1. Gene
  2. C1RL - complement C1r subcomponent like Gene

C1RL - complement C1r subcomponent like Gene

中文名称:补充 C1r 子组件样

种属: Homo sapiens

同用名: C1RL1; C1RLP; CLSPa; C1r-LP

基因 ID: 51279 | 基因类型: protein coding

关于 C1RL

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,094,554-7,109,214 (from NCBI)

This gene has 12 transcripts (splice variants), 1 gene allele, 199 orthologues and 16 paralogues. Ubiquitous expression in liver (RPKM 37.4), adrenal (RPKM 16.4) and 22 other tissues.

功能概要

预测启用丝氨酸型内肽酶活性。预计参与酶原激活。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

C1RL 基因产物(4)

mRNA Protein Name
NM_001297640.2 NP_001284569.1 complement C1r subcomponent-like protein isoform 2 precursor
NM_001297642.2 NP_001284571.1 complement C1r subcomponent-like protein isoform 3 precursor
NM_001297643.2 NP_001284572.1 complement C1r subcomponent-like protein isoform 4 precursor
NM_016546.4 NP_057630.2 complement C1r subcomponent-like protein isoform 1 precursor

C1RL 蛋白结构

CUB

CUB: CUB domain (47 - 148)

Trypsin

Trypsin: Trypsin (247 - 479)

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  • 487 a.a.
蛋白主名 其他名称

complement C1r subcomponent-like protein

C1r-like protein

关联疾病

疾病名称 别名
Ovary Adenocarcinoma

Ovarian Adenocarcinoma

Adenocarcinoma Of The Ovary

Ovarian Adenoacanthoma

Adenocarcinoma Of Ovary

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta C1RL VGNC VGNC:108329
Mus musculus C1RL MGD MGI:2660692
Bos taurus C1RL VGNC VGNC:26629
Canis familiaris C1RL VGNC VGNC:38587
Rattus norvegicus C1RL RGD RGD:1302936