1. Apoptosis
  2. Apoptosis
  3. Anticancer agent 220

Anticancer agent 220 是一种具有抗癌作用的色满酮衍生物。Anticancer agent 220 在结肠癌细胞系中表现出很强的活性。Anticancer agent 220 诱导细胞凋亡 (apoptosis) 和细胞周期停滞。

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Anticancer agent 220 Chemical Structure

Anticancer agent 220 Chemical Structure

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 220 is a chromanone derivative with anticancer effects. Anticancer agent 220 shows highly potent activity in the colon cancer cell lines. Anticancer agent 220 induces apoptosis and cell cycle arrest in cells[1].

体外研究
(In Vitro)

Anticancer agent 220 (compound 14C) 在 HCT-116 细胞中表现出细胞毒性,IC50 为 53.3 µg/mL。Anticancer agent 220 诱导 HCT-116 细胞中的 DNA 碎片,下调 CDK4 以及抗凋亡基因 Bcl-2 的表达水平,上调促凋亡基因 P53 和 Bax 的表达[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

513.76

Formula

C22H19Cl3N2O6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anticancer agent 220 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anticancer agent 220
目录号:
HY-158407
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