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  3. HBP1 - HMG-box transcription factor 1 Gene

HBP1 - HMG-box transcription factor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：HMG-box 转录因子 1

种属: Homo sapiens

基因 ID: 26959 | 基因类型: protein coding

关于 HBP1

Cytogenetic location: 7q22.3 Genomic coordinates (GRCh38): 7:107,169,003-107,202,522 (from NCBI)

This gene has 15 transcripts (splice variants), 1 gene allele and 268 orthologues. Ubiquitous expression in thyroid (RPKM 32.0), endometrium (RPKM 26.6) and 25 other tissues.

功能概要

预测可实现 DNA 结合转录抑制活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。预计参与脂质转运的负调控；活性氧生物合成过程的负调控； RNA 聚合酶 II 对转录的负调控。位于核斑点。骨关节炎的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of lipid transport; negative regulation of Reactive Oxygen Species biosynthetic process; and negative regulation of transcription by RNA polymerase II. Located in nuclear speck. Biomarker of osteoarthritis. [provided by Alliance of Genome Resources, Apr 2022]

HBP1 基因产物(2)

mRNA Protein Name
NM_001244262.2 NP_001231191.1 HMG box-containing protein 1 isoform 1
NM_012257.4 NP_036389.2 HMG box-containing protein 1 isoform 2

HBP1 蛋白结构

AXH

AXH: Ataxin-1 and HBP1 module (AXH) (215 - 339)

HMG_box

HMG_box: HMG (high mobility group) box (435 - 499)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 514 a.a.
蛋白主名 其他名称

HMG box-containing protein 1

high mobility group box transcription factor 1

重组 HBP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75150 HBP1 Protein, Human (His) O60381 (P208-F345) ≥95%

关联疾病

疾病名称 别名
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06033 HBP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus HBP1 RGD RGD:620444
Bos taurus HBP1 VGNC VGNC:29767
Canis familiaris HBP1 VGNC VGNC:41611
Felis catus HBP1 VGNC VGNC:62763
Macaca mulatta HBP1 VGNC VGNC:73218
Mus musculus HBP1 MGD MGI:894659
Others HBP1 NCBI
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