2. Metabolic Enzyme/Protease
  3. Apolipoprotein
  4. 5(Z),11(Z),14(Z)-Eicosatrienoic acid

5(Z),11(Z),14(Z)-Eicosatrienoic acid  (Synonyms: Sciadonic acid)

目录号: HY-165061
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5(Z),11(Z),14(Z)-Eicosatrienoic acid (Sciadonic acid) 是一种多不饱和脂肪酸，来源于海岸松籽油、裸子植物的叶子和种子以及淡水腹足类动物。研究表明，当转基因小鼠的饮食中包含 5(Z)、11(Z)、14(Z)-二十碳三烯酸时，它可以降低高密度脂蛋白和 ApoA1 水平，这些转基因小鼠在表达人类 ApoA1 时，其高密度脂蛋白和 ApoA1 水平会降低。体外研究表明，它可以减少胆固醇外流，当以甲酯形式局部使用时，它可以缓解炎症过程，可能是通过取代磷脂池中的花生四烯酸并降低下游炎症介质（如前列腺素 E2 和白三烯）的浓度来实现的。

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5(Z),11(Z),14(Z)-Eicosatrienoic acid Chemical Structure

5(Z),11(Z),14(Z)-Eicosatrienoic acid Chemical Structure

CAS No. : 7019-85-4

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5(Z),11(Z),14(Z)-Eicosatrienoic acid 相关抗体

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  • 生物活性

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生物活性

5(Z),11(Z),14(Z)-Eicosatrienoic acid (Sciadonic acid), a polyunsaturated fatty acid sourced from maritime pine seed oil, gymnospermae leaves and seeds, and freshwater gastropods, has been shown to reduce high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1 when included in their diet. In vitro studies indicate that it diminishes cholesterol efflux, and when applied topically in its methyl ester form, it alleviates inflammatory processes, likely by displacing arachidonic acid from phospholipid pools and lowering concentrations of downstream inflammatory mediators such as prostaglandin E2 and leukotrienes.

分子量

306.48

Formula

C20H34O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

5(Z),11(Z),14(Z)-Eicosatrienoic acid 相关分类

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Keywords:

5(Z),11(Z),14(Z)-Eicosatrienoic acid7019-85-4Sciadonic acidApolipoproteinInhibitorinhibitorinhibit

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