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  2. GPR27 - G protein-coupled receptor 27 Gene

GPR27 - G protein-coupled receptor 27 Gene

中文名称:G 蛋白偶联受体 27

种属: Homo sapiens

同用名: SREB1

基因 ID: 2850 | 基因类型: protein coding

关于 GPR27

Cytogenetic location: 3p13 Genomic coordinates (GRCh38): 3:71,753,855-71,756,496 (from NCBI)

This gene has 1 transcript (splice variant), 156 orthologues and 2 paralogues.

功能概要

GPR27 是 G 蛋白偶联受体 (GPCR) 的成员,GPCR 是一大类受体,具有以 7 个跨膜结构域为特征的相似结构。细胞外刺激物 (如神经递质、激素或光) 激活 GPCR 会诱导由异三聚体 GTP 结合蛋白或 G 蛋白介导的细胞内信号级联反应。[OMIM 提供,2010 年 5 月]

GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, Hormones, or LIGHT induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010]

GPR27 基因产物(1)

mRNA Protein Name
NM_018971.3 NP_061844.1 probable G-protein coupled receptor 27

GPR27 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (35 - 337)

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  • 375 a.a.
蛋白主名 其他名称

probable G-protein coupled receptor 27

super conserved receptor expressed in brain 1

关联疾病

疾病名称 别名
Eyelid Disease

Eyelid Diseases

Eyelid Disorders

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus GPR27 MGD MGI:1202299
Rattus norvegicus GPR27 RGD RGD:71067
Felis catus GPR27 VGNC VGNC:102594
Macaca mulatta GPR27 VGNC VGNC:84175
Bos taurus GPR27 VGNC VGNC:106758