2. Gene
  3. TTC36 - tetratricopeptide repeat domain 36 Gene

TTC36 - tetratricopeptide repeat domain 36 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：四肽重复结构域 36

种属: Homo sapiens

同用名: HBP21

基因 ID: 143941 | 基因类型: protein coding

关于 TTC36

This gene has 3 transcripts (splice variants) and 188 orthologues. Biased expression in liver (RPKM 51.1), kidney (RPKM 9.2) and 2 other tissues.

功能概要

该基因编码的蛋白质具有三个四肽重复序列，是热休克蛋白 70 的伴侣蛋白。编码的蛋白质可能在肝细胞癌 (HCC) 中起肿瘤抑制因子的作用，因为它促进细胞凋亡但在 HCC 中下调。[RefSeq 提供，2016 年 9 月]

The protein encoded by this gene has three tetratricopeptide repeats and is a chaperone for heat shock protein 70. The encoded protein may function as a tumor suppressor in hepatocellular carcinoma (HCC) since it promotes Apoptosis but is downregulated in HCC. [provided by RefSeq, Sep 2016]

TTC36 基因产物(4)

mRNA Protein Name
NM_001080441.4 NP_001073910.1 tetratricopeptide repeat protein 36 isoform a
NM_001346096.2 NP_001333025.1 tetratricopeptide repeat protein 36 isoform b
NM_001346097.2 NP_001333026.1 tetratricopeptide repeat protein 36 isoform b
NM_001346098.2 NP_001333027.1 tetratricopeptide repeat protein 36 isoform c

TTC36 蛋白结构

TPR_11

TPR_11: TPR repeat (50 - 115)

TPR_2

TPR_2: Tetratricopeptide repeat (128 - 152)

  • 0
  • 100
  • 189 a.a.
蛋白主名 其他名称

tetratricopeptide repeat protein 36

HSP70 binding protein 21

关联疾病

疾病名称 别名
Tyrosinemia, Type Iii

Tyrosinemia Type Iii

4-Hydroxyphenylpyruvate Dioxygenase Deficiency

TYRSN3

4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

Tyrosinemia Type 3

4-Alpha Hydroxyphenylpyruvate Dioxygenase Deficiency

4-Alpha Hydroxyphenylpyruvic Acid Oxidase Deficiency

Tyrosinemia Due To 4-Hydroxyphenylpyruvate Dioxygenase Deficiency

Tyrosinemia Due To 4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

Tyrosinemia Due To Hpd Deficiency

Tyrosinemia 3
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15211 TTC36 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TTC36 VGNC VGNC:47954
Mus musculus TTC36 MGD MGI:2384760
Bos taurus TTC36 VGNC VGNC:36472
Macaca mulatta TTC36 VGNC VGNC:107660
Rattus norvegicus TTC36 RGD RGD:1359544
Felis catus TTC36 VGNC VGNC:81098
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