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  2. LMTK3 - lemur tyrosine kinase 3 Gene

LMTK3 - lemur tyrosine kinase 3 Gene

中文名称:狐猴酪氨酸激酶 3

种属: Homo sapiens

同用名: LMR3; TYKLM3; PPP1R101

基因 ID: 114783 | 基因类型: protein coding

关于 LMTK3

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,485,271-48,513,680 (from NCBI)

This gene has 7 transcripts (splice variants), 147 orthologues and 1 paralogue. Biased expression in brain (RPKM 7.4), duodenum (RPKM 0.9) and 5 other tissues.

功能概要

预测启用蛋白激酶活性。预测参与蛋白质磷酸化。预测位于高尔基体膜;轴突;和树突。预计是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be located in Golgi membrane; axon; and dendrite. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LMTK3 基因产物(2)

mRNA Protein Name
NM_001080434.2 NP_001073903.2 serine/threonine-protein kinase LMTK3 precursor
NM_001388485.1 NP_001375414.1 serine/threonine-protein kinase LMTK3 precursor

LMTK3 蛋白结构

Pkinase_Tyr

Pkinase_Tyr: Protein tyrosine kinase (134 - 407)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1460 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase LMTK3

protein phosphatase 1, regulatory subunit 101

关联疾病

疾病名称 别名
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With Or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy

Catecholaminergic Polymorphic Ventricular Tachycardia 1

Ventricular Tachycardia, Catecholaminergic Polymorphic, 1

CPVT1

Ventricular Tachycardia, Stress-Induced Polymorphic

Vtsip

Bidirectional Tachycardia

Stress-Induced Polymorphic Ventricular Tachycardia

Cvpt1

Double Tachycardia Induced By Catecholamines

Malignant Paroxysmal Ventricular Tachycardia

Multifocal Ventricular Premature Beats

Paroxysmal Ventricular Fibrillation

Syncopal Paroxysmal Tachycardia

Syncopal Tachyarythmia

Ventricular Tachycardia Catecholaminergic Polymorphic 1

Tachycardia, Ventricular, Catecholaminergic Polymorphic, Type 1

Multifocal Pvcs

Multifocal Premature Ventricular Beats

Paroxysmal Familial Ventricular Fibrillation

Catecholaminergic Polymorphic Ventricular Tachycardia Type 1

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus LMTK3 VGNC VGNC:30942
Mus musculus LMTK3 MGD MGI:3039582
Rattus norvegicus LMTK3 RGD RGD:1588641
Others LMTK3 NCBI