Ras Inhibitors

K-Ras

H-Ras

N-Ras

Ras

Ras Degraders, Inhibitors & Antagonists

Product Name	K-Ras	H-Ras	N-Ras	Ras	Purity
Sotorasib	KRAS(G12C)				99.94%
MRTX1133	KRas G12D, Kd: 0.2 pM				99.97%
Adagrasib	KRas G12C				99.93%
RMC-6236	KRas G12D				99.88%
HRS-4642	KRas G12D, Ki: 0.083 nM
RMC-7977	KRAS(G12C)	H-Ras	NRAS rG4		99.48%
BI-3406	KRAS-SOS1, IC₅₀: 6 nM				99.95%
BI-2852	KRAS(G12C), IC₅₀: 450 nM KRAS(G12C), Kd: 750 nM				99.57%
RMC-9805	KRAS(G12D)				99.73%
Divarasib	K-Ras(G12C), IC₅₀: <0.01 μM				99.46%
RMC-6291	KRAS(G12C)				99.65%
MRTX0902	KRAS-SOS1, IC₅₀: 46 nM				99.75%
BAY-293	KRAS-SOS1, IC₅₀: 21 nM				98.91%
LC-2	KRAS(G12C), DC₅₀: 0.25-0.76 μM				98.04%
Opnurasib	KRas G12C				98.94%
ARS-1620	KRAS(G12C)				99.62%
Sotorasib racemate	KRas G12C				98.99%
Pan KRas-IN-1	KRas G12D, IC₅₀: 9 nM KRas G12S, IC₅₀: 11 nM KRas G12C, IC₅₀: 6 nM KRas Q61H, IC₅₀: 12 mM KRas G12V, IC₅₀: 29 mM K-Ras WT, IC₅₀: 32 nM				98.47%
MRTX-1257	KRAS(G12C)				99.14%
BI-2493	K-Ras WT				99.79%
DCC-3116	KRas G12C				99.25%
PROTAC K-Ras Degrader-1	KRAS(G12C)				98.05%
Setidegrasib	KRAS(G12D)				99.65%
ARS-853	KRAS(G12C), IC₅₀: 2.5 μM				98.39%
KRAS inhibitor-3	K-Ras WT, EC₅₀: 0.28 μM KRAS(G12C), EC₅₀: 0.63 μM KRas G12D, EC₅₀: 0.37 μM KRas Q61H, EC₅₀: 0.74 μM				99.65%
XRP44X				Ras, IC₅₀: 10 nM	98.42%
RM-018	KRAS (G12C) KRAS (G12C/Y96D)				98.03%
MRTX-EX185 formic	KRas G12D, IC₅₀: 90 nM
ARS-1323-alkyne	KRAS(G12C)				99.59%
KRAS G12D inhibitor 14	KRas G12D, Kd: 33 nM				99.39%
SAH-SOS1A TFA	KRas G12C, EC₅₀: 140 nM KRas G12D, EC₅₀: 109 nM KRas G12V, EC₅₀: 154 nM KRas G12S, EC₅₀: 155 nM KRas Q61H, EC₅₀: 175 nM K-Ras WT, EC₅₀: 106 nM				99.16%
MCP110				Ras	99.82%
KRpep-2d	K-RAS
ASP2453	KRas G12C, IC₅₀: 40 nM				98.04%
SOS1-IN-15	SOS1, IC₅₀: 5 nM				99.51%
Kobe0065		H-Ras			98.01%
AZD4625	KRAS(G12C)				99.52%
BI-0474	KRAS-SOS1, IC₅₀: 7.0 nM				99.83%
ARS-1323	KRas G12C				99.67%
KRAS G12C inhibitor 14	KRas G12C, IC₅₀: 18 nM				98.07%
KRAS inhibitor-10	KRas G12C				99.92%
Fulzerasib	KRAS(G12C)				99.60%
RAS/RAS-RAF-IN-1				Ras	99.81%
KRAS G12C inhibitor 15	KRas G12C, IC₅₀: 5 nM				98.47%
Pan-RAS-IN-4	KRas G12D				98.53%
Sotorasib-d₇	KRAS(G12C)
ARS-1630	KRAS(G12C)				98.10%
Spiclomazine	KRAS(G12C)				99.95%
KRAS G12C inhibitor 28	KRas G12C, IC₅₀: 57 nM				99.94%
KRpep-2d TFA	K-RAS				98.11%
Kras4B G12D-IN-1	KRas G12D				98.01%
TH-Z835	KRAS(G12D), IC₅₀: 1.6 μM				99.58%
KRAS G12D inhibitor 3 TFA	KRas G12D, IC₅₀: <500 nM				98.18%
PROTAC K-Ras Degrader-4	K-RAS
Atrovastatin-PEG3-FITC	KRAS-PDEδ				98.17%
KRas G12C inhibitor 1	KRas G12C
CFL-137	KRAS(G12C)				99.84%
K-Ras G12C-IN-2	KRas G12C				99.21%
KRAS inhibitor-7	KRAS(G12C)
KRAS inhibitor-6	KRAS(G12C)
KRAS inhibitor-8	KRAS(G12C)
KRAS G12C inhibitor 32	KRAS (G12C)
KRAS G12D inhibitor 3	KRas G12D, IC₅₀: <500 nM
KRAS G12C inhibitor 27	KRas G12C
KRAS inhibitor-14	KRas G12C, IC₅₀: 0.249 μM
KRAS G12C inhibitor 18	KRas G12C
KRAS G12C inhibitor 17	KRas G12C, IC₅₀: 5 nM
KRAS inhibitor-20	KRAS(G12C), IC₅₀: <10 nM (^[1])
KRAS G12C inhibitor 16	KRas G12C, IC₅₀: 97 nM
ASP6918	KRas G12C, IC₅₀: 0.028 μM
KRAS inhibitor-16	KRas G12C, IC₅₀: 0.457 μM
KRAS G12C inhibitor 13	KRas G12C
G12Si-1	KRas G12S
SOS1-IN-8	SOS1-G12D, IC₅₀: 11.6 nM SOS1-G12V, IC₅₀: 40.7 nM
TH-Z827	KRAS(G12D), IC₅₀: 2.4 μM
KRAS G12C inhibitor 43	KRas G12C
CFL-120	KRAS(G12C)				≥98.0%
KRAS G12C inhibitor 61	K-Ras WT
KRAS G12C inhibitor 53	KRAS(G12C)
KRAS inhibitor-31	KRas G12D, Kd: 0.019 nM KRas G12C, Kd: 0.019 nM KRas G12V, Kd: 0.096 nM
PROTAC K-Ras Degrader-5	KRas G12D, DC₅₀: <100 nM
K-Ras-IN-3	KRas G12V, IC₅₀: 0.371 nM
SOS1-IN-9	KRAS G12C-SOS1, IC₅₀: 116.5 nM
KRAS inhibitor-13	KRas G12C, IC₅₀: 0.883 μM
PROTAC K-Ras Degrader-3	KRas G12D
KRAS G12C inhibitor 44	KRas G12C
KRAS inhibitor-17	KRas G12C, IC₅₀: 3.37 μM
KRAS inhibitor-24	KRas G12V, IC₅₀: < 100 nM K-Ras WT, IC₅₀: < 100 nM KRas G12R, IC₅₀: < 100 nM
KRAS G12C inhibitor 45	KRas G12C
pan-KRAS-IN-6	KRas G12D, IC₅₀: 9.79 nM KRas G12V, IC₅₀: 6.03 nM
KRAS inhibitor-11	K-RAS
pan-KRAS-IN-16	KRas G12D	H-Ras		Ras
KRAS G12C inhibitor 55	KRAS(G12C)
KRASG12C IN-14	KRas G12C
MRTX849 ethoxypropanoic acid	KRas G12C
KRAS G12D inhibitor 16	KRas G12D, IC₅₀: 0.7 nM
SOS1-IN-7	SOS1-G12D, IC₅₀: 20 nM SOS1-G12V, IC₅₀: 67 nM
KRASG12C IN-12	KRas G12C
SAH-SOS1A	KRas G12C, EC₅₀: 140 nM KRas G12D, EC₅₀: 109 nM KRas G12V, EC₅₀: 154 nM KRas G12S, EC₅₀: 155 nM KRas Q61H, EC₅₀: 175 nM K-Ras WT, EC₅₀: 106 nM
KRAS G12C inhibitor 59	KRas G12C
KRAS inhibitor-34	K-RAS, : 6.4 nM
KRAS G12C inhibitor 52	KRAS(G12C)
PROTAC K-Ras Degrader-6	KRas G12D, DC₅₀: >100 nM
KRAS inhibitor-12	KRas G12C, IC₅₀: 0.537 μM
KRAS inhibitor-26	KRas G12V, IC₅₀: <100 nM
SOS1-IN-10	KRAS G12C-SOS1, IC₅₀: 13 nM
pan-KRAS-IN-15	K-RAS, IC₅₀: 1.4 nM
MRTX849 acid	KRas G12C				99.84%
SIAIS562055	SOS1, Kd: 95.9 nM
KRAS inhibitor-15	KRas G12C, IC₅₀: 0.954 μM
KRAS G12C inhibitor 47	KRas G12C, IC₅₀: 0.172 μM
KRAS inhibitor-25	KRas G12C, IC₅₀: < 100 nM K-Ras WT, IC₅₀: < 100 nM KRas G12R, IC₅₀: < 100 nM
pan-KRAS-IN-13	KRas G12D, IC₅₀: 2.75 nM KRas G12V, IC₅₀: 2.89 nM
KRAS G12C inhibitor 57	KRAS(G12C), IC₅₀: 0.21 μM (KRAS G12C/SOS1 binding assay)
KRAS G12C inhibitor 51	KRAS(G12C)
KRAS G12C inhibitor 26	KRas G12C
KRAS G12C inhibitor 46	KRas G12C
pan-KRAS-IN-3	K-Ras WT
(4S)-PROTAC SOS1 degrader-1	K-RAS
KRAS G12C inhibitor 48	KRas G12C, IC₅₀: 639.91 nM
KRAS G12D inhibitor 7	KRas G12D
K-Ras(G12C) inhibitor 6	K-Ras(G12C)				99.08%
KRAS G12C inhibitor 23	KRas G12C
KRAS G12C inhibitor 68	KRas G12C, IC₅₀: 7 nM
ZG1077	KRas G12C
PROTAC SOS1 degrader-3	SOS1
KRAS G12C inhibitor 50	KRAS(G12C), IC₅₀: 46.7 nM
Pan-RAS-IN-6	KRas G12C, IC₅₀: 1.3 nM KRas G12D, IC₅₀: 4.7 nM KRas G12V, IC₅₀: 0.3 nM
KRAS inhibitor-18	KRas G12C, IC₅₀: 4.74 μM
SOS1-IN-4	KRAS-C12C/SOS1, IC₅₀: 56 nM
KRAS inhibitor-37	K-Ras WT, Kd: 0.004 nM KRas G12D, Kd: 0.041 nM KRas G12C, Kd: 0.019 nM KRas G12V, Kd: 0.144 nM
K20	KRAS(G12C), IC₅₀: 1.16 μM
KRAS inhibitor-35	K-RAS, : 2 nM
KRAS G12D inhibitor 22	KRas G12D, IC₅₀: <100 nM
SOS1-IN-6	SOS1-G12D, IC₅₀: 14.9 nM SOS1-G12V, IC₅₀: 73.3 nM
KRAS G12D inhibitor 20	KRas G12D
KRAS G12D inhibitor 23	KRas G12D, IC₅₀: 0.007 μM
Anticancer agent 207			NRAS rG4, Kd: 2.31 μM
Spiclomazine hydrochloride	K-RAS
KRAS G12C inhibitor 25	KRas G12C
KRAS G12C inhibitor 54	KRAS(G12C)
pan-KRAS ligand 1	K-RAS
KRAS G12C inhibitor 62	KRas G12C
NHTD	K-RAS
KRAS inhibitor-23	K-RAS
KRAS G12C inhibitor 67	KRas G12C
6H05	K-Ras(G12C)
KRAS G12C inhibitor 5	KRas G12C
KRas G12C inhibitor 2	KRas G12C
KRas G12C inhibitor 4	KRas G12C
KRas G12C inhibitor 3	KRas G12C

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