2. Gene
  3. NOL3 - nucleolar protein 3 Gene

NOL3 - nucleolar protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核仁蛋白 3

种属: Homo sapiens

同用名: ARC; FCM; MYP; NOP; NOP30; MYOCL1

基因 ID: 8996 | 基因类型: protein coding

关于 NOL3

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,170,538-67,175,737 (from NCBI)

This gene has 13 transcripts (splice variants), 89 orthologues, 1 paralogue and is associated with 2 phenotypes. Ubiquitous expression in skin (RPKM 15.7), prostate (RPKM 15.6) and 24 other tissues.

功能概要

该基因编码一种抗凋亡蛋白，该蛋白已被证明可下调半胱天冬酶 2、半胱天冬酶 8 和肿瘤蛋白 p53 的酶活性。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2010 年 6 月]

This gene encodes an anti-apoptotic protein that has been shown to down-regulate the Enzyme activities of Caspase 2, Caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

NOL3 基因产物(13)

mRNA Protein Name
NM_001185057.3 NP_001171986.1 nucleolar protein 3 isoform Nop30
NM_001276307.3 NP_001263236.1 nucleolar protein 3 isoform MYP
NM_001276309.3 NP_001263238.1 nucleolar protein 3 isoform MYP
NM_001276311.2 NP_001263240.1 nucleolar protein 3 isoform C
NM_001276312.3 NP_001263241.1 nucleolar protein 3 isoform MYP
NM_001394973.1 NP_001381902.1 nucleolar protein 3 isoform MYP
NM_001394974.1 NP_001381903.1 nucleolar protein 3 isoform C
NM_001394975.1 NP_001381904.1 nucleolar protein 3 isoform C
NM_001394976.1 NP_001381905.1 nucleolar protein 3 isoform C
NM_001394977.1 NP_001381906.1 nucleolar protein 3 isoform Nop30
NM_001394978.1 NP_001381907.1 nucleolar protein 3 isoform Nop30
NM_001394979.1 NP_001381908.1 nucleolar protein 3 isoform E
NM_003946.7 NP_003937.1 nucleolar protein 3 isoform MYP

NOL3 蛋白结构

CARD

CARD: Caspase recruitment domain (10 - 95)

  • 0
  • 100
  • 208 a.a.
蛋白主名 其他名称

nucleolar protein 3

muscle-enriched cytoplasmic protein

重组 NOL3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7540 ARC Protein, Human O60936 (M1-S208) ≥95%

关联疾病

疾病名称 别名
Myoclonus, Familial, 1

Myoclonus, Familial Cortical

MYOCL1

Fcm

Familial Cortical Myoclonus
Myoclonus
Ischemia

Acute Coronary Syndrome
Ulcerative Stomatitis

Stomatitis Ulcerative

Aphthous Stomatitis

Minor Oral Aphthous Ulceration
Familial Adult Myoclonic Epilepsy

Benign Adult Familial Myoclonus Epilepsy

Bafme

Benign Adult Familial Myoclonic Epilepsy

Fame

Familial Cortical Myoclonic Tremor And Epilepsy

Fcmte

Adcme

Autosomal Dominant Cortical Myoclonus And Epilepsy

Fam

Epilepsy, Myoclonic, Familial Adult

Epilepsy, Myoclonic, Benign Adult Familial, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09414 NOL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NOL3 RGD RGD:708558
Bos taurus NOL3 VGNC VGNC:32156
Felis catus NOL3 VGNC VGNC:68512
Macaca mulatta NOL3 VGNC VGNC:99529
Mus musculus NOL3 MGD MGI:1925938
Others NOL3 NCBI
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