1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Apolipoprotein

Apolipoprotein 

Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III. Specific apolipoproteins function in the regulation of lipoprotein metabolism through their involvement in the transport and redistribution of lipids among various cells and tissues, through their role as cofactors for enzymes of lipid metabolism, or through their maintenance of the structure of the lipoprotein particles.

Apolipoprotein 亚型特异性产品:

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-145727
    Volanesorsen Inhibitor
    Volanesorsen (ISIS 304801) 是一种载脂蛋白CIII (apo-CIII) mRNA 的反义寡核苷酸抑制剂,可以降低甘油三酯水平并改善胰岛素抵抗。Volanesorsen 可用于高甘油三酯血症,家族性乳糜小铁血症综合征和 2 型糖尿病的研究。
    Volanesorsen
  • HY-145727A
    Volanesorsen sodium Inhibitor
    Volanesorsen sodium 是一种反义寡核苷酸,靶向载脂蛋白 C-III (APOC3) mRNA,用于家族性乳糜酶血症综合征的相关研究。
    Volanesorsen sodium
  • HY-153491
    Olezarsen Inhibitor
    Olezarsen 是一种靶向肝脏 APOC3 mRNA 的反义寡核苷酸,抑制载脂蛋白 C-III (apoC-III) 的产生,用于降低高危或已确定心血管疾病患者的甘油三酯水平。
    Olezarsen
  • HY-153491A
    Olezarsen sodium Inhibitor
    Olezarsen sodium 是一种靶向肝脏 APOC3 mRNA 的反义寡核苷酸,抑制载脂蛋白C-III (apoC-III)的产生,用于降低高危或已确定心血管疾病患者的甘油三酯水平。
    Olezarsen sodium

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