和不育中发挥作用。[RefSeq 提供,2008 年 7 月]

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]

CLGN 基因产物(2)

mRNA Protein Name
NM_001130675.2 NP_001124147.1 calmegin precursor
NM_004362.3 NP_004353.1 calmegin precursor

CLGN 蛋白结构

Calreticulin

Calreticulin: Calreticulin family (60 - 429)

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  • 610 a.a.
蛋白主名 其他名称

calmegin

testis tissue sperm-binding protein Li 79P

重组 CLGN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7709 Calmegin/CLGN Protein, Human (HEK293, His) O14967-1 (E20-W471) ≥95%

关联疾病

疾病名称 别名
Colloid Adenoma

Macrofollicular Adenoma

Carotid Artery Dissection

Dissection Of Carotid Artery

Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus CLGN VGNC VGNC:60957
Mus musculus CLGN MGD MGI:107472
Macaca mulatta CLGN VGNC VGNC:71253
Rattus norvegicus CLGN RGD RGD:1592643
Canis familiaris CLGN VGNC VGNC:39336
Bos taurus CLGN VGNC VGNC:27437
Others CLGN NCBI