1. Gene
  2. TP53AIP1 - tumor protein p53 regulated apoptosis inducing protein 1 Gene

TP53AIP1 - tumor protein p53 regulated apoptosis inducing protein 1 Gene

中文名称:肿瘤蛋白 p53 调节凋亡诱导蛋白 1

种属: Homo sapiens

同用名: P53AIP1

基因 ID: 63970 | 基因类型: protein coding

关于 TP53AIP1

Cytogenetic location: 11q24.3 Genomic coordinates (GRCh38): 11:128,934,731-128,942,871 (from NCBI)

This gene has 6 transcripts (splice variants) and 14 orthologues. Biased expression in skin (RPKM 6.8) and esophagus (RPKM 1.6).

功能概要

该基因在胸腺中特异性表达,并编码定位于线粒体的蛋白质。该基因的表达可由 p53 诱导,并且被认为在介导 p53 依赖性细胞凋亡中发挥重要作用。已经针对该基因描述了编码不同亚型的选择性剪接转录物变体。[RefSeq 提供,2011 年 10 月]

This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent Apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

TP53AIP1 基因产物(4)

mRNA Protein Name
NM_001195194.1 NP_001182123.1 p53-regulated apoptosis-inducing protein 1 isoform c
NM_001195195.2 NP_001182124.1 p53-regulated apoptosis-inducing protein 1 isoform b
NM_001251964.2 NP_001238893.1 p53-regulated apoptosis-inducing protein 1 isoform d
NM_022112.3 NP_071395.2 p53-regulated apoptosis-inducing protein 1 isoform a

TP53AIP1 蛋白结构

TPIP1

TPIP1: p53-regulated apoptosis-inducing protein 1 (1 - 124)

  • 0
  • 100
  • 124 a.a.
蛋白主名 其他名称

p53-regulated apoptosis-inducing protein 1

关联疾病

疾病名称 别名
Bartter Syndrome, Type 2, Antenatal

Bartter Disease Type 2

BARTS2

Hyperprostaglandin E Syndrome 2

Bartter Syndrome, Type 2

Bartter Syndrome Type 2

Hypokalemic Alkalosis With Hypercalciuria Antenatal 2

Hypokalemic Alkalosis With Hypercalciuria 2, Antenatal

Bartter Syndrome Type 2 Antenatal

Hypokalemic Alkalosis With Hypercalciuria 2 Antenatal

Bartter Syndrome Antenatal Type 2

Bartter Syndrome Type Ii

Bartter Syndrome 2, Antenatal

Abs2

Antenatal Bartter Syndrome 2

Bartter Syndrome 2

Bs2

Hyperprostanglandin E Syndrome 2

Bartter Syndrome, Antenatal , Type 2

Antley-Bixler Syndrome, Autosomal Dominant

Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma