Leptin 抗体

Leptin Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Leptin, with a predicted molecular weight of 16 kDa . Leptin Antibody can be used for IHC-P, IHC-F, ICC/IF, ELISA experiments in human, mouse, rat, pig, sheep backgrounds.

The related gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. The protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiorelated genesis, reproduction, bone formation and wound healing. Mutations in The related gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in The related gene has also been linked to type 2 diabetes mellitus development.

3952

Predicted band size: 16 kDa

Affinity Purified

Secreted.

Non-conjugated

Unmodified

Primary Antibody; Rabbit Polyclonal Antibody

Polyclonal

Rabbit

Human, Mouse, Rat, Pig, Sheep

P41159

WB: 1/500-2000; ELISA: 1/5000-10000; IHC-P: 1/100-500; IHC-F: 1/100-500; IF=1/100-500;

IHC-P, IHC-F, ICC/IF, ELISA

液体

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

KLH conjugated synthetic peptide derived from human Leptin: 17-100/167