2. Membrane Transporter/Ion Channel Anti-infection
  3. Sodium Channel Parasite
  4. Quinidine

Quinidine 是 Quinine (HY-D0143) 的一种立体异构体，是从南美金鸡纳树的树皮中提取的天然化合物。Quinidine 是已知最早的抗心律失常剂之一，可作为 1a 类抗心律失常药物和抗疟剂。Quinidine 抑制快速向内的钠电流，导致动作电位 0 期的抑制。这种机制抑制了心肌的兴奋性，最终导致动作电位持续时间延长和自动性降低。Quinidine 对快速向内的钠电流表现出 “使用依赖性阻断” 效应，这意味着试剂的影响在较高的心率时增加，在较低的心率时减少。Quinidine 可用于恶性疟原虫疟疾和室性心律失常的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Quinidine Chemical Structure

Quinidine Chemical Structure

CAS No. : 56-54-2

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Quinidine:

Quinidine 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Quinidine is a stereoisomer of Quinine (HY-D0143), a natural compound derived from the bark of the South American cinchona tree. Quinidine is one of the earliest known antiarrhythmic agents and is available as a Class 1a antiarrhythmic and antimalarial drug. Quinidine inhibits the rapid inward sodium current, resulting in the suppression of action potential phase 0. This mechanism suppresses the excitability of the heart muscle, ultimately leading to longer duration of action potentials and reduced automaticity. Quinidine shows a "use-dependent blocking" effect on the rapidly inward sodium current, meaning that the drug's effects increases at higher heart rates and decreases at lower heart rates.Quinidine can be used in the study of Plasmodium falciparum malaria and ventricular arrhythmias[1].

分子量

324.42

Formula

C20H24N2O2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Quinidine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quinidine56-54-2Sodium ChannelParasiteNa channelsNa+ channelsStereoisomersnatural compoundsarrhythmiasmalariaInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Quinidine
目录号：
HY-B1751H
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z