1. Gene
  2. NXPH1 - neurexophilin 1 Gene

NXPH1 - neurexophilin 1 Gene

中文名称:亲神经素 1

种属: Homo sapiens

同用名: NPH1; Nbla00697

基因 ID: 30010 | 基因类型: protein coding

关于 NXPH1

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:8,433,609-8,752,961 (from NCBI)

This gene has 5 transcripts (splice variants), 272 orthologues and 3 paralogues. Biased expression in adrenal (RPKM 15.5) and brain (RPKM 12.8).

功能概要

该基因是 neurexophilin 家族的成员,编码具有可变 N 末端结构域、高度保守的 N-糖基化中心结构域、短连接区和富含半胱氨酸的 C 末端结构域的分泌蛋白。这种蛋白质与 alpha neurexins 形成非常紧密的复合物,alpha neurexins 是一组促进树突和轴突之间粘附的蛋白质。[RefSeq 提供,2008 年 7 月]

This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. [provided by RefSeq, Jul 2008]

NXPH1 基因产物(1)

mRNA Protein Name
NM_152745.3 NP_689958.1 neurexophilin-1 precursor

NXPH1 蛋白结构

Neurexophilin

Neurexophilin: Neurexophilin (66 - 271)

  • 0
  • 100
  • 200
  • 271 a.a.
蛋白主名 其他名称

neurexophilin-1

重组 NXPH1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71178 NXPH1 Protein, Human (HEK293, His) P58417 (A22-G271) ≥95%

关联疾病

疾病名称 别名
Constipation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus NXPH1 MGD MGI:107492
Bos taurus NXPH1 VGNC VGNC:50069
Felis catus NXPH1 VGNC VGNC:63939
Rattus norvegicus NXPH1 RGD RGD:3218
Canis familiaris NXPH1 VGNC VGNC:44077
Macaca mulatta NXPH1 VGNC VGNC:81732
Others NXPH1 NCBI