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  2. STX7 - syntaxin 7 Gene

STX7 - syntaxin 7 Gene

中文名称:突触蛋白 7

种属: Homo sapiens

基因 ID: 8417 | 基因类型: protein coding

关于 STX7

Cytogenetic location: 6q23.2 Genomic coordinates (GRCh38): 6:132,445,867-132,513,472 (from NCBI)

This gene has 4 transcripts (splice variants), 210 orthologues and 12 paralogues. Ubiquitous expression in lymph node (RPKM 31.8), spleen (RPKM 19.7) and 24 other tissues.

功能概要

该基因编码的蛋白质是参与囊泡运输的突触融合蛋白家族膜受体。编码的蛋白质结合 alpha-SNAP,这是运输囊泡融合的重要调节剂。与突触融合蛋白 13 一起,该蛋白质在内体和溶酶体与吞噬体的有序融合中发挥作用。[RefSeq 提供,2016 年 5 月]

The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016]

STX7 基因产物(4)

mRNA Protein Name
NM_001326578.2 NP_001313507.1 syntaxin-7 isoform a
NM_001326579.2 NP_001313508.1 syntaxin-7 isoform a
NM_001326580.2 NP_001313509.1 syntaxin-7 isoform b
NM_003569.3 NP_003560.2 syntaxin-7 isoform a

STX7 蛋白结构

Syntaxin_2

Syntaxin_2: Syntaxin-like protein (18 - 118)

SNARE

SNARE: SNARE domain (170 - 232)

  • 0
  • 100
  • 200
  • 261 a.a.
蛋白主名 其他名称

syntaxin-7

重组 STX7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71024 STX7 Protein, Human (HEK293, His) O15400 (S2-L238) ≥95%
HY-P73621 Syntaxin-7 Protein, Human (HEK293, His) O15400 (S2-L238) ≥95%

关联疾病

疾病名称 别名
Neuronal Migration Disorders

Abnormality Of Neuronal Migration

Malformations Of Cortical Development, Group Ii

Neuronal Dysmigration Syndromes

Hemophagocytic Lymphohistiocytosis, Familial, 4

Familial Hemophagocytic Lymphohistiocytosis 4

FHL4

Hplh4

Hlh4

Lymphohistiocytosis, Hemophagocytic, Familial, Type 4

Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris STX7 VGNC VGNC:46958
Macaca mulatta STX7 VGNC VGNC:78047
Bos taurus STX7 VGNC VGNC:35443
Rattus norvegicus STX7 RGD RGD:619747
Mus musculus STX7 MGD MGI:1858210
Felis catus STX7 VGNC VGNC:102526
Others STX7 NCBI