2. Academic Validation
  3. Synthesis and immunostimulating properties of novel adamant-1-yl tripeptides

Synthesis and immunostimulating properties of novel adamant-1-yl tripeptides

  • Chem Biodivers. 2012 Apr;9(4):777-88. doi: 10.1002/cbdv.201100232.
Rosana Ribić 1,  Lidija Habjanec,  Branka Vranešić,  Ruža Frkanec,  Srđanka Tomić
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Zagreb, Zagreb, Croatia.
PMID: 22492495 DOI: 10.1002/cbdv.201100232
Abstract

The aim of this work was to prepare L- and D-(adamant-1-yl)-Gly-L-Ala-D-isoGln Peptides in order to study their Adjuvant (immunostimulating) activities. Adjuvant activity of adamant-1-yl Tripeptides was tested in the mouse model using ovalbumin as an antigen and in comparison to the peptidoglycan monomer (PGM; β-D-GlcNAc-(1→4)-D-MurNAc-L-Ala-D-isoGln-mesoDAP(εNH(2) )-D-Ala-D-Ala) and structurally related adamant-2-yl Tripeptides.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z