1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog DNA Alkylator/Crosslinker
  3. CB10-277

CB10-277 是一种 Dacarbazine (HY-B0078) 类似物,能够介导 DNA 中 O6 位置的鸟嘌呤残基烷基化并随后降低淋巴细胞和肿瘤的 ATase 水平。CB10-277 可用于转移性恶性黑色素瘤的研究。

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CB10-277 Chemical Structure

CB10-277 Chemical Structure

CAS No. : 7203-91-0

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

CB10-277 is a Dacarbazine (HY-B0078) analog that mediates alkylation of guanine residues at the O6 position in DNA and subsequently reduces ATase levels in lymphocytes and tumors. CB10-277 is useful in the study of metastatic malignant melanoma[1].

分子量

193.20

Formula

C9H11N3O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
CB10-277
目录号:
HY-126160
需求量: