1. Gene
  2. RIOK2 - RIO kinase 2 Gene

RIOK2 - RIO kinase 2 Gene

中文名称:RIO 激酶 2

种属: Homo sapiens

同用名: RIO2

基因 ID: 55781 | 基因类型: protein coding

关于 RIOK2

Cytogenetic location: 5q15 Genomic coordinates (GRCh38): 5:97,160,867-97,183,247 (from NCBI)

This gene has 7 transcripts (splice variants), 198 orthologues and 3 paralogues. Ubiquitous expression in thyroid (RPKM 5.0), ovary (RPKM 4.8) and 25 other tissues.

功能概要

预测启用蛋白激酶活性。参与多个过程,包括 rRNA 加工的正调控;核糖体小亚基从细胞核输出的正调控;和有丝分裂中期/后期转变的调节。位于细胞质中。前核糖体的一部分,小亚基前体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein kinase activity. Involved in several processes, including positive regulation of rRNA processing; positive regulation of ribosomal small subunit export from nucleus; and regulation of mitotic metaphase/anaphase transition. Located in cytoplasm. Part of preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Apr 2022]

RIOK2 基因产物(2)

mRNA Protein Name
NM_001159749.2 NP_001153221.1 serine/threonine-protein kinase RIO2 isoform 2
NM_018343.3 NP_060813.2 serine/threonine-protein kinase RIO2 isoform 1

RIOK2 蛋白结构

Rio2_N

Rio2_N: Rio2, N-terminal (9 - 91)

RIO1

RIO1: RIO1 family (108 - 279)

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  • 552 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase RIO2

关联疾病

疾病名称 别名
Cecum Carcinoma

Cecum Cancer

Caecum Carcinoma

Carcinoma Of Cecum

Cecal Cancer

Malignant Neoplasm Of Caecum

Malignant Tumor Of The Cecum

Cecum Adenocarcinoma

Cecal Adenocarcinoma

Adenocarcinoma Of Cecum

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta RIOK2 VGNC VGNC:76774
Bos taurus RIOK2 VGNC VGNC:50056
Felis catus RIOK2 VGNC VGNC:97605
Mus musculus RIOK2 MGD MGI:1914295
Rattus norvegicus RIOK2 RGD RGD:1311588
Canis familiaris RIOK2 VGNC VGNC:53201
Others RIOK2 NCBI