2. Metabolic Enzyme/Protease MAPK/ERK Pathway GPCR/G Protein
  3. Endogenous Metabolite Ras
  4. 6-T-GDP

6-T-GDP  (Synonyms: 6-Thioguanosine 5'-diphosphate)

目录号: HY-134243
产品使用指南

摩尔计算器

6-T-GDP (6-Thioguanosine 5'-diphosphate) 是硫唑嘌呤的代谢产物。6-T-GDP 通过抑制 Rac1 的活性，能够减少炎症因子的转录和细胞粘附分子的表达，从而抑制白细胞的迁移和组织炎症的发生。

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6-T-GDP Chemical Structure

6-T-GDP Chemical Structure

CAS No. : 16541-19-8

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6-T-GDP 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of azathioprine. 6-T-GDP can reduce the transcription of inflammatory factors and the expression of cell adhesion molecules by inhibiting the activity of Rac1, thereby inhibiting the migration of leukocytes and the occurrence of tissue inflammation[1].

分子量

459.27

Formula

C10H15N5O10P2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

6-T-GDP 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-T-GDP16541-19-86-Thioguanosine 5'-diphosphateEndogenous MetaboliteRasMetaboliteInflammationLeukocytesRac1Cell adhesion moleculeInhibitorinhibitorinhibit

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