2. Apoptosis
  3. Apoptosis
  4. Chb-M′

Chb-M′  (Synonyms: RUNX-IN-1)

目录号: HY-155990
产品使用指南

摩尔计算器

Chb-M′ (Compound Conjugate 1) 与 RUNX 结合序列共价结合，并抑制 RUNX 蛋白与其靶位点的结合。Chb-M′ 诱导 p53 依赖性的细胞凋亡 (apoptosis)，并抑制细胞生长。Chb-M′ 抑制 PANC-1 异种移植小鼠的肿瘤生长。

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Chb-M′ Chemical Structure

Chb-M′ Chemical Structure

CAS No. : 2177285-35-5

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规格 价格 是否有货
1 mg ￥8600
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5 mg 现货 询问价格 & 货期

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Chb-M′ 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chb-M′ (Compound Conjugate 1) covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. Chb-M′ induces the p53-dependent apoptosis and inhibits cancer cell growth. Chb-M′ inhibits tumor growth in PANC-1 xenograft mice[1].

IC50 & Target

RUNX[1]
分子量

1524.52

Formula

C71H88Cl2N24O11
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Chb-M′ 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chb-M′2177285-35-5RUNX-IN-1ApoptosiscancertumorcovalentmedulloblastomaPANC-1 xenograftpancreatic cancerInhibitorinhibitorinhibit

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