1. Apoptosis
  2. Apoptosis
  3. Anticancer agent 104

Anticancer agent 104 具有抗癌活性,并诱导癌细胞凋亡。

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Anticancer agent 104 Chemical Structure

Anticancer agent 104 Chemical Structure

CAS No. : 3047612-51-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 104 has anticancer activity, and induces cancer cell apoptosis[1].

体外研究
(In Vitro)

Anticancer agent 104 (Compound 4l) (48 h) 对 HepG2 细胞具有毒性 (IC50: 31.39 μM)[1].
Anticancer agent 104 (10-200 μg/mL, 48 h) 体积缩小,染色质边缘化,最终形成凋亡小泡[1]
Anticancer agent 104 (10-100 μg/mL, 48 h) 诱导HepG2细胞凋亡[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: Calu-1, SK-BR-3, HUH-7, 786-O, SK-OV-3 cells
Concentration: 0-200 μM approximately
Incubation Time: 48 h
Result: Shows cytotoxic activities with IC50s of 78.34, 44.18, 75.18, 91.67, 112.19 μM.

Apoptosis Analysis[1]

Cell Line: HepG2 cells
Concentration: 10, 50 and 100 μg/mL
Incubation Time: 48 h
Result: Showed apoptotic rate of 23.67%, 41.21% and 61.16% respectively.
分子量

636.87

Formula

C34H47F3N2O2S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anticancer agent 104 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anticancer agent 104
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