1. Gene
  2. HECTD2 - HECT domain E3 ubiquitin protein ligase 2 Gene

HECTD2 - HECT domain E3 ubiquitin protein ligase 2 Gene

中文名称:HECT 结构域 E3 泛素蛋白连接酶 2

种属: Homo sapiens

基因 ID: 143279 | 基因类型: protein coding

关于 HECTD2

This gene has 6 transcripts (splice variants), 220 orthologues and 24 paralogues. Ubiquitous expression in prostate (RPKM 5.7), brain (RPKM 4.5) and 24 other tissues.

功能概要

预计会启用泛素蛋白转移酶活性。预测参与蛋白质泛素化。预测位于胞质溶胶中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

HECTD2 基因产物(4)

mRNA Protein Name
NM_001284274.3 NP_001271203.2 probable E3 ubiquitin-protein ligase HECTD2 isoform c
NM_001348365.2 NP_001335294.1 probable E3 ubiquitin-protein ligase HECTD2 isoform d
NM_173497.4 NP_775768.4 probable E3 ubiquitin-protein ligase HECTD2 isoform b
NM_182765.6 NP_877497.4 probable E3 ubiquitin-protein ligase HECTD2 isoform a

HECTD2 蛋白结构

HECT

HECT: HECT-domain (ubiquitin-transferase) (467 - 775)

  • 0
  • 200
  • 400
  • 600
  • 776 a.a.
蛋白主名 其他名称

probable E3 ubiquitin-protein ligase HECTD2

HECT domain containing E3 ubiquitin protein ligase 2

关联疾病

疾病名称 别名
Brain Compression

Compression Of Brain

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus HECTD2 VGNC VGNC:29801
Rattus norvegicus HECTD2 RGD RGD:1305536
Mus musculus HECTD2 MGD MGI:2442663
Canis familiaris HECTD2 VGNC VGNC:41643
Felis catus HECTD2 VGNC VGNC:62783
Macaca mulatta HECTD2 VGNC VGNC:73246