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  4. FD44

FD44 是一种吩噻嗪小分子，可抑制神经元钙传感器 1 (NCS-1) 和鸟嘌呤交换因子 Ric8a 之间的相互作用。而 Ric8a 是突触数量和神经递质释放概率的关键调节因子。在果蝇遗传性自闭症脆性 X 综合征 (FXS) 模型中，FD44 可恢复正常的突触数量和联想学习。

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FD44 Chemical Structure

FD44 Chemical Structure

CAS No. : 68207-21-6

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FD44 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FD44 is a phenothiazine small molecule that inhibits the interaction between neuronal calcium sensor 1 (NCS-1) and the guanine exchange factor Ric8a, a key regulator of synapse number and neurotransmitter release probability. In the Drosophila genetic autism model of fragile X syndrome (FXS), FD44 restored normal synapse number and associative learning[1].

分子量

339.45

Formula

C19H21N3OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FD44 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FD4468207-21-6FD 44FD-44OthersInhibitorinhibitorinhibit

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