2. Gene
  3. SLCO2B1 - solute carrier organic anion transporter family member 2B1 Gene

SLCO2B1 - solute carrier organic anion transporter family member 2B1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体有机阴离子转运家族成员 2B1

种属: Homo sapiens

同用名: OATPB; OATP-B; OATP2B1; SLC21A9

基因 ID: 11309 | 基因类型: protein coding

关于 SLCO2B1

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:75,151,107-75,206,549 (from NCBI)

This gene has 19 transcripts (splice variants), 205 orthologues and 10 paralogues. Broad expression in liver (RPKM 44.0), lung (RPKM 34.3) and 23 other tissues.

功能概要

该基因座编码膜蛋白的有机阴离子转运多肽家族的成员。由该基因座编码的蛋白质可能在调节胎盘对硫酸化类固醇的摄取中发挥作用。已经描述了选择性剪接的转录物变体。[RefSeq 提供，2010 年 11 月]

This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated Steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]

SLCO2B1 基因产物(3)

mRNA Protein Name
NM_001145211.3 NP_001138683.1 solute carrier organic anion transporter family member 2B1 isoform 2
NM_001145212.3 NP_001138684.1 solute carrier organic anion transporter family member 2B1 isoform 3
NM_007256.5 NP_009187.1 solute carrier organic anion transporter family member 2B1 isoform 1

SLCO2B1 蛋白结构

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (48 - 648)

  • 0
  • 200
  • 400
  • 600
  • 709 a.a.
蛋白主名 其他名称

solute carrier organic anion transporter family member 2B1

OATP-RP2

关联疾病

疾病名称 别名
Bronchiectasis 3
Ileum Cancer

Ileal Neoplasm

Malignant Neoplasm Of Ileum

Ileal Cancer

Ileal Neoplasms
Myasthenic Syndrome, Congenital, 1b, Fast-Channel

CMS1B

Congenital Myasthenic Syndrome 1b

Myasthenic Syndrome, Congenital, Fast-Channel

Congenital Myasthenic Syndrome 1b, Fast-Channel

Fccms

Myasthenic Syndrome, Fast-Channel Congenital

Myasthenic Syndrome, Congenital, Type 1b, Fast-Channel

Congenital Myasthenic Syndrome Ib
Bilirubin Metabolic Disorder

Hyperbilirubinemia

Hereditary Hyperbilirubinemia

Hyperbilirubinemia, Hereditary

Hyperbilirubinaemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13356 SLCO2B1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SLCO2B1 RGD RGD:621391
Macaca mulatta SLCO2B1 VGNC VGNC:77603
Mus musculus SLCO2B1 MGD MGI:1351872
Bos taurus SLCO2B1 VGNC VGNC:34952
Canis familiaris SLCO2B1 VGNC VGNC:46496
Felis catus SLCO2B1 VGNC VGNC:65445
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