1. Metabolic Enzyme/Protease
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  3. BP Lipid 142

BP Lipid 142 来自于专利 WO2018170306A1(Compound 261)。BP Lipid 142 是一种类似于SM-102的可电离氨基脂,丙醇胺头部改善mRNA的封装。这个脂质可用于mRNA的递送。

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BP Lipid 142 Chemical Structure

BP Lipid 142 Chemical Structure

CAS No. : 2244715-87-3

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生物活性

BP Lipid 142 is derived from patent WO2018170306A1 (Example 102). BP Lipid 142 is an ionizable amine lipid analogous to SM-102. The propanolamine head improves encapsulation of mRNA. The lipid has both esters at C6 and C8 position relative to the amine nitrogen. Ester linkages in the lipid tails are introduced into the structure to improve tissue clearance. The primary ester located at C6 is attached with a long (11-carbon) lipid tail. The lipid can be used for mRNA-based therapies.

分子量

724.19

Formula

C45H89NO5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
BP Lipid 142
目录号:
HY-W440787
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