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  2. ALKAL1 - ALK and LTK ligand 1 Gene

ALKAL1 - ALK and LTK ligand 1 Gene

中文名称:ALK 和 LTK 配体 1

种属: Homo sapiens

同用名: AUGA; AUGB; FAM150A; UNQ9433

基因 ID: 389658 | 基因类型: protein coding

关于 ALKAL1

Cytogenetic location: 8q11.23 Genomic coordinates (GRCh38): 8:52,534,037-52,565,430 (from NCBI)

This gene has 2 transcripts (splice variants) and 161 orthologues. Biased expression in gall bladder (RPKM 1.3), thyroid (RPKM 1.1) and 7 other tissues.

功能概要

启用受体信号蛋白酪氨酸激酶激活剂活性和受体酪氨酸激酶结合活性。参与 ERK1ERK2 级联的正向调控; ERK5 级联的正调控;和神经元投射发育的正调节。预测位于细胞外区域。 [由基因组资源联盟提供,2022 年 4 月]

Enables receptor signaling protein tyrosine kinase activator activity and receptor tyrosine kinase binding activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of ERK5 cascade; and positive regulation of neuron projection development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ALKAL1 基因产物(1)

mRNA Protein Name
NM_207413.4 NP_997296.1 ALK and LTK ligand 1 precursor

ALKAL1 蛋白结构

FAM150

FAM150: FAM150 family (56 - 128)

  • 0
  • 100
  • 129 a.a.
蛋白主名 其他名称

ALK and LTK ligand 1

AUG-beta

重组 ALKAL1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71584 ALKAL1 Protein, Human (His, B2M) Q6UXT8 (R28-T129) ≥95%

关联疾病

疾病名称 别名
Inflammatory Myofibroblastic Tumor

Inflammatory Fibrosarcoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ALKAL1 VGNC VGNC:83979
Mus musculus ALKAL1 MGD MGI:3645495
Canis familiaris ALKAL1 VGNC VGNC:49887
Felis catus ALKAL1 VGNC VGNC:105869
Rattus norvegicus ALKAL1 RGD RGD:1583530
Others ALKAL1 NCBI