2. Gene
  3. PTGER2 - prostaglandin E receptor 2 Gene

PTGER2 - prostaglandin E receptor 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：前列腺素 E 受体 2

种属: Homo sapiens

同用名: EP2

基因 ID: 5732 | 基因类型: protein coding

关于 PTGER2

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:52,314,312-52,328,598 (from NCBI)

This gene has 2 transcripts (splice variants), 245 orthologues, 7 paralogues and is associated with 1 phenotype. Broad expression in bone marrow (RPKM 14.8), stomach (RPKM 7.9) and 19 other tissues.

功能概要

该基因编码前列腺素 E2 的受体，前列腺素 E2 是花生四烯酸的一种代谢物，在多种组织中具有不同的生物活性。该基因的突变与阿司匹林引起的哮喘易感性有关。[RefSeq 提供，2009 年 10 月]

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]

PTGER2 基因产物(1)

mRNA Protein Name
NM_000956.4 NP_000947.2 prostaglandin E2 receptor EP2 subtype

PTGER2 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (62 - 314)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
蛋白主名 其他名称

prostaglandin E2 receptor EP2 subtype

PGE receptor EP2 subtype

关联疾病

疾病名称 别名
Asthma, Nasal Polyps, And Aspirin Intolerance

Asthma And Nasal Polyps

Asa Triad

Asthma, Aspirin-Induced, Susceptibility To

Asthma, Aspirin-Induced

Asthma, With Nasal Polyps And Aspirin Intolerance

ANPAI

Aia

Aspirin-Intolerant Asthma

Asthma Aspirin-Induced

Nasal Polyps Asthma And Aspirin Sensitivity

Samter Triad

Asthma With Aspirin Triad Including Nonsteroidal Anti-Inflammatory Activity And Nasal Polyps
Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus
Ocular Hypotension

Hypotony Of Eye
Iritis
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108560 (+)-Fluprostenol Activator 97.00% 否
HY-RS11376 PTGER2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-108560A 15(S)-Fluprostenol Activator / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PTGER2 VGNC VGNC:33502
Macaca mulatta PTGER2 VGNC VGNC:76468
Mus musculus PTGER2 MGD MGI:97794
Rattus norvegicus PTGER2 RGD RGD:620020
Canis familiaris PTGER2 VGNC VGNC:45143
Others PTGER2 NCBI
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