1. Gene
  2. COX5B - cytochrome c oxidase subunit 5B Gene

COX5B - cytochrome c oxidase subunit 5B Gene

中文名称:细胞色素 c 氧化酶亚基 5B

种属: Homo sapiens

同用名: COXVB

基因 ID: 1329 | 基因类型: protein coding

关于 COX5B

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:97,646,062-97,648,383 (from NCBI)

This gene has 4 transcripts (splice variants) and 284 orthologues. Broad expression in colon (RPKM 200.2), kidney (RPKM 188.7) and 24 other tissues.

功能概要

细胞色素 C 氧化酶 (COX) 是线粒体呼吸链的末端酶。它是一种多亚基酶复合物,可将电子从细胞色素 c 转移到分子氧,并促进穿过线粒体内膜的质子电化学梯度。该复合体由 13 个线粒体和核编码的亚基组成。线粒体编码的亚基执行电子转移和质子泵送活动。核编码亚基的功能未知,但它们可能在复合体的调节和组装中发挥作用。该基因编码人线粒体呼吸链酶的核编码亚基 Vb。[RefSeq 提供,2008 年 7 月]

Cytochrome C oxidase (COX) is the terminal Enzyme of the mitochondrial respiratory chain. It is a multi-subunit Enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain Enzyme. [provided by RefSeq, Jul 2008]

COX5B 基因产物(1)

mRNA Protein Name
NM_001862.3 NP_001853.2 cytochrome c oxidase subunit 5B, mitochondrial precursor

COX5B 蛋白结构

COX5B

COX5B: Cytochrome c oxidase subunit Vb (3 - 124)

  • 0
  • 100
  • 129 a.a.
蛋白主名 其他名称

cytochrome c oxidase subunit 5B, mitochondrial

cytochrome c oxidase polypeptide VB, mitochondrial

重组 COX5B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75686 COX5B Protein, Human (His) P10606 (A32-H129) ≥95%

直系同源

种属 基因名 来源 基因 ID
Canis familiaris COX5B VGNC VGNC:39540
Rattus norvegicus COX5B RGD RGD:620608
Mus musculus COX5B MGD MGI:88475
Felis catus COX5B VGNC VGNC:103730
Others COX5B NCBI