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Heparastatin 是乙酰肝素酶 (heparanase) 的一个抑制剂。

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Heparastatin Chemical Structure

Heparastatin Chemical Structure

CAS No. : 153758-25-9

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  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Heparastatin is a heparanase inhibitor.

IC50 & Target

heparanase[1].

体外研究
(In Vitro)

Addition of 100 μM of Heparastatin (SF4) completely inhibits the enzyme activity of heparanase at a concentration of 0.15 μg/mL in an in vitro degradation assay. Addition of Heparastatin during the transition process does not affect the phenotypic change of TGF-β-treated cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

272.18

Formula

C8H11F3N2O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
Cell Assay
[2]

Influence of a heparanase inhibitor on TGF-β3-induced EMT of NMuMG cells. NMuMG cells are cultured with 1 ng/mL TGF-β3 together with 10 or 100 μM Heparastatin (SF4) for 48 h[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

Heparastatin 相关分类

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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Heparastatin
目录号:
HY-100899
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