1. Gene
  2. SLCO3A1 - solute carrier organic anion transporter family member 3A1 Gene

SLCO3A1 - solute carrier organic anion transporter family member 3A1 Gene

中文名称:溶质载体有机阴离子转运蛋白家族成员 3A1

种属: Homo sapiens

同用名: OATPD; OATP-D; OATP3A1; OATPRP3; OATP-RP3; SLC21A11

基因 ID: 28232 | 基因类型: protein coding

关于 SLCO3A1

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:91,853,708-92,172,435 (from NCBI)

This gene has 13 transcripts (splice variants), 264 orthologues and 10 paralogues. Broad expression in testis (RPKM 11.4), lung (RPKM 6.4) and 23 other tissues.

功能概要

预计可实现不依赖钠的有机阴离子跨膜转运蛋白活性。参与 NF-kappaB 转录因子活性的正调控;蛋白质磷酸化的正调节;和前列腺素运输。位于质膜。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable sodium-independent organic anion transmembrane transporter activity. Involved in positive regulation of NF-kappaB transcription factor activity; positive regulation of protein phosphorylation; and prostaglandin transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLCO3A1 基因产物(2)

mRNA Protein Name
NM_001145044.1 NP_001138516.1 solute carrier organic anion transporter family member 3A1 isoform 2
NM_013272.4 NP_037404.2 solute carrier organic anion transporter family member 3A1 isoform 1

SLCO3A1 蛋白结构

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (39 - 623)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (477 - 527)

  • 0
  • 200
  • 400
  • 600
  • 710 a.a.
蛋白主名 其他名称

solute carrier organic anion transporter family member 3A1

PGE1 transporter

关联疾病

疾病名称 别名
Intestinal Perforation

Perforation Of Intestine

Primary Hypertrophic Osteoarthropathy

Pachydermoperiostosis Syndrome

Osteoarthropathy, Primary Hypertrophic

Pachydermoperiostosis Of Nail

Idiopathic Hypertrophic Osteoarthropathy

Pho

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SLCO3A1 RGD RGD:620227
Felis catus SLCO3A1 VGNC VGNC:65446
Canis familiaris SLCO3A1 VGNC VGNC:46497
Macaca mulatta SLCO3A1 VGNC VGNC:77598
Bos taurus SLCO3A1 VGNC VGNC:34953
Mus musculus SLCO3A1 MGD MGI:1351867